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find Author "曹子昂" 10 results
  • 后纵隔巨大畸胎瘤一例

    Release date:2016-08-30 05:48 Export PDF Favorites Scan
  • 32例食管穿孔的分级与治疗

    Release date:2016-08-30 06:02 Export PDF Favorites Scan
  • The Surgical Treatment of Lung Cancer with Cerebral Metastasis

    Objective To investigate the feasibility and clinical value of combined treatment for lung cancer with cerebral metastasis. Methods From May 1999 to May 2005, twentyone patients diagnosed lung cancer with cerebral metastasis received treatment in our hospital. The management consists of cerebral lesion resection, chemotherapy, lung cancer resection and chemotherapy or radiotherapy. Then evaluate the short-term and long-term outcome. Results No severe complications occurred in hospital. The 1-, 2-, and 3-year survival rates were 75.0%(12/16), 37.5%(6/16), and 12.5%(2/16) respectively. Life quality was promoted significantly. Conclusion Although lung cancer with cerebral metastasis is classified as stage Ⅳ,the effect of combined treatment is favorable because of the special metastatic position. But the choice of the patient is important.

    Release date:2016-08-30 06:15 Export PDF Favorites Scan
  • 原发性纵隔肿瘤的外科治疗

    目的总结原发性纵隔肿瘤的外科治疗经验。方法回顾性分析我院1986年6月~2004年12月122例原发性纵隔肿瘤患者的临床资料,肿瘤全部切除107例,肿瘤大部分切除6例,单纯探查活检9例,手术切除率为92.6%(113/122)。结果手术死亡2例,术后94例患者获得随访,随访3个月~18年。除1例良性胸腺瘤切除术后7个月肿瘤复发外,其余良性纵隔肿瘤患者术后均预后良好。2例年轻的胸腺癌患者分别在术后3个月和5个月死于癌肿复发及其引起的各种并发症。结论原发性纵隔肿瘤不论良性还是恶性,只要无明确的远处转移和呼吸循环系统功能不全,允许胸部探查者均应及早手术,争取摘除肿瘤。

    Release date:2016-08-30 06:18 Export PDF Favorites Scan
  • 胸腺瘤合并重症肌无力及单纯红细胞再生障碍性贫血二例

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • 再次心瓣膜置换术203例

    目的 总结再次心脏瓣膜手术患者的外科治疗经验。 方法  2 0 3例患者中首次术式行二尖瓣闭式扩张术 117例 ,二尖瓣直视分离术 13例 ,二尖瓣生物瓣置换术 6 9例 ,生物瓣主动脉瓣置换术 4例 ;再次手术方式为二尖瓣置换术 185例 ,双瓣膜置换术 14例 ,主动脉瓣置换术 4例 ,同时行三尖瓣成形术 5 2例 ,左心房血栓清除术 2 1例。结果  2 0 3例中 ,术中死亡 6例 ,死亡率 2 .96 % ;术后 30天内死亡 19例 ,死亡率 9.6 4 % ,术后死亡原因主要为低心排血量。总死亡率为 12 .32 % ,其中 1981~ 1988年围术期死亡率为 35 .2 9% (12 /34) ,1989~ 1994年为 10 % (9/90 ) ,1994年以后为 5 .0 6 % (4 /79)。术后发生较严重的并发症 5 2例 ,占总病例数的 2 5 .6 2 %。 结论 再次瓣膜病变患者需尽早行手术治疗 ,积极改善术前心肺功能 ,术中加强心肌保护及缩短体外循环时间 ,术后积极防治并发症是保证治疗成功的关键

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • 贲门癌术后吻合口复发癌的再手术治疗

    目的 探讨贲门癌术后吻合口复发癌再手术的可能性和适应证. 方法 再次手术采用胸腹联合切口和左胸切口,手术切除9例,术中姑息性置管2例,探查3例. 结果 术后发生严重并发症2例,无手术及院内死亡.手术切除者中2年和3年生存率分别为44.4%(4/9)和22.2%(2/9),5例分别在7个月~2年内死亡,2例失访.置管及探查者均在2~7个月内死亡. 结论 贲门癌术后吻合口复发癌再手术要求较高,须严格掌握手术适应证.如患者一般情况较好,病灶较小,无远处转移,仍可再次积极手术,尤其是首次经腹手术者为佳.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • Correlation between Expression of Thyroid Transcription Factor 1 and Gene Mutation of Epidermal Growth Factor Receptor in Patients with Resectable Lung Adenocarcinoma

    ObjectiveTo explore the correlation between expression of thyroid transcription factor-1 (TTF-1) and gene mutation of epidermal growth factor receptor (EGFR) in patients with resectable lung adenocarcinoma (LAC). Method Sixty-seven LAC patients who underwent surgical resection in the Department of Cardiothoracic Surgery of Shanghai No.6 Hospital and Department of Thoracic Surgery, Renji Hospital, School of Medicine of Shanghai Jiaotong University from June 2009 to December 2012 were enrolled in this study. There were 40 male and 27 female patients with their age of 37-79 (56.7±1.8) years. TTF-1 expression was detected by immunohistochemistry. EGFR gene mutation was examined with mutant-enriched polymerase chain reaction. The correlation between TTF-1 expression and EGFR gene mutation was analyzed with corrected chi-square test. ResultsAmong the 67 LAC samples, 57 samples were TTF-1 positive and 10 samples were TTF-1 negative. There was EGFR gene mutation in 44 samples. EGFR gene mutation rate was 73.7% (42/57) in TTF-1 positive patients and 20.0% (2/10) in TTF-1 negative patients. The sensitivity of TTF-1 expression to predict EGFR mutation was 95.5%, and the specificity was 34.8%. ConclusionEGFR gene mutation rate is higher in LAC patients with positive TTF-1 expression. Positive TTF-1 expression can be used to predict EGFR gene mutation in LAC patients.

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  • Preoperative NRS2002 Assessment of Nutritional Risk of Patients with Esophagus Cancer and Postoperative Results

    ObjectiveTo evaluate nutritional risk of patients with esophagus cancer before operation using nutritional risk screening 2002 (NRS2002), and explore the relationship between nutritional risk score and postoperative results. MethodsWe prospectively evaluated the nutritional risk of 225 patients with esophagus carcinoma patients who were admitted in Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine between March 2012 and March 2013 using NRS2002, in accordance with disease severity score, nutritional status score and age score(age≥70 years old score was 1 point, < 70 years old for 0 point). There were 136 males and 89 females with age of 64.0±8.2 years (ranged from 41 to 85 years). Postoperative results include postoperative complications, mortality, and length of hospital stay. ResultsThe number of patients with preoperative score≥3 points was 75 (33.3%), < 3 points was 150 (66.7%). The incidence rate of postoperative complications was 26.7% in the patients with NRS2002 score≥3 points, and was 12.0% in those with NRS2002 score < 3 points(P < 0.05). And the total hospital stay time was longer in the patients with NRS2002 score≥3 points than that with NRS2002 score < 3 points(29.80±7.94 d vs. 15.30±2.05 d, P < 0.05). Logistic regression analysis showed that the preoperative NRS2002, the underlying diseases, and surgical method were risk factors for postoperative complications. ConclusionsPreoperative NRS2002 score≥3 points can predict more postoperative complications and longer hospital stay time in patients with esophagus carcinoma. It indicates that scientific nutrition support is necessary for esophagus carcinoma patients with NRS2002 score≥3 points. NRS2002 can be used as a predictive index of nutritional risk after operation of esophagus carcinoma.

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  • Accurate Drainage for Intrathoracic Anastomotic Leakage after Esophagectomy

    Objective To explore an effective and minimal invasive drainage procedure for intrathoracic anastomotic leakage after esophagectomy. Method A total of 14 patients (10 males and 4 females, aged 48 to 70 years) with encapsulated effusion due to thoracic anastomotic leakage after esophagectomy were performed accurate thoracic drainage which was guided by ultrasonography in Renji Hospital from January 2012 through December 2014. The J shape flexible catheter was placed into the effusion cavity near the leakage. Gasric drainage and enteral nutrition support were conducted as well. Result All the patients with leakage healed smoothly. The hospital stay was 27 to 94 days. Time of drainage was 17 to 89 days. The drainage volume was 5-260 ml per day. No complication related to drainage occurred. Conclusion Placing the J shape flexible catheter for plural drainage guided by ultrasonography or chest CT scan is a desirable and less injured therapy for intrathoracic leakage after esophagectomy.

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