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find Author "朱德明" 4 results
  • 离心泵在儿童体外循环中的应用

    目的总结离心泵在儿童先天性心脏病体外循环手术中的应用经验。方法40例患者(年龄5.55±4.36岁、体重17.91±11.95kg)中,首次手术29例,二次手术11例。在体外循环中均使用Jostra离心泵,转流过程中随时调整转速,保证在不同阻力下有相对恒定的灌注流量。结果浅低温平行循环2例,深低温停循环(DHCA)4例,深低温低流量(DHLF)3例,DHCA+DHLF 1例,中低温中高流量30例。总转流时间136.48±87.27min(23~478min),主动脉阻断时间71.61±36.15min(13~153min),DHcA时间12~67min,DHLF时间4~52min。结论离心泵操作简便,预充量小,对血液成分的破坏相对较少,在危重患者中值得推广使用,适合作长时间心室辅助循环使用。

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • Clinical Application of High Flow Rate Modified Ultrafiltration

    Objective To compare the clinical effect between high flow rate modified ultrafiltration (HMUF) and conventional modified ultrafiltration(CMUF), and the effect on hemodynamic data and inflammatory mediators. Methods Forty children were divided into two groups with random number table, HMUF group and CMUF group, 20 cases each group. Hematocrit (HCT) and hemodynamic changes were recorded and the concentration of tumor necrosis factor (TNF) and interleukin 6 (IL-6) were measured. Results The operations were done uneventfully with moderate hypothermia cardiopulmonary bypass in 40 patients. Duration of ultrafiltration of HMUF group (7.83±0. 75 min) was less than that of CMUF group (13.86±1.95 min, P〈0.01). The volumes ultrafiltrated of HMUF group (440.00±91.86ml) was more than that of CMUF group (372.22±56.52ml, P〈0.01). There are no significant differences about the hemodynamic data, HCT, TNF and IL-6 between two groups. Conclusion The HMUF is safe and efficient,when it was used after pediatric cardiopulmonary bypass, the duration of ultrafiltration can be shortened significantly.

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • 平衡超滤法与改良超滤法的应用比较

    目的 比较平衡超滤法和改良超滤法在小儿心肺转流术(CPB)中使用的效果. 方法 40例先天性心脏病患者,随机分成两组:平衡超滤组(BUF组)和改良超滤组(MUF组),分别在整个CPB期间和停CPB后进行超滤.结果 BUF组在CPB中滤出液体815.0±300.9ml,MUF组滤出液体394.4±81.4ml;BUF组在CPB过程中炎症因子的浓度无明显变化,而MUF组则有上升趋势,CPB结束时BUF组炎症因子浓度明显低于MUF组(P<0.05);MUF组进行超滤时,红细胞压积明显提高,炎症因子浓度有所上升. 结论 平衡超滤法能在CPB中维持较低的体内炎症介质浓度,改良超滤法可以在术后迅速浓缩血液,但对降低炎症介质的浓度影响较小.

    Release date:2016-08-30 06:31 Export PDF Favorites Scan
  • 心脏手术深低温低流量灌注不同血气管理对婴幼儿脑保护的影响

    摘要 目的 在深低温低流量灌注模式下,观察快速降温期应用不同稳态血气管理对婴幼儿脑功能的影响。方法 将20例法洛四联症患者随机分为pH稳态和alpha稳态两组,并根据不同时间点、低流量和血气管理方案随机平均分层行析因分析。脑功能监测为:生化指标、脑温、脑电图、智商等。结果 应用pH稳态的脑部温差较应用 alpha稳态低;复温末alpha稳态组中低流量25ml/kgmin-1乳酸含量最高;术后24小时alpha稳态组中低流量25ml/kgmin-1神经元特异性烯醇酶含量最高;术后 4天脑电图和术后 2个月智商两种稳态组间差别无显著性意义。结论 深低温低流量灌注快速降温期应用pH稳态进行血气管理可起到更好的脑保护作用。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
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