Objective To investigate the clinicopathological characteristics of proximal gastric cancer (PGC). MethodsThe clinical course and pathologic feature of 118 PGC patients were analyzed, and compared with those of 310 distal gastric cancer (DGC) patients. ResultsThe incidence of PGC was lower than DGC, the percentage of Ⅲ,Ⅳ stages and undifferentiated type in the PGC group were significantly higher than in DGC. For the surgical procedure, patients in the PGC had significantly higher percentages of total gastrectomy and other organ resection than in DGC. The percentage of patients with positive margin and lymph node metastasis in PGC was also significantly higher than in DGC. Esophageal invasion and lymph node metastasis were much more in PGC. The 5year survival of patients with PGC was significantly lower than that with DGC. No significant differences were found between the two groups with respect to the mortality rates and complications. Conclusion The relatively poor prognosis associated with PGC is mainly from advanced cases and esophageal invasion. Early detection and treatment is the most important strategy to improve the survival of patients with PGC.
【摘要】 目的 探讨子宫腺肉瘤早期的临床表现、影像学特征、组织病理学以及治疗和预后。 方法 对2006年—2010年病理诊断为子宫腺肉瘤的4例青年女性患者进行回顾性分析。 结果 子宫腺肉瘤占同期子宫肉瘤的6.8％（4/58），患者平均发病年龄为40岁，均未绝经。患者均有阴道不规则流血，B型超声示最大1例肿物直径为11 cm，其余结节直径平均约1.5 cm。1例患者的CA125水平高于正常。术后随访期间所有患者身体状态良好，无复发。 结论 子宫腺肉瘤恶性程度较低，如能及时治疗，预后较好。【Abstract】 Objective To investigate the clinical manifestations, imaging features, histopathology, treatment and prognosis of uterine adenosarcoma. Methods The clinical data of four young female patients with uterine adenosarcoma collected from 2006 to 2010 were analyzed retrospectively. Results Uterine adenosarcoma accounted for 6.8% in uterine sarcoma (4/58). All patients were not menopausal, with the average onset age of 40 years old. Abnormal vaginal bleeding were seen in all patients. The diameter of the largest nodule was 11 cm, and the average of the others was 1.5cm approximately in B-ultrasound image. The value of CA125 increased in one patient. During the follow-up period, all patients survived without tumor recurrence. Conclusion Uterine adenosarcoma is a low-grade malignancy. Timely treating may lead to a good prognosis.