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find Author "李立钧" 3 results
  • 微创经椎间孔腰椎间融合术治疗下腰椎疾患的初步报告

    探讨微创经椎间孔腰椎间融合术(transforaminal lumbar interbody fusion,TLIF)治疗下腰椎疾病的适应证、方法和早期疗效。 方法 2004 年2 月- 2006 年12 月,于METRX X-Tube 扩张套管下,应用TLIF 治疗下腰椎疾患26 例。男16 例,女10 例;年龄47 ~ 71 岁,平均61 岁。Ⅰ~Ⅱ度退行性或峡部裂型腰椎滑脱症12 例,退行性腰椎管狭窄伴节段性不稳9 例,腰椎间盘突出症4 例,腰椎间盘突出症髓核摘除术后复发1 例。均为单节段融合,其中L3、 4 1 例,L4、5 9 例,L5、S1 16 例。病程10 ~ 34 个月。术前视觉疼痛模拟评分法(visual analogue scale,VAS)评分为(8.1 ± 2.2)分。 结 果 术中失血120 ~ 480 mL,手术时间为100 ~ 280 min。1 例术中硬膜囊撕裂,1 例术后出现口止母 背伸肌力下降,均经对症处理后痊愈。患者均获随访12 ~ 26 个月。术后1 周及3 个月VAS 评分分别为(2.3 ± 0.7)分及(3.1 ± 1.2)分,与术前比较差异有统计学意义(P lt; 0.01)。术后3 个月综合疗效评定:优21 例,良5 例。X 线片示椎间隙骨密度均逐渐增加,Cage 无移位、松动、下沉,椎弓根钉无松动、折断,融合率100%。 结论 微创TLIF 适用于腰椎不稳、局限节段椎间盘病变及Ⅱ度以下腰椎滑脱伴神经根管狭窄的患者,具有手术出血少、损伤小等优点。

    Release date:2016-09-01 09:12 Export PDF Favorites Scan
  • REVIEW ON THE PROGRESS OF PERIPHERAL NERVOUS MICROELECTRODE

    Objective To review the progress and application of peripheral nervous microelectrode. Methods The recent articles on peripheral nervous microelectrode were extensively reviewed. The classification, the progress of the peripheral nervous microelectrode and its utilizable prospect in the control of electronic prosthesis were summarized. Results The microelectrodes had favorable functions of selective stimulation and recording. It provided an information transmitting interface between the electric prosthesis and peripheral nerves. Conclusion Peripheral nervous signal is a feasible signal source to control electronic prosthesis.

    Release date:2016-09-01 09:29 Export PDF Favorites Scan
  • RESEARCH PROGRESS OF microRNA IN INTERVERTEBRAL DISC DEGENERATION

    ObjectiveTo comprehensively analyze the relationship between microRNAs and intervertebral disc degeneration at home and abroad. MethodsThe literature about the relationship between microRNAs and intervertebral disc degeneration was reviewed and analyzed. ResultsMicroRNA can lead to intervertebral disc degeneration by regulating the gene expression, thus influencing the cell's apoptosis and proliferation, increasing of the production of inflammatory mediator and protease, which play important roles in intervertebral disc degeneration. ConclusionMicroRNA is a research focus in the field of intervertebral disc degeneration. Further research of the relationship between microRNAs and intervertebral disc degeneration will help to identify the pathogenesis of intervertebral disc degeneration and furnish the new ideal for the diagnosis and treatment of intervertebral disc degeneration.

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