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频域光相干断层扫描分层分析及其在眼科疾病中的应用

光相干断层扫描（OCT）作为一种快速非侵入性和非接触性的检查技术，能对视网膜的解剖结构进行高分辨率的重建。OCT分层分析是随着高分辨率第四代频域（SD）OCT（SD-OCT）广泛应用衍生出来的研究疾病的新方法，能够确定内界膜到Bruch膜之间不同视网膜结构层面的边界并测量相应层面的视网膜结构厚度或面积。有助于对视网膜病变结构和功能研究深入到更细微层面；对了解相关疾病的发生机制，监测评估及早期诊断将会产生深远的影响。但目前分层分析方法尚不十分成熟，在临床或实验过程中，测量时仍存在一定的误差和局限性。还需要以科学审慎的态度解读SD-OCT分层分析的结果，以便客观正确应用这一技术，推动我们对疾病发生发展过程中不同视网膜层面改变的认识不断深入。

Krypton laser treatment ofneovascularization in retinal vein occlusion

Objective To investigate the method and effect of krypton laser photocoagulation for neovascularization in retinal vein occlusion . Methods Tweenty eight eyes of 27 patients with retinal vein occlusion with neovascularization were photocoagulated by krypton green and red laser.The fundus changes were observed by fundus fluorescein angiography after photocoagulation. Results The neov ascularization disappeared completely in 20 eyes and became smaller in 6 eyes,re mained no change in 2 eyes,and the visual acuity improved in 17 eyes (60.7%) after 6 monthes to 2.5 years of follow-up. Conclusion Krypton laser photocoagulation is obviously effective on regression of n eovascularization and prevenion of vitreous hemorrhage in retinal vein occlusion . (Chin J Ocul Fundus Dis, 2001,17:12-14)

氩激光眼内探头眼外引流视网膜下液的临床观察

多波长氪激光治疗视网膜大动脉瘤的疗效观察

The amount of endothelial progenitor cells at different stages of diabetic retinopathy in patients with type 2 diabetes mellitus

　　Objective　To observe the amount of endothelial progenitor cells (EPCs) at different stages of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM). Methods　Sixty patients with type 2 DM were divided into no DR (NDR) group, non-proliferative DR (NPDR)group and proliferative DR (PDR)group according to the examination of fundus and fundus fluorescein angiography, 20 patients in each group. Twenty healthy people were collected as the control group. 6 ml blood samples were taken from all the subjects, and then the EPCs contents in peripheral blood were detected by flow cytometry. Results 　The EPCs contents in peripheral blood of the control, NDR, NPDR and PDR group were (0.0179plusmn;0.0047)%, (0.0151plusmn;0.0086)%, (0.0123plusmn;0.1137)%, (0.0316plusmn;0.0 294)%. The EPCs contents in peripheral blood of the PDR group was significantly higher than those in others (chi;2=43.780, P＜0.05); the EPCs contents in peripheral blood of the NDR and NPDR group were slightly lower than that in the control group (chi;2=5.244, P=0.73); the EPCs contents in peripheral blood of the NPDR group was lower than that in the NDR group (chi;2=6.016, P=0.12). Conclusion　The EPCs contents in peripheral blood decreases in NDR, NPDR patients, while significantly increases in PDR patients.