【摘要】 目的 探讨介入治疗股骨头无菌性坏死（ANFH）的疗效。 方法 纳入1996-2009年间确诊的ANFH患者15例，采用经外周动脉穿刺插管的方法，经血管造影明确供血血管的位置，经导管向其内灌注扩张血管药、舒筋活血中药和溶栓药物，以改善股骨头供血状况；并追踪随访1~3年，根据杨白明评定标准从疼痛、功能、X线片3个方面进行判定，观察其临床症状的改善。 结果 Ⅰ~Ⅲ期ANFH患者的临床症状减轻，甚至消失；痊愈50%，显效25%，有效15%。 结论 介入治疗Ⅰ~Ⅲ期ANFH的疗效显著。【Abstract】 Objective To investigate the curative effects of interventional therapy in aseptic necrosis of the femoral head (ANFH). Methods Fifteen patients with ANFH diagnosed from 1996 to 2009 were respectively analyzed. With peripheral arterial puncture methods from peripheral artery, the feeding artery was clarified by using angiography and infused the angiectasia agent, traditional Chinese medicine which could distend blood vessel and thrombolysin to improve blood supply of femoral head. All patients were followed up for one to three years to observe improvement of clinical symptoms. Results Clinical symptom of ANFH in stage Ⅰ-Ⅲ were alleviated or even disappeared, among whom 50% were removed, 25% were markedly effective, and 15% were effective. Conclusion Interventional therapy has significant curative effect in treating ANFH, especially for stage Ⅰ-Ⅲ.