目的 初步探讨容易误诊为乳腺癌的乳腺良性疾病的病理类型和临床特征，提高诊断准确率。方法 回顾性分析了1998年9月至2000年1月收治的50例术前诊断为乳腺癌的乳腺良性疾病。 结果 乳腺炎性疾病、纤维囊性增生或／和积乳囊肿、纤维腺病或／和某些纤维腺瘤均易误诊为乳腺癌；此类乳腺良性疾病扪诊的准确性显著低于乳腺钼靶摄片和彩超检查(P＜0.005)。 结论 乳腺良性疾病临床诊断的准确性有赖于病史、乳腺扪诊及乳腺X线摄片和彩超的综合分析。
ObjectiveTo summarize the clinicopathologic features of hepatic epithelioid hemangioendothelioma (EHE). MethodThe clinical and histopathologic features, and follow-up data of 9 patients with hepatic EHE were analyzed retrospectively. Results①There were 4 males and 5 females in 9 patients with hepatic EHE. The age was from 25 years to 69 years.②Five patients presented with nonspecific symptoms such as right upper quadrant pain, fatigue or weight loss. Four patients were asymptomatic.③Macroscopically, the tumors were usually multiple and ranged in size from 0.5 cm to 9.0 cm.④Histologically, the tumors appeared as cords or solid nets that were characterized by epithelioid, histiocytoid, spindle or signet-ring-like cells. The cells often contained vacuoles representing intracellular lumina, in which red blood cells could be seen. The neoplastic cells invaded the surrounding liver tissue and formed papillary or glomeruloid structure in vessels. The stroma was fibrous with myxohyaline areas.⑤Immunohistochemical stain showed that all the tumors were positive for endothelial markers (factorⅧ-related antigen, CD34, CD31, and so on). ConclusionsEHE of liver is a very rare clinical entity. It might be easily misdiagnosed due to EHE without specific clinical and imaging changes. Its final diagnosis depends on pathological and immunohistochemical findings.