目的探讨残胃癌的临床特点和诊治方法。方法对1989~2003年收治的15例残胃癌病例资料进行回顾性分析,观察不同手术方式对预后的影响。结果B-Ⅱ式手术后残胃癌发病率远高于B-Ⅰ式手术; 根治性手术切除8例,根治性切除率为53.3%(8/15); 根治性手术切除患者2年以上生存率为62.5%(5/8),姑息性手术切除患者术后平均生存时间不足1年。结论早期诊断和根治性切除是残胃癌预后的重要因素。
目的 探讨胃大部切除术后残胃功能性排空障碍(FDGE)的发病机理、诊断及治疗。方法 对1993~1998年我科256例胃大部切除术患者的临床资料进行回顾性分析。结果 本组共发生FDGE 12例,发生率为4.7%(12/256),均发生于术后3~12天。于1周内治愈1例(8.3%),2周内治愈8例(66.7%),3周内治愈11例(91.7%); 所有患者于32天之内经保守治疗治愈出院。结论 术后残胃和远端空肠正常的运动功能破坏是发生FDGE的主要原因; 消化道造影及胃镜检查是诊断本病及与机械性梗阻相鉴别的重要方法; 采取非手术治疗一般可治愈,针对胃排空动力学机理采用促胃肠动力药物能收到较好的疗效。
ObjectiveTo study and analyse the correlation between biologic behavior and clinical factors in gastric cancer.MethodsClinical and pathological study of carcinoma of stomach were retrospectively made in 1034 patients. ResultsIn this series,148 of 1034 patients (14.3%) were early gastric cancer.The frequency of lymph nodes metastasis was higher in proximal gastric cancer than distal (P<0.0001).Similar frequency can also be seen in the tumor of larger diameter (P<0.01),deeper invasion (P<0.0001) and poor differentiation (P=0.004).Some difference in ages and sex of patients may be found on the invasion (P=0.003),differentiation (P<0.0001),site (P<0.001) and frequency of lymph nodes metastasis of the tumor (P=0.01).In multifactorial multivariate linear regression analysis,the site of tumor (P=0.003),diameter of tumor (P<0.0001),depth of tumor infiltration (P<0.0001) and the cell differentiation showed significant association with lymph node metastasis,in which the female patient had more lymph node metastasis than male (P<0.001).Depth of tumor infiltration was the most important factor in lymph node metastasis.Numbers of lymph nodes resected were much more in total and distal gastrectomies than that in proximal gastrectomy (P<0.0001). ConclusionThe results of this study suggest that radical gastrectomy with lymphadenectomy is necessary even in all stages of gastric cancer.
目的 探讨胃大部切除术中应用直线型切割缝合器的临床经验及优点。方法 总结直线型切割缝合器的使用方法,并比较分析传统胃大部切除术和采用直线型切割缝合器行胃大部切除术的手术时间和术后并发症。结果 使用直线型切割缝合器使手术时间缩短60~120 min (P=0.000),术后出血并发症明显减少(P=0.024)。结论 应用直线型切割缝合器行胃大部切除术可以缩短手术时间和减少术后出血的发生。
目的 探讨预防胃大部切除术后碱性返流性胃炎的术式。方法 回顾性分析1998年6月至2008年12月期间我科收治的42例行胃大部切除术患者的临床资料,根据不同术式分为传统Billroth-Ⅱ(简称B-Ⅱ)式组(n=21)和改良B-Ⅱ式组(n=21),对2组患者术后胃肠引流液的量、剑突下持续烧灼痛、胆汁性呕吐、体重减轻以及肠胃液返流情况进行比较。结果 传统B-Ⅱ式组胃肠引流液量平均为(300±50) ml,而改良B-Ⅱ式组胃肠引流液量平均为(100±40) ml,2组间比较差异有统计学意义(P<0.05)。传统B-Ⅱ式组剑突下持续烧灼痛12例,胆汁性呕吐8例,体重减轻1例; 而改良B-Ⅱ式组仅出现1例剑突下持续烧灼痛和1例体重减轻,未见胆汁性呕吐病例,2组间比较差异有统计学意义(P<0.05)。传统B-Ⅱ式组发生轻度返流9例,重度返流12例; 改良B-Ⅱ式组仅2例发生轻度返流,1例重度返流,其余均未见返流,2组间比较差异有统计学意义(P<0.05)。结论 与传统B-Ⅱ式相比,改良B-Ⅱ式的碱性返流性胃炎发生率明显降低,术后效果满意。
ObjectiveTo summarize the procedure of transumbilical single incision laparoscopic surgery (SILS) with conventional laparoscopic instruments for different tumor diameter and different site of gastric stromal tumor. MethodThe clinical data, intraoperative procedure, and postoperative recovery of 34 patients with gastric stromal tumor from December 2009 to February 2014 in this hospital were analyzed retrospectively. ResultsThe transumbilical SILS was performed successfully in all the 34 patients.Among these patients, the wedge resection of stomach was perfor-med in 27 patients, distal subtotal gastrectomy was performed in 6 patients, distal subtotal gastrectomy complicated with multivisceral resection was performed in 1 patient.The pathology confirmed that the diameter of tumors was from 0.6 cm to 10.0 cm (average 3.4 cm).The resection margins were tumor free.The risk assessment showed that tumors with extremely low risk were in 9 cases, low risk were in 17 cases, intermediate risk were in 6 cases, high risk were in 2 cases.During surgery, 9 tumors were located on the fundus of stomach, 6 tumors on the gastric greater curvature, 7 tumors on the gastric lesser curvature, 2 tumors on the anterior and posterior wall of the stomach respectively, 3 tumors on the cardia below, 4 tumors on the gastric antrum, tumor invaded the surrounding organs in 1 case.There was no conversion to open or conventional laparoscopic surgery.no intraoperative or postoperative complications were experi-enced in all the patients except one was postoperative intraperitoneal bleeding and one was incision infection.All the patients were followed for an average of 25 months (range 3-49 months), there was no evident recurrence of disease. ConclusionsThe transumbilical SILS for gastric stromal tumor is a feasible and safe technique when performed by an experienced laparoscopic surgeon.The suitable procedure of SILS should be selected for gastric stromal tumor according their different size and location.