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find Author "王艺超" 8 results
  • 腹腔镜胰十二指肠切除术治疗十二指肠乳头管状绒毛腺瘤一例

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • Advancement of long non-coding RNA in papillary thyroid carcinoma

    Objective The aim of this study is to review the association between long non-coding RNA (lncRNA) and papillary thyroid carcinoma (PTC). Method The relevant literatures about lncRNA associated with PTC were retrospectively analyzed and summarized. Results The expression levels of noncoding RNA associated with MAP kinase pathway and growth arrest (NAMA), PTC susceptibility candidate 3 (PTCSC3), BRAF activated non-coding RNA (BANCR), maternally expressed gene 3 (MEG3), NONHSAT037832, and GAS8-AS1 in PTC tissues were significantly lower than those in non-thyroid carcinoma tissues. The expression levels of ENST00000537266, ENST00000426615, XLOC051122, XLOC006074, HOX transcript antisense RNA (HOTAIR), antisense noncoding RNA in the INK4 locus (ANRIL), and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in PTC tissues were upregulated in PTC tissues, comparing with the non-thyroid carcinoma tissues. These lncRNAs were possibly involved in cell proliferation, migration, and apoptosis of PTC. Conclusion LncRNAs may provide new insights into the molecular mechanism and gene-targeted therapy of PTC and become new molecular marker for the diagnosis of PTC.

    Release date:2017-08-11 04:10 Export PDF Favorites Scan
  • Advancement of transoral endoscopic thyroidectomy vestibular approach

    ObjectiveTo summarize the advancement of transoral endoscopic thyroidectomy vestibular approach (TOETVA).MethodThe relevant literatures about comparative study btween TEOTVA and other thyroidectomy were retrospectively analyzed and summarized.ResultsCompared with the conventional open thyroidectomy or other endoscopic thyroidectomy, even though TOETVA requires a longer operative time, it provides similar surgical outcomes and no scar on the body.ConclusionTOETVA is a safe and effective procedure with excellent cosmetic results for patients with thyroid disease.

    Release date:2020-02-28 02:21 Export PDF Favorites Scan
  • Intrathecal thoracic carcinoma with lateral cervical lymph node metastasis: a MDT discuss of 2 cases

    ObjectiveTo summarize the experience of diagnosis and treatment of 2 cases of intrathyroid thymic carcinoma(ITTC).MethodThe clinical data of 2 patients with ITTC treated in West China Hospital of Sichuan University since July 2019 were analyzed retrospectively.ResultsAfter the discussion of the multidisciplinary team (MDT), the diagnosis and treatment of 2 cases of ITTC were discussed together, and the prognosis of the patients was actively improved through multidisciplinary cooperation.ConclusionMDT cooperative therapy mode should be adopted in the clinical diagnosis and treatment of patients with ITTC in order to provide a better treatment plan.

    Release date:2021-04-25 05:33 Export PDF Favorites Scan
  • Analysis of prevalence of thyroid cancer in 2022 in China: based on the data of China Cancer Registry Annual Report (2005–2018)

    ObjectiveTo analyze the epidemic trend of thyroid cancer in China from 2005 to 2018, and understand the estimated epidemiological situation of thyroid cancer in China in 2022 based on the thyroid cancer registration data reported by the National Cancer Registration Center and the China Cancer Registration Annual Report. MethodsThe cases of new thyroid cancer and deaths in China were analyzed according to the data of approximately 700 cancer registries in 2018 and the data of 106 cancer registries from 2005 to 2018, then stratified by sex, age, urban and rural areas, and main regions in China. And the estimated incidence and mortality of thyroid cancer in China in 2022 were analyzed based on the population data in 2020. Results① The age standardized incidence rate (ASIR) and age standardized mortality (ASMR) of thyroid cancer in China from 2005 to 2018: in the whole population, the ASIR showed a relatively rapid upward trend and the ASMR showed a relatively slower upward trend; The ASIR and ASMR of men were lower than those of women and the trend of change was also slower than that of women; The ASIR of thyroid cancer in the whole urban population was markedly higher than that in the rural population and the average annual rising rate (AARR) in the urban and rural areas was 6.31% and 0.38% respectively, while the ASMR had no obviously difference between the urban and rural populations (the AARR was 3.23% and 2.33% respectively); The ASIR of thyroid cancer was the highest in the eastern region with a markedly rising, but its ASMR had a relatively lower rising rate, while the ASIR in the western region was relatively lower and the ASMR also showed a downward trend, and the ASMR in the central region had a relatively obvious rising rate. ② The estimated incidence and mortality of thyroid cancer in China in 2022: the estimated ASIR and ASMR of the whole population in 2022 was still rising as compared with in 2018 (ASIR: 24.64 per 100 000 vs. 12.01 per 100 000; ASMR: 0.45 per 100 000 vs. 0.37 per 100 000 ); The estimated ASIR and ASMR in women were still much higher than in men (ASIR: 36.51 per 100 000 vs. 13.25 per 100 000; ASMR: 0.55 per 100 000 vs. 0.35 per 100 000); Among the urban and rural populations, the estimated ASIR in urban was still higher than in rural areas (27.87 per 100 000 vs. 17.66 per 100 000), while the estimated ASMR had no marked difference between them (0.41 per 100 000 vs. 0.52 per 100 000). Compared with 2018, the development trend of the ASIR was still rising (urban: 27.87 per 100 000 vs. 15.58 per 100 000; rural: 17.66 per 100 000 vs. 8.95 per 100 000). The age specific ASIR of thyroid cancer showed a marked sex differences, that is, it began to rise rapidly from the 20–30 years old group, and reached the peak at the 45–50 years old group (the highest ASIR was 97.00 per 100 000) in women; However, which had been in a slower upward trend from the 0 to 20 years old group, while it had been rising rapidly from the 20 to 25 years old group, reaching the peak at the 30–35 years old group (the highest ASIR was 31.60 per 100 000) in men. The overall trend of age specific ASMR for thyroid cancer was similar for both males and females, with a slower increase starting from the 0–35 years old age group and continuous rising till 85 years old and above. ConclusionsThe incidence and mortality of thyroid cancer in China are rising, and the disease burden is still severe and the differences are existed in urban and rural areas, sex, age, and main regions. Overall, the prevention and control situation is complex and severe in China.

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  • 腹腔镜单孔脾切除术1例报道

    Release date:2016-09-08 10:46 Export PDF Favorites Scan
  • The molecular landscape of noninvasive follicular thyroid neoplasm with papillary-like nuclear features

    Objective The aim of this study is to review the molecular landscape of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Method The relevant literatures about molecular profiling of NIFTP were retrospectively analyzed and summarized. Results The most common mutation in NIFTP was rat sarcoma viral oncogene homolog (RAS) mutation. B-type RAF (BRAFK601E) mutation, PPARG fusion, and THADA fusion also could be seen. There was usually no BRAFV600E mutation. miRNAs also were found to be differentially expressed in NIFTP. Conclusion The molecular profiling of NIFTP may become a new molecular marker for the diagnosis of NIFTP.

    Release date:2019-01-16 10:05 Export PDF Favorites Scan
  • 纵隔内异位甲状旁腺功能亢进症的诊治体会:附3例报道

    目的分析纵隔内异位甲状旁腺功能亢进症2次手术的原因及防治策略。方法回顾性收集四川大学华西医院(简称“我院”)甲状腺外科2021年11月至2022年3月期间收治的三发性甲状旁腺功能亢进症患者的临床病理资料。结果共收集到3例患者即病例1~3,其中病例1和病例3为女性,病例2为男性,年龄分别为61、48及57岁。3例患者均因肾功能衰竭行维持性血液透析分别达13、10及9年。病例1和2初次均于外院经第1次行甲状旁腺切除+甲状旁腺自体移植术后甲状旁腺激素(parathyroid hormone,PTH)未持续下降而入我院治疗,发现纵隔内异位甲状旁腺,经评估后行机器人或胸腔镜下甲状旁腺瘤切除术,术后PTH显著下降,骨痛症状显著缓解。病例3初次因骨痛就诊于外院(具体不详)给予口服药物对症治疗后PTH仍持续偏高而入我院治疗,发现颈部及纵隔内异位甲状旁腺,经综合评估后行经颈甲状旁腺切除联合胸腔镜纵隔内甲状旁腺肿物切除,术后PTH下降显著,骨痛症状显著缓解。结论对于纵隔内异位甲状旁腺功能亢进症患者,术前联合多途径检查充分评估,选择合适的手术方式,若条件许可行微创治疗,必要时联合术中PTH检测,以减少再次手术风险。

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