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免疫缺陷综合征合并霜样树枝状视网膜静脉周围炎一例

伴有眼底改变的Niemen-Pick病二例

The Interpretation of the IDSA/SISA Guideline of Diagnosis and Treatment of Complicated Intra-abdominal Infection

前房硅油存留四年一例

Expressions of MCP-1 in Pancreatic Tissues and Intestinal Mucosa of Severe Acute Pancreatitic Rats

ObjectiveTo observe the effects and mechanism of MCP-1 in ileum and pancreatic tissues in rats with severe acute pancreatitis(SAP). MethodsTwenty-fourth healthy SD rats were randomly divided into two groups:control group(n=12) and SAP model group(n=12). SAP was induced in model group by retrograde injection of 3% sodium taucrocholate into the biliopancreatic duct of rats. The control group underwent laparotomy with the manipulation of the intestinal canal. The rats were killed at 12 h and 24 h respectively after operation, blood and tissue samples were collected to detect the indexes as follows:①Expressions of MCP-1 mRNA of pancreatic and ileum tissues were detected by RT-PCR; ②blood plasma MCP-1 and IL-10 levels were detected by ELISA; ③blood plasma AMY and DAO levels were detected by colorimetry; ④the pathological changes of pancreas and ileum tissues were observed. ResultsCompared with the control group, the levels of MCP-1, IL-10, AMY, and DAO in plasma, pancreas, and ileum tissues were significantly increased in SAP model group(P < 0.01), the expressions of MCP-1 mRNA in pancreas and ileum tissues were up-regulated simultaneously(P < 0.01), and pathological scoring increased obviously(P < 0.01). ConclusionThe levels of MCP-1 in plasma, pancreas and ileum tissues are significantly increased in rats with SAP, MCP-1 aggravate the injury of pancreas and ileum tissues.

A study on the classification of intestinal contents based on miniature reflection ultrasound

The present artificial anal sphincter fails to distinguish the different states of intestinal contents. In this study, we tried to distinguish the intestinal content by using a reflection type ultrasonic system, so as to lay the foundation for the development of artificial anal sphincter with sensing function. We measured the numbers of reflected waves when there were solid, liquid, gaseous or no contents in the recta of 30 Bama Miniature pigs. The results showed significant difference among the numbers of reflected waves of the 4 conditions (F = 1 088, P < 0.05). Our research suggested the reflection-type ultrasonic system could be utilized to distinguish various contents inside the intestinal lumen, thus it might offer a new effective method for the development of artificial anal sphincter with sensing function.

闭角型青光眼急性发作缓解后并发脉络膜脱离

报告急性闭角型青光眼急性发作缓解后并发脉络膜脱离7例（7眼）。表现为视力减退，眼压急剧降低到0.798kPa(1kPa=7.5mmHg)以下，前房较发作时更浅，出现全周或鼻侧、颞侧下方脉络膜半球状隆起。停用匹罗卡品，采用皮质类固醇，甘露醇静脉滴注，乙酰唑胺及双氢克尿噻口服加压包扎等治疗有效。 （中华眼底病杂志，1994，10：241-242）

胰十二指肠切除术后出血的病因及处理(附42例分析)

目的总结胰十二指肠切除术(pancreaticoduodenectomy，PD)后出血的原因和防治措施。 方法回顾性分析2008年1月至2014年1月期间哈尔滨医科大学附属第二医院行PD治疗的423例患者的临床资料。 结果PD术后发生出血42例(9.9%)，其中死亡9例(21.4%)。42例中早期出血23例，死亡2例，死亡率为8.7%；晚期出血19例，死亡7例，死亡率为36.8%；早期出血的死亡率低于晚期出血(P=0.014)。腹腔出血28例，死亡7例，死亡率为25.0%；消化道出血14例，死亡2例，死亡率为14.3%，腹腔出血的死亡率高于消化道出血(P=0.028)。轻度出血15例，死亡2例，死亡率为13.3%；重度出血27例，死亡7例，死亡率为25.9%，轻度出血死亡率低于重度出血病死率(P=0.037)。胰管空肠黏膜对黏膜吻合术后发生出血11例，出血率为10.6%，非黏膜对黏膜吻合术后发生出血31例，出血率为9.7%；2组比较，差异无统计学意义(P＞0.05)。手术治疗24例中死亡3例(12.5%)。 结论轻度腹腔出血和消化道出血经非手术治疗多可治愈；晚期腹腔出血手术难度大，可尝试介入治疗；术中精细操作、选择熟练吻合方式，预防胰瘘、胆瘘及腹腔脓肿可减少术后出血的发生。