目的 探讨胆道镜在探查十二指肠损伤中的临床价值。方法 回顾性分析我院2001年3月至2011年2月期间收治的28例十二指肠损伤患者应用胆道镜探查的临床资料。结果 开腹后直视十二指肠球部损伤7例，胆道镜探查发现其中3例合并水平部损伤，2例合并降部与水平部交界处损伤。直视下未见十二指肠损伤患者中胆道镜探查发现十二指肠损伤21例，其中降部5例，水平部6例，降部与水平部交界处3例，升部2例，十二指肠多处伤5例。按Lucas分级，Ⅰ级4例，Ⅱ级12例，Ⅲ级7例，Ⅳ级5例。Ⅰ级损伤患者中3例在胆道镜下未见血肿继续增大，局部损伤未行处理；1例血肿压迫十二指肠导致肠腔狭窄，在胆道镜引导下避开肠系膜血管，切开肠系膜行血肿清除及止血术。Ⅱ级损伤患者中6例在胆道镜引导下避开肠系膜血管切开肠系膜行全层缝合。其他病例分别采用十二指肠破口空肠Roux-en-Y吻合术（Ⅱ级3例，Ⅲ级1例）、十二指肠空肠端端吻合术（Ⅱ级1例，Ⅲ级3例）、十二指肠空肠Roux-en-Y吻合术（Ⅱ级2例，Ⅲ级2例，Ⅳ级1例）、Graham简化术（Ⅲ级1例，Ⅳ级4例），术后通过空肠切口处放置十二指肠内引流。术后发生并发症12例，其中肠瘘2例，胰瘘2例，肠梗阻3例，腹腔脓肿2例，胰腺脓肿3例。死亡3例，治愈25例。结论 在十二指肠损伤患者中应用胆道镜探查，可以确切诊断十二指肠受损情况，防止漏诊，也可以在胆道镜引导下行相应部位的处理。
ObjectiveTo explore the clinical value of modified Soave procedure with stapler for the treatment of Hirschsprung disease. MethodsThe clinical data of 26 patients with Hirschsprung disease adimitted in No.477 hospital from January 2002 to December 2010 were analyzed retrospectively. All the patients underwent modified Soave operation with rectal mucosa and proximal intestine stapled end-to-end. ResultsAll operations were successful without anastomotic leakage, aponeurosis of investment infection, and colonitis. Increased stool frequency presented in two cases, which were cured with astringents on day 15 and 30 after operation, respectively. Mild fecal contamination was in one case. All cases were followed up between 3 months to 60 months, with an average 32 months, without incontinence and constiptation. ConclusionModified Soave procedure with stapler is safe and effective for the treatment of Hirschsprung disease in elder children and adult.