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find Author "梁皓" 2 results
  • Expression of sperm protein 32/OY-TES-1 in retinoblastoma

      Objective To observe the expression of sperm protein (SP) 32/OY-TES-1 in retinoblastoma (RB).Methods Thirty paraffin specimens of pathologically confirmed RB eyeballs were investigated in this study. The SP32/OY-TES-1 mRNA expression of 15 RB tissues, 12 non-tumor retinal tissues and 22 normal eye tissues were detected by reverse transcription polymerase chain reaction (RT-PCR). The SP32/OY-TES-1 protein expression of 30 RB tissues and 24 normal retinal tissues were examined by immunohistochemistry. The relationship between SP32/OY-TES-1 mRNA, protein expression and age, gender, tumor size, tumor differentiation, clinical stage of RB children were analyzed. Results The expression rate of SP32/OY-TES-1 mRNA in RB tissues, non-tumor retinal tissues and normal eye tissues were 86.7%, 16.7% and 36.4% respectively. Compared the expression rate of SP32/OY-TES-1 mRNA in different gender (chi;2=0.744),age(chi;2=1.178),clinical stage(chi;2=1.188),tumor size (chi;2=0.216),tumor differentiation(chi;2=1.885),the differences were not statistically significant (P>0.05). The expression rate of SP32/OY-TES-1 protein in RB tissues was 73.3% and no expression in normal retinal tissues. Compared the expression rate of SP32/OY-TE-1 protein in different gender (chi;2=1.000),agewith le;two years and >two years(chi;2=0.403),tumor size (chi;2=2.274),tumor differentiation(chi;2=0.138), the differences were not statistically significant (P>0.05); but in clinical stage (chi;2=6.193),with or without optic nerve infiltration (chi;2=4.535), the differences were statistically significant(P<0.05). Conclusions SP32/OY-TES-1 is highly expressed in RB. The expression rate of SP32/OY-TES-1 is related to optic nerve infiltration and clinical stage of RB.

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • 获得性免疫缺陷综合征合并巨细胞病毒性霜样树枝状视网膜血管炎一例

    Release date:2016-10-21 09:40 Export PDF Favorites Scan
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