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先天性黄斑缺损的光相干断层扫描检查

Objective To investigate the characteristic of OCT images of congenital macular coloboma and its utility in the diagnosis of the diseases. Methods Seven patients (9 eyes) with congenital macular coloboma who had been examined by visual acuity determination, slit lamp examination, ophthalmoscope and fluorescein angiography received OCT scan and fundus color photography. The results were retrospectively analyzed. Results The manifestation of congenital macular coloboma by OCT was the retinal and choroidal tissues focally pitted outwards along with sclera. The 3 dimensions of pit: horizontal diameter 668 - 4 339mu;m (3 119 in average), vertical length 668 - 4 531 mu;m (2 591 in average), pits depth 230 - 2 146mu;m(1 084 in average).The retinal neurosensory layer became thin and defect. And the retinal neurosensory layer was thinner in the centre than that near the edge. Reflection of retinal pigment epithelium was uneven and discontinued. The dark area of choroid was enlarged. Conclusions It can be clearly shown by OCT that abnormal structure of retina and out layer of choroid in congenital macular coloboma. It is implied that the characteristic of OCT is helpful in the diagnosis of congenital macular coloboma. (Chin J Ocul Fundus Dis, 2005,21:97-99)

半剂量维替泊芬光动力疗法治疗特发性浆液性视网膜色素上皮脱离一例

口服痢特灵致兄妹两人视神经病变

黄斑分支静脉阻塞的诊断和视力预后

报告28例28只眼黄斑分支静脉阻塞，综合性治疗21例，平均随访3.4个月。视力恢复在0.5以上、1.0以下者占33.33%，1.0以上者52.38%，低视力14.29%.视力恢复到正常的时间最短15天，最长20个月，平均4.9个月。观察期间无致盲和黄斑囊样水肿及新生血管等并发症。 （中华眼底病杂志，1996，12：227-228）

三家系Leber病视觉诱发电位的观察

黄斑区脉络膜新生血管患眼光动力疗法治疗前后黄斑结构和功能的光相干断层扫描联合微视野检查

The characteristics of optical coherence tomography angiography on choroidal vessels in eyes of unilateral acute central serous chorioretinopathy

ObjectiveTo observe the changes of macular structure and choroidal capillary blood flow density in patients with acute central serous chorioretinopathy (CSC).MethodsProspective cross-sectional study. A total of 24 eyes of 24 patients with monocular acute CSC (case group) diagnosed by clinical examination from Shanxi Eye Hospital during January and March 2018 were included in the study. The eyes (24 eyes) and contralateral eyes (24 eyes) of the patients in the case group were set to CSC group and contralateral eye group, respectively. Twenty-one eyes of 21 healthy volunteers with age and gender matching were selected as normal control group. The macular structure of the eyes were observed by OCT and OCT angiography (OCTA), and the blood vessel density of choroidal capillary layer in the circular area of the macular area with a radius of 1 mm was measured. The paired t-test was used to compare the differences in blood flow density in the choroidal capillaries between the three groups.ResultsThe results of OCT showed that the serous neuroepithelial detachment in the macular area was observed in all eyes of the CSC group, with or without RPE detachment being 20 or 4 eyes, respectively. Of the 24 eyes in the contralateral eye group, 13 eyes (54.2%) had thick choroidal RPE lesions (PPE). There was no abnormality in the retina and choroidal structure in the macular area of the normal control group. The results of OCTA showed that the blood flow density of choroidal capillaries in the CSC group, the contralateral eye group and the normal control group were 1.759±0.132, 1.924±0.463, and 1.940±0.033, respectively. Compared with the eyes of the contralateral eye group and the normal control group, the blood flow density of choroidal capillaries in the CSC group was significantly lower (t=6.611, 6.474; P=0.000, 0.000). There was no significant difference in the blood flow density of choroidal capillary layer between the contralateral eye group and the normal control group (t=1.328, P＞0.05). In the contralateral eye group, there was no significant difference in the blood flow density of choroidal capillary layer between PPE eyes and no RPE eyes (t=0.806, P＞0.05).ConclusionsThere is 54.2% of the contralateral eyes in the monocular acute CSC patients with PPE. The choroidal capillary layer blood flow density is lower than that of the contralateral and normal eyes.