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find Author "白海亚" 3 results
  • Clinical Value of Diagnosis of Non-Bloody Nipple Discharge by Combination of Fiberoptic Ductoscopy and Liquid Based Thin-Layer Cytology

    目的 探讨纤维乳管镜(FDS)联合液基薄层细胞学检查(TCT)在诊断非血性乳头溢液中的临床价值。方法 回顾性分析笔者所在医院2008年7月至2011年7月期间因非血性单侧单孔乳头溢液的176例住院患者的临床资料。所有患者均行FDS检查及冲洗液TCT,且均有明确的病理学诊断结果,比较联合法与单一FDS或TCT检查的诊断准确率。结果 FDS的诊断准确率为80.7%(142/176),TCT为53.4%(94/176),联合法为86.9% (153/176)。结论 FDS联合TCT对非血性乳头溢液的诊断准确率高,可以提高FDS检查阴性的乳腺疾病的检出率。

    Release date:2016-09-08 10:36 Export PDF Favorites Scan
  • 荧光法在乳腺癌前哨淋巴结活检中的应用价值

    目的探讨荧光法在乳腺癌患者前哨淋巴结活检(SLNB)中的应用价值。 方法前瞻性收集2014年5月至2015年2月期间甘肃省妇幼保健院收治的乳腺癌患者36例,通过于乳晕处皮内及皮下组织内注射吲哚菁绿(ICG)荧光示踪剂,动态引导定位寻找前哨淋巴结(SLN),分析ICG的示踪效果和SLNB对腋窝淋巴结转移状态的预测效果。 结果36例患者均成功行SLNB,SLN检出率为100%;共检出SLN 86枚,1~3枚/例,平均2.39枚/例;从皮肤切开至取出SLN的手术时间为3~22 min,平均9 min。术中冰冻病理学检查示16例有SLN癌转移,20例无SLN癌转移;1例术中冰冻病理学检查示无SLN癌转移者,术后石蜡切片病理学检查示有SLN癌转移。ICG示踪下SLNB的灵敏度为94.1%(16/17),假阴性率为5.9%(1/17)。 结论荧光法动态引导定位用于乳腺癌SLNB,具有定位准确、检出率高及创伤小的优势,能较准确地预测乳腺癌患者腋窝淋巴结的状态。

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  • Clinical Application of Indocyanine Green Fluorescence in Sentinel Lymph Nodes Biopsy for Breast Cancer

    ObjectiveTo evaluate clinical value of indocyanine green (ICG) fluorescence in sentinel lymph node (SLN) biopsy (SLNB) for breast cancer. MethodThe SLNBs were performed in 66 patients with breast cancer,who were divided into ICG group (n=34) and methylene blue dye group (n=32) according to the tracing method. ResultsThe SLNs were found in 59 patients,the detection rate was 89.39%(59/66).One hundred and sixty-two SLNs in 59 patients were detected,the average number of detected SLNs was 2.75.The SLNs detection rate was 97.06%(33/34) and 81.25%(26/32) in the ICG group and in the methylene blue dye group,respectively,which in the ICG group was significantly higher than that in the methylene blue dye group (P<0.05).The positive SLNs were found in 32 cases,within which was 20 cases in the ICG group,12 cases in the methylene blue dye group.The axillary lymph node metastases were found in 35 of 66 cases,within which was 21 cases in the ICG group,14 cases in the methylene blue dye group.The sensitivity and false negative rate had no significant differences between the ICG group and the methylene blue dye group (sensitivity:95.2% versus 85.7%,P>0.05;false negative rate:4.8% versus 14.3%,P>0.05). ConclusionThe ICG fluorescence in SLNB for breast cancer has many advantages,including shorter time,simple operation,high sensitivity,and high detection rate as compared with methylene blue dye.

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