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find Author "耿明飞" 2 results
  • The value of esophageal activity examination under X-ray fluoroscopy and chest CT in assessing the resectability of upper thoracic esophageal cancer

    ObjectiveTo investigate the value of esophageal activity examination under X-ray fluoroscopy and chest CT in evaluating the resectability of upper thoracic esophageal cancer.MethodsA total of 221 upper thoracic esophageal carcinoma patients underwent radical operation between 2009 and 2015 in our hospital were enrolled, including 141 males and 80 females with a median age of 59 (47-79) years. Preoperative routine esophageal activity examination under X-ray fluoroscopy and chest enhanced CT were performed to determine whether the tumor had external invasion. The results of the two methods were compared with that observed during the operation.ResultsThe number of patients with esophageal activity score 1-6 was 70, 85, 32, 29, 2 and 3, respectively. The area under the receiver operating characteristic (ROC) curve (AUC) of esophageal activity examination was 0.897 (95%CI 0.85-0.93, P<0.001), and the cut off value was >3. According to the ROC curve activity score, 4-6 points were considered as invasion, and 1-3 points were non-invasion. The sensitivity, specificity, accuracy and misdiagnosis rate of esophageal activity examination was 75.0%, 89.3%, 88.2%, 10.7%, respectively, and those of CT scan were 75.0%, 66.8%, 67.4%, 33.2%, respectively. Compared with CT scan, the specificity of esophageal activity examination was higher and the misdiagnosis rate was lower. Compared with the detection during the operation, 86.7% of patients with actual invasion of trachea and 85.7% of patients with actual invasion of other parts were in accordance with the esophageal activity examination results.ConclusionEsophageal activity examination under X-ray fluoroscopy can accurately predict the resectability of upper thoracic esophageal cancer, which is a useful supplement to chest CT examination, especially in the aspect of judging the relationship between lesions and the trachea.

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  • 纳米碳混悬液在食管癌根治术中的应用

    目的探讨钠米碳混悬液在食管癌根治术中淋巴示踪的应用效果。 方法2012年7月-2013年5月诊治的80例食管癌患者随机分为纳米碳组和对照组各40例,前者于术中先向癌灶周围注入钠米碳后再行根治术,后者则不应用纳米碳直接行食管癌根治术。记录黑染淋巴结与未黑染淋巴结数量以及淋巴结转移情况。 结果钠米碳组平均每例清除(17.9±5.8)枚淋巴结,淋巴结黑染率为51.7%;对照组平均每例清除(14.1±5.3)枚淋巴结,纳米碳组淋巴结清除数明显高于对照组(t=3.041,P=0.003)。纳米碳组黑染淋巴结转移率13.0%,对照组淋巴结转移率7.3%,纳米碳组黑染淋巴结转移率明显高于对照组(χ2=8.379,P=0.004),同时纳米碳组微小转移淋巴结清除率高于对照组(χ2=4.047,P=0.044)。两组术后并发症发生率差异无统计学意义(P>0.05)。 结论钠米碳混悬液淋巴结示踪效果良好,操作简便,能指导医师制定淋巴结清扫方案,为术后提供更加准确的病理分期。

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