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find Author "杨爱琴" 11 results
  • 盘周及环形脉络膜营养不良一例

    Release date:2016-09-02 05:58 Export PDF Favorites Scan
  • Clinical research of macular branch retinal vein occlusion and surveying of the area of foveal avascular zone

    Objective To observe the clinical characteristics of patients with macular branch retinal vein occlusion (MBRVO) and the changes of the area of foveal avascular zone (FAZ).Methods The data of 69 eyes of 69 patients with MBRVO, who had been diagnosed by ophthalmoscopy, slit-lamp examination and fluoresce in angiography, were retrospectively studied. The relationship of locations between artery and vein on the obstructive site, and the characteristics of fundus pictures, retinal vasculature changes and the complications were analyzed. In 69 patients with MBRVO, 36 had the course of disease for more than 3-6 months, of whom the area of FAZ was compared with that of 30 healthy people.Results In 69 patients, superior MBRVO occurred in 45 eyes (65.22%), and inferior MBRVO occurred in 24 eyes (34.78%). Most of the arteries were anterior to the veins at the obstructive site. Four clinical types of MBRVO were found, and the main complication was macular edema. There was a significant difference in area of FAZ between patients with MBRVO and healthy people (P<0.05). Conclusion There are several clinical characteristics of MBRVO with different manifestations. The area of FAZ of patients with MBRVO is obviously lager than that of the healthy people. (Chin J Ocul Fundus Dis,2003,19:269-332)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • Clinical observation on idiopathic macular holes.

    Purpose To observe the clinical features and visual acuity of the eyes with idiopathic macular holes. Methods We reviewed the clinical materials of 23eyes of 18 patients with idiopathic macular holes and the follow up results from 6 to 120 months. Results In the initial examinations of 22 eyes,the numbers of eyes with stagesⅠ-Ⅳ macular holes were5,4,10,3 eyes respectively,and funds fluorescein angiography showed there were focal transmission of choroidal fluorescein in 17 eyes (stagesⅡ~Ⅳ).Macular hole ocurred in one eyes during follow up.At the final examination of 23 eyes,the numbers of eyes with stages Ⅰ~Ⅳ macular holes were 2,2,9,8 eyes respectively .Full-thickness macular hole of 2 eyes closed naturally after posterior vitreous detachment.The time interval of the subjective visual loss on stage Ⅰ was 5-8 months,stageⅡ8-20 months,stageⅢ12-126 months ,and the average visual acuity on stageⅠwas 0.7,stage 0.55,stageⅢ0.08,and stage Ⅳ0.08 Conclusion Approximately 60% of impending (stage Ⅰ) hole progress to full thickness holes, the full thickness holes were usually enlarged and the visual acuity of affected eyes decreased as the natural course was prolonged . (Chin J Ocul Fundus Dis,1998,14:222-223)

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • 175例儿童眼底病眼底荧光血管造影分析

    Release date:2016-09-02 06:12 Export PDF Favorites Scan
  • 氩激光治疗脉络膜血管瘤

    介绍21例脉络膜血管瘤(孤立型19例,弥漫型2例),其中17例接受了氩激光治疗,治疗后视力不增者5例,12例视力有不同程度提高,随访时间平均14个月. (中华眼底病杂志,1993,9:-)

    Release date:2016-09-02 06:35 Export PDF Favorites Scan
  • 视网膜大动脉瘤15例临床分析

    我们收集了1982~1992年15例视网膜大动脉瘤患者.15例患者均行眼底荧光血管造影.其中对10例患者行激光光凝治疗,并对8例患者进行了随访,其中视力增加者5例,不增者3例.由于本病有自愈可能,是否采用光凝治疗,其治疗时机和方式尚有不同见解,本文对该病的病因及治疗进行了讨论. (中华眼底病杂志,1993,9:234-236)

    Release date:2016-09-02 06:35 Export PDF Favorites Scan
  • 氩激光封闭视网膜裂孔治疗视网膜脱离

    作者1986~1990年应用氩激光封闭视网膜裂孔治疗视网膜脱离50例50眼,44眼获得成功,治愈率达88%;6眼失败。视网膜复位后视力提高者19眼(43.2%),不变者22眼(50%),下降者3眼(6.8%)。未发生明显的并发症。并对氩激光治疗视网膜疾病的优点、封闭视网膜裂孔的适应症和禁忌症,以及治疗中的体会进行了讨论。 (中华眼底病杂志,1992,8:168-170)

    Release date:2016-09-02 06:36 Export PDF Favorites Scan
  • 中心凹图案状色素上皮营养不良

    Release date:2016-09-02 06:01 Export PDF Favorites Scan
  • Inhibition effect of complement factor small interference RNA on the angiogenesis of choroidal neovascularization induced by photocoagulation in rats

    Objective To observe the inhibitory effects of construction of complement factor (CFB)small interference RNA (siRNA) on choroidal neovascularization(CNV)induced by photocoagulation in rats.Methods We constructed an expression vector of CFBsiRNA by cutting CFBsiRNA and plasmid pRNATU61/Neo. Experimental CNV was induced by photocoagulation in 42 Brown Norway rats. After the model was set up, the rats were randomly divided into tail intravenous injection, vitreous injection, subretinal injection, and control group; each group except the control one had a corresponding blank plasmid control group. CFBsiRNA was injected 1, 3, and 5 days respectively after photocoagulation in the injection groups; the dosage was 50, 20, and 10 mu;g in tail intravenous injection, vitreous injection, and subretinal injection group respectively, while no injection was give to the control group after photocoagulation. Before and 14 days after photocoagulation, fundus fluorescein angiograoph (FFA) was performed and CNV development was judged by the leakage; the expression of vascular endothelial growth factor (VEGF) and factor Ⅷ were detected by immunohistochemistry. Results The leakage of fluorescein was obvious lower in tail intravenous injection group than that in the control group (chi;2=15.1620,Plt;0.05). The expression of VEGF and factor VIII in tail intravenous injection group at different time points after photocoagulation didnprime;tdiffer much (F=20.35,18.33; Pgt;0.05); while was apparently lower than that in the other groups at different time points (F=77.96,55.68; Plt;0.05).All of the groups, except tail intravenous injection group, had higher expression of VEGF and factor VIII 14 days after photocoagulation compared with that 7 days after photocoagulation (F=60.89, 61.12; Plt;0.05).Conclusions Constructed CFBsiRNA can inhibite CNV by downregulating the expression of VEGF and factor Ⅷ.

    Release date:2016-09-02 05:40 Export PDF Favorites Scan
  • 前部缺血性视神经病变荧光素眼底血管造影的局限性

    Release date:2016-09-02 06:05 Export PDF Favorites Scan
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