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find Keyword "精准医学" 21 results
  • Precision Medical Imaging in Big Data: Radiomics

    Objective To summarize the development of process and clinical practice for radiomics. Methods Relevant literatures about the development of process and clinical practice of radiomics were collected to make a review. Results Radiomics, which resulting from big data, had been used in diagnosis, assessment of prognosis, and predictionof therapy response for neoplasm. Conclusion Radiomics is an important part of precision medical imaging in the eraof big data.

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  • The Relation between Precision Medicine and Evidence-based Medicine and Its Application to Cerebrovascular Disease

    Abstract Precision medicine is an ideal medical paradigm which combines modern scientific methods with traditional medical methods to diagnose, treat and evaluate the physical function and nature of diseases more precisely, and to maximize health benefits and minimize the risk of individuals and society with the most effective, safest, and the most economical medical service. Evidence-based medicine is necessary to verify the precision of diagnosis and treatment. In this review, we clarified the conception of precision medicine and the relation between precision medicine and evidence-based medicine. Moreover, we reviewed the application of precision medicine in the field of cerebrovascular disease. We pointed out that such new technologies as genetics, bioinformatics, molecular imaging and management provided tools to realize the idea of precision medicine, and high-quality evidence-based studies provided a guarantee for the clinical practice of precision medicine. In summary, precision medicine is an individualized medical mode that based on the context of a patient's genetic information, living environment and clinical data, etc. to provide precise treatment strategies for the prevention and treatment of disease, but still the promotion of precision medicine should be based on clinical validation under the guidance of evidence-based medicine. Thus, long-term exploration and unremitting efforts are required to achieve the idea of precision medicine.

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  • 我国精准医学的探讨

    2015年美国总统宣布了基于患者基因或生理来定制治疗方案的精准医学国家计划,而精准医疗的概念至少可追溯到21世纪初。我国早在2002年便出现精准医学研究报道,且近年来加快了精准医学的研究步伐,业已上升为国家医学发展战略。为了促进精准医学的研究,进一步推动我国精准医学事业健康、快速地发展,该文进一步探讨了精准医学的狭义和广义概念、诸多特点、研究路径与方法及精准医学发展的对策与展望。

    Release date:2016-12-27 11:09 Export PDF Favorites Scan
  • Advances in precision medicine in the extent of axillary lymph node surgery of breast cancer: to reduce the postoperative breast cancer-related lymphedema in upper limb

    Breast cancer is one of the most common malignant tumors among women. Typically, the operation of breast cancer should include breast surgery and axillary lymph node surgery since breast cancer first metastasizes to regional axillary lymph nodes. However, postoperative breast cancer-related lymphedema (BCRL) in upper limb is the most common long-term complication. The injury to upper limb lymphatic system contributes to causing the postoperative BCRL. Therefore, precision medicine in the extent of axillary lymph node surgery plays an important role in preventing BCRL which can improve the quality of life in breast cancer patients.

    Release date:2018-04-23 05:00 Export PDF Favorites Scan
  • An introduction of the cohort study on chronic diseases of natural population in the living community of Beijing-Tianjin-Hebei region

    This paper introduces the background and research design (including site of investigation, study population, baseline survey and follow-up monitoring), which belongs to the Precision Medicine Project of the National Key Research and Development Program of China.

    Release date:2018-06-20 02:05 Export PDF Favorites Scan
  • Development from empirical medicine to precision medicine: interpretation of Diagnosis for Pulmonary Tuberculosis (WS 288-2017)

    Basing on development of medical model, new national diagnostic standard is interpreted according to three aspects: classification, diagnostic standard, and diagnostic contents. Tracheobronchial tuberculosis and tuberculous pleurisy are added into the classification. The value of molecular and pathological techniques for diagnosis of the pulmonary tuberculosis is emphasized. The status of drug-resistance is included in the diagnostic content. Two opinions are suggested: some practical methods such as diagnostic chemotherapy are indicated in some grassroots areas, while new molecular techniques for detection of DNA/RNA of mycobacteria and resistant mutation are encouraged in some suitable institutions.

    Release date:2018-08-20 02:24 Export PDF Favorites Scan
  • The application of precision medicine in the diagnosis and treatment of tuberculosis

    Precision medicine is a novel medical modality based on genome sequencing, bioinformatics and big data science. The studies regarding tuberculosis always concentrated on the bacteria and host in the setting of precision medicine. This review mainly introduces the application of precision medicine in the diagnosis and treatment of tuberculosis. The limits of the Chinese studies with respect to precision medicine in tuberculosis are also discussed. Moreover, the article predicates its future development.

    Release date:2018-08-20 02:24 Export PDF Favorites Scan
  • Research progress of radiomics in colorectal cancer

    ObjectiveTo summarize the application of radiomics in colorectal cancer.MethodsRelevant literatures about the therapeutic decision-making, therapeutic, and prognostic evaluation of colorectal cancer using radiomics were collected to make an review.ResultsRadiomics is of great value in preoperative stages, therapeutic, and prognostic evaluation in colorectal cancer.ConclusionRadiomics is an important part of precision medical imaging for colorectal cancer.

    Release date:2019-05-08 05:34 Export PDF Favorites Scan
  • Preliminary construction of value judgment framework of precision medicine technology

    ObjectivesTo initially construct a scientific, reasonable and precision medicine technology value judgment framework suitable for China’s national conditions based on expert consultation method, so as to provide scientific value judgment system support for China's medical insurance decision-making.MethodsThe preliminary evaluation indicator system for precision medicine technology value was established by using literature analysis and expert consultation method, and the direct weighting method was used to determine the indicators weight.ResultsAfter two rounds of expert consultation, an indicator system suitable for the value judgment of precision medicine technology in China was constructed, including 5 primary indicators (health needs, health effects, economics, innovation and suitability) and 14 secondary indicators. Each indicator was weighted according to importance.ConclusionsA set of precision medicine value judgment indicator system suitable for China has been initially established, which lays a certain foundation for further measurement research of the indicator system and provides a scientific basis for medical insurance decision-making.

    Release date:2020-09-21 04:26 Export PDF Favorites Scan
  • Ethical challenges of precision medicine in China

    In order to promote the responsible development of precision medicine in China, the current situation of precision medicine in three major fields (clinical, research and commercial) was briefly introduced, and key ethical issues or disputes in each field (including informed consent, return of incidental findings, and allocation of medical resources in the clinical field; informed consent, return of research results, and data use and sharing in the research field; genetic counseling, clinical utility of genetic testing, and use of data in the field of direct-to-consumer genetic testing) were discussed. It is necessary to actively meet these ethical challenges for the development of precision medicine in China.

    Release date:2021-01-26 04:48 Export PDF Favorites Scan
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