【摘要】 目的 探索显微眼内窥镜在后段眼内异物取出及玻璃体切除术中的应用。 方法 将2005年7月-2006年3月38例眼内异物患者分为试验组（15例）及对照组（23例）。试验组采用显微眼内窥镜下完成对外伤性视网膜玻璃体病变等的处理及眼内异物的取出；对照组采用显微镜直视下行常规玻璃体切割及眼内异物取出术。 结果 试验组术后角膜透明度及眼压恢复、视力提高及视网膜复位等情况均优于对照组；异物取出情况、手术时间和并发症两组无差异。 结论 在观察困难或异物处于极周边时应用显微眼内窥镜，能够在手术中直接取出眼内各个部位异物，及时发现视网膜裂孔并同时行抗青光眼手术，减少对角膜材料的依赖和对角膜的损伤，为及时、准确和安全地手术提供了条件。【Abstract】 Objective To investigate the application of the intraocular micro-endoscope in extracting intraocular foreign bodies (IOFB) and vitrectomy. Methods A total of 38 patients with IOFB from July 2005 to March 2006 were divided into a trial group (15 patients) and control group (23 patients). The treatment for traumatic retinal vitreous lesions and extraction of IOFB were performed under the intraocular micro-endoscope in the trial group; while the conventional vitrectomy and IOFB extraction were performed under the microscope in the control group. Results The degree of corneal recovery, improvement of intraocular pressure, visual acuity, and retinal reattachment were better in the trial group than that in the control group. There was no difference in removal of IOFB, surgical time and complications between the two groups. Conclusion In patients with intraocular foreign bodies and cloudy cornea or other conditions that made the observation difficult, intraocular micro-endoscope is a useful convenience without relying on donated cornea. The practice made the judge of size, location and the distance more and more accurate through the monitor.