OBJECTIVE: To discuss the approaches of tissue engineered blood vessels (TEBV) reconstruction. METHODS: The recent literatures about TEBV were widely reviewed. We summarized various types of biomaterials served as scaffold for TEBV and evaluated the construction model of TEBV. And the biological properties of some TEBV were compared. RESULTS: Although the final model of construction of TEBV was not clear, reports in the last two years had shown several important advances in this exciting field. CONCLUSION: Mimicry of some or all of the properties of three layers of natural healthy blood vessels has been the strategy of all TEBV approaches.
ObjectiveTo conclude the current status and research progress on the pathological mechanism, development and management of pancreatic cancer-associated diseases and provide evidence for intervention of such diseases.MethodThe relevant literatures were reviewed, and the research progress on pancreatic cancer-associated diseases were summarized.ResultsThere are many types of pancreatic cancer-associated diseases, and common diseases included pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, mucinous cystic neoplasm, diabetes, and chronic pancreatitis. Although management and following-up about this kind of diseases remain controversial, the basic consensus has been reached.ConclusionAdequate follow-up is required for patients with pancreatic cancer-associated disease, individualized interventions should be taken if necessary.
Electroencephalography (EEG) signals are strongly correlated with human emotions. The importance of nodes in the emotional brain network provides an effective means to analyze the emotional brain mechanism. In this paper, a new ranking method of node importance, weighted K-order propagation number method, was used to design and implement a classification algorithm for emotional brain networks. Firstly, based on DEAP emotional EEG data, a cross-sample entropy brain network was constructed, and the importance of nodes in positive and negative emotional brain networks was sorted to obtain the feature matrix under multi-threshold scales. Secondly, feature extraction and support vector machine (SVM) were used to classify emotion. The classification accuracy was 83.6%. The results show that it is effective to use the weighted K-order propagation number method to extract the importance characteristics of brain network nodes for emotion classification, which provides a new means for feature extraction and analysis of complex networks.
目的 探讨腹腔镜乙状结肠肿瘤手术经脐取标本并脐再造术的可行性和临床应用前景。方法 回顾性分析 2011年1月至2011年12月期间我院普外科同一治疗小组完成6例腹腔镜乙状结肠肿瘤手术经脐取标本并脐再造术患者的手术时间、出血量、吻合口漏、切口感染及术后恢复情况。结果 6例患者均在腹腔镜下顺利完成手术，手术时间120～160min，平均139min；术中出血量30～60ml，平均40ml；术后未发生吻合口漏、腹腔感染、切口感染等并发症；术后平均7.6d出院。手术切口瘢痕隐蔽不易察觉，新“肚脐”形态良好。结论 腹腔镜乙状结肠肿瘤手术经脐取标本并脐再造术是一创新型手术，创伤小，恢复快，操作简单，安全，腹部美容效果明显。
ObjectiveTo evaluate the clinical value of detecting specific IgG against Toxocara canis in intraocular fluid for the diagnosis of ocular toxocariasis(OT). MethodsFifty patients diagnosed as having OT(OT group), 152 otolaryngology patients (serum control group) and 70 other oculopathy patients (intraocular fluid control group) were enrolled in the study. Intraocular fluids(28 aqueous humor and 22 vitreous humor) and serum samples of OT group were analyzed for specific IgG against Toxocara canis by enzymelinked immunosorbent assay, so were the intraocular fluids(46 aqueous humor and 24 vitreous humor) and 152 serum samples of two control group. Specific IgG level was compared between paired serum and intraocular fluids of OT group. Results68.00% serum samples of OT group were positive for specific IgG against Toxocara canis and the U value was 20.42±17.01. The positive rate was 88.00% and U value 25.72±23.04 in intraocular fluids. In serum control group, it was 2.63% and 2.37±2.71 respectively. The intraocular fluids were negative and U value 0.69±0.34 in intraocular fluid control group. The difference of specific IgG level was proved significant between OT group and control group in both serum and intraocular fluid (Z=8.962, 8.120; P=0.000, 0.000). Twenty-eight patients (56.00%) were positive for specific IgG in both serum and intraocular fluid. Six patients (12.00%) were positive only in serum, and 16 patients (32.00%) only in intraocular fluid. The positive rate was significantly higher in intraocular fluid than in serum (χ2=4.720, P=0.028). Moreover, 64.00% intraocular fluid showed higher specific IgG level than pared serum. ConclusionThe complementary detection of intraocular specific IgG have referential value in diagnosing ocular toxocariasis.