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find Author "胡康" 3 results
  • 乳腺包裹性乳头状癌 3 例报道并文献复习

    目的总结乳腺包裹性乳头状癌(encapsulated papillary carcinoma,EPC)的临床病理学特征、诊断、鉴别诊断以及治疗方法,从而加深对 EPC 疾病的认识以及规范诊治。方法回顾性分析遵义医科大学附属医院 2012 年 1 月至 2018 年 11 月期间收治且经术后石蜡标本病理学检查明确诊断为 EPC 患者的临床资料,并结合相关文献总结其临床病理学特征以及治疗方法。结果共收集到 3 例患者,均为女性,年龄分别为 36 岁、50 岁、70 岁。其中 2 例以“发现乳腺肿块”就诊,肿块均为单发,边界清楚;另 1 例以“乳房胀痛伴乳头溢血溢液 2+ 年”入院。2 例患者的免疫表型为 Luminal 型,1 例免疫表型为三阴性型。 2 例 Luminal 型患者以手术治疗为主,而三阴性型以手术治疗及术后化疗为主。3 例患者目前在随访中、无复发及转移。结论乳腺 EPC 是厚的纤维囊壁包裹且囊壁肌上皮缺乏特殊亚型的浸润性癌,预后较好。其中 Luminal 型 EPC 的治疗原则同导管原位癌(ductal carcinoma in situ,DCIS),而三阴性型 EPC 的治疗参照传统型浸润性乳腺癌。

    Release date:2019-03-18 05:29 Export PDF Favorites Scan
  • Retrospective Review of Bile Duct Stent Insertion with Different Pathway in Treatment of Malignant Biliary Obstruction with 42 Cases

    Objective To discuss the value of biliary stent in treatment of malignant biliary obstruction with different pathways of bile duct stent insertion. Methods Fourty-two cases of malignant biliary obstruction whose biliary stent insertions were through operation (n=18), PTCD (n=17) and ERCP (n=7) respectively were reviewed retrospectively. Results The bile duct stents were successfully inserted in all patients through the malignant obstruction and achieved internal biliary drainage. Compared with the level of the bilirubin before operation, it decreased about 100 μmol/L one week after the stent insertion in all patients. Compared with the levels of glutamic oxalacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and glutamyltranspeptidase before operation, they decreased 1 week after the stent insertion (Plt;0.05). The median survival time was 22 weeks. The average survival time was (32.89±33.87) weeks. Two patients died in hospital after PTCD, and the mortality was 4.76%. Complications included 8 cases of cholangitis, 3 cases of bile duct hemorrhage and 2 cases of hepatic failure. Conclusion The bile duct stent insertions through operation, PTCD and ERCP are all effective in relieving the bile duct construction with malignant biliary obstruction. Each method should be chosed according to the systemic and local condition for every patient so as to improve the safety and efficiency, and to decrease the occurrence of complications.

    Release date:2016-09-08 10:57 Export PDF Favorites Scan
  • Effect of Rectal Stump Lavage Before Anastomosis of Anterior Resection for Rectal Cancer (Report of 56 Cases)

    目的 研究直肠癌切除后肠吻合前进行肠腔灌洗的临床作用。方法 对我院2006年6月至2007年2月期间连续56例行直肠癌低位前切除吻合的病例在切除原发灶、行远端封闭吻合前行生理盐水远端肠腔灌洗,收集灌洗前、后2份标本分别涂片行细胞学检查。结果 灌洗前收集液中观察到肿瘤细胞或核异形细胞者7例,中性粒细胞者24例,上皮细胞者4例; 灌洗后所有患者的收集液中均未观察到肿瘤细胞(P<0.05),19例仍有少许中性粒细胞或上皮细胞。结论 低位直肠癌远端肠腔有可能存在脱落的肿瘤细胞。对直肠癌患者手术切除病灶后吻合前行远端肠腔灌洗的方法简单易行,可以显著减少或清除肠腔内可能残留的肿瘤细胞,从而可避免此类原因所致的局部肿瘤复发,值得提倡。

    Release date:2016-09-08 11:07 Export PDF Favorites Scan
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