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find Author "朱小凤" 4 results
  • 外周T细胞淋巴瘤的治疗进展

    T细胞淋巴瘤(TCL)是来源于T淋巴细胞的一类恶性淋巴肿瘤,目前尚无统一的最佳治疗方法。虽近年有新的治疗药物,但都只基于少量的病例或小规模的Ⅱ期临床试验。美国国立卫生研究院对于非皮肤型外周TCL的原则为一线治疗方案首选临床试验。且一线巩固方案除低危患者外,应考虑行大剂量化学治疗(化疗)联合造血干细胞移植。另外由于间变性淋巴瘤激酶基因阳性的间变大细胞淋巴瘤预后较好,对处于完全缓解期者无需行干细胞移植。二线治疗方案中,对于耐受大剂量化疗的患者首选临床试验。对于不能耐受大剂量化疗的患者首先考虑参加临床试验,其次使用新药(如阿仑单抗、硼替佐米、地尼白介索、吉西他滨等)及放射治疗,或根据原癌基因或抑癌基因进行治疗。现就其治疗进展作一综述。

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  • Bibliometric analysis of the application of social network analysis methods in the medical and health field

    Objective To understand the research status of social network analysis methods in the medicine and health field, help medical scientific research managers quickly understand the publication situation and research hotspots of the methods, and provide references for them to use social network analysis methods to enter deeper research. Methods PubMed, Web of Science, Springer Link, ScienceDirect, China National Knowledge Infrastructure, Wanfang and VIP databases were searched for related literature on social network analysis methods in the medical and health field from the establishment of databases to April 2022. Bibliometric analysis was used to analyze the included articles. Results A total of 432 articles were included, with 424 in Chinese and 8 in English. The included articles were published between 1993 and 2020, involving 154 journals and 913 key words. The number of documents increased rapidly at first, and then entered a stable stage. The hot research directions were the spread and prevention of diseases and the power of social support networks. Conclusions Although the number of applications of social network analysis methods in the medical and health field has increased year by year and the application flexibility has increased, the application depth is still lacking. Scientific researchers should dig deep into the research direction, combine theory with practice, and focus on innovation.

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  • Mental health status and influencing factors of resident standardized trainees in a first class of the third grade hospital

    Objective To explore the mental health status and the relevant influencing factors of the resident standardized trainees, and to provide reference for the psychological intervention. Methods All the resident standardized trainees in a first class of the third grade hospital in Sichuan from July 2012 to August 2015 were investigated by the questionnaire including symptom checklist 90, demographic characteristics and work condition. Results The detection rate of psychological problem among resident standardized trainees was 24.7% which was higher than the general population. The analysis of logistic regression showed that the training grade, identity, work time and working achievement were the main factors related to psychological problems. Conclusions The psychological problems of resident standardized trainees were prominent because they are in a transformation stage from medical students to clinical doctors. The related department should pay more attention and take measures to improve the resident standardized trainees’ mental health.

    Release date:2017-01-18 08:50 Export PDF Favorites Scan
  • Impact of Community Healthcare Workers’ Knowledge, Attitude and Practice on the Influenza Vaccination among Elderly People

    Objective To explore the impact of community healthcare workers’ (CHWs) knowledge, attitude and practice (KAP) on the influenza vaccination among elderly people. Methods By means of simple random sampling, 1 residential quarter of each communities, 2 communities of each districts, 5 districts of Chengdu city were randomly selected, and the elderly equal to or more than 60-year-old were on-site investigated. Meanwhile, the questionnaire survey was conducted among healthcare workers in the selected communities. Results There were 4 KAP factors played a positive role in influenza vaccination among elderly people: CHWs’ affirmation of the effectiveness of influenza vaccine, explicitly knowing the focus groups for influenza vaccination, recommendation of vaccination in flu season when the elderly visits, and participation in flu-related education activities. When the accuracy rate of each factor got improved by 1%, the influenza vaccination rate would improve by 2.747%, 1.299%, 0.864%, 0.602%, respectively. Conclusion The knowledge, attitude and practice of HCWs have impacts on the influenza vaccination rates of elderly people. They are significant to improve the influenza vaccination rates of the elderly.

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