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find Author "王娜娜" 2 results
  • Research progress on animal model of hepatocellular carcinoma

    ObjectiveTo summarize the application research progress of animal models of hepatocellular carcinoma at home and abroad in recent years. MethodThe relevant literature on animal models of hepatocellular carcinoma at home and abroad in recent years was reviewed. ResultsAt present, the common animal models of hepatocellular carcinoma mainly included spontaneous animal model, induced animal model, gene modified animal model, transplanted animal model, and humanized animal model. The etiology, pathogenesis, and pathophysiological changes of various animal models were different. The selection of animal models of hepatocellular carcinoma depended on the type and purpose of research. ConclusionsVarious animal models of hepatocellular carcinoma have their own advantages and disadvantages. Researchers should choose different animal models according to their own research purposes to achieve the expected experimental purposes, so that more valuable research results of animal models of hepatocellular carcinoma can be applied to clinical practice, and finally these research results can be truly applied to diagnosis and treatment of hepatocellular carcinoma.

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  • 婴幼儿法洛四联症根治术62例

    目的 总结婴幼儿法洛四联症(TOF)根治术治疗经验,提高婴幼儿TOF根治术的成功率。 方法 2007年5月至2011年12月盛京医院共施行62例年龄≤3岁婴幼儿TOF根治术,其中男35例,女27例;年龄(16.18±10.45) 月,≤1岁30例。所有患儿术前均常规行心脏超声心动图、心脏大血管CT及三维重建、胸部X线片、心电图等检查明确诊断为TOF,全部在体外循环下进行根治手术。 结果 手术早期死亡率6.4% (4/62),4例均死于并发低心排血量综合征。主动脉阻断时间(68.35±21.43) min,体外循环时间(96.90±30.36) min,术后住院时间(12.00±3.68) d。 结论 低龄低体重的婴幼儿行TOF根治术临床效果良好,手术技巧及矫治畸形的方法是手术成功的关键。良好的体外循环转流及心肌保护,加强术后监护对提高婴幼儿TOF根治术的临床效果有重要意义。

    Release date:2016-08-30 05:46 Export PDF Favorites Scan
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