目的 了解依托芬那酯凝胶对有疼痛症状的轻中度拇外翻畸形的治疗效果。 方法 对2010年3月－2011年7月门诊收治的轻中度拇外翻患者共65足，随机分成两组，治疗组采取托芬那酯凝胶局部应用和佩戴夜间支具，对照组佩戴夜间支具，局部应用安慰剂，治疗周期1个月。记录症状明显缓解时间，治疗前后对患者进行视觉模拟疼痛评分和美国骨科足踝分会跖趾及趾间关节评分，并测量拇外翻角和第一跖骨间角改变。 结果 全部患者完成治疗，疼痛缓解时间治疗组为（3.28 ± 1.04）d，对照组（7.03 ± 2.15）d，差异有统计学意义（P＜0.05）,佩戴足矫形器治疗1个月，拇外翻角和第一跖骨间角改变无统计学差异（P＞0.05）。 结论 局部应用依托芬那酯凝胶结合足矫形器治疗轻中度拇外翻能快速缓解疼痛症状，改善活动能力，延缓畸形加重，依托芬那酯凝胶局部给药患者能良好耐受，可避免口服非甾体抗炎药（NSAIDs）带来的副作用。
Plantar pressure distribution can reflect the force of several key points on foot while standing and walking. A comprehensive understanding of the plantar pressure distribution makes great sense in the following aspects:the understanding of the normal foot biomechanics and function, clinical diagnosis, measurement of disease extent, postoperative efficacy evaluation, and rehabilitation research. A simple plantar pressure measurement device was designed in this study. This paper uses FlexiForce flexible sensor to pickup plantar pressure signal and USB A/D board to do data acquisition. The data are transferred into a laptop and processed by a VB-based software which can display, remember and replay the data. We chose patients with hallux valgus and normal people to measure the pressure distribution and make contrast analysis of plantar pressure with this device. It can be concluded that people with hallux valgus have higher pressure on the second metatarsophalangeal joint and the distribution move outward. The plantar pressure of patients postoperative could be greatly improved compared to the preoperative. The function of this device has been confirmed.