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find Keyword "脑肿瘤" 11 results
  • Microsurgical Treatment of Pineal Region Tumors

    目的:研究比较松果体区肿瘤的显微外科手术切除不同手术入路及其优缺点。方法:回顾分析收治的48例松果体区肿瘤患者的手术情况及术后表现,并进行分析。结果:48例患者中,经枕小脑幕切开(Poppen)入路31例,幕下小脑上(Krause)入路8例,经胼胝体-穹窿间入路6例,经胼胝体后部(Dandy)入路2例,颞部侧脑室三角部入路1例。肿瘤全切除40例,次全切除5例,大部分切除3例。8例未全切者及病理证实为恶性的病变术后行放疗和(或)化疗,5例术后并发脑积水行分流术,偏盲1例,死亡2例,随访6个月~6年,KPS大于80分者约43例。结论:松果体区肿瘤的手术治疗效果较好,全切率高、死亡率低,合理的入路及体位,娴熟的显微外科手术技巧是手术成功的关键,Poppen入路和Krause入路是符合微创理念的理想入路。

    Release date:2016-09-08 10:14 Export PDF Favorites Scan
  • 脑转移瘤致双眼视盘水肿一例

    Release date:2016-09-02 05:22 Export PDF Favorites Scan
  • 以眼部病变为首发症状的脑肿瘤二例

    Release date:2016-09-02 06:07 Export PDF Favorites Scan
  • 肺癌脉络膜及皮下多发性转移一例

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  • 神经导航下脑肿瘤切除的围手术期护理

    目的 探讨神经导航下脑肿瘤切除手术治疗的护理要点。 方法 对2012年3月-9月收治的20例神经导航下脑肿瘤切除术患者的临床护理资料进行回顾总结。 结果 20例患者安全度过围手术期,无并发症发生。 结论 根据神经导航手术特点,进行有针对性的观察和护理,可减少并发症,使患者安全渡过围手术期。

    Release date:2016-09-07 02:34 Export PDF Favorites Scan
  • 吲哚胺2,3-双加氧酶与脑肿瘤免疫耐受机制的研究进展

    吲哚胺2,3-双加氧酶(IDO)是一种色氨酸代谢初期的限速酶,研究表明免疫抑制剂IDO的表达可诱导肿瘤的免疫耐受,导致肿瘤无限制生长。通过回顾分析多项有关IDO在人类恶性肿瘤及中枢神经系统(CNS)肿瘤中的相关临床研究资料,研究发现抑制IDO的诱导作用会阻碍肿瘤的生长,阻断IDO经犬尿酸途径诱导的色氨酸耗竭过程会抑制肿瘤细胞增殖,同时提高肿瘤的免疫治疗效果。然而,IDO诱导的色氨酸代谢在CNS肿瘤免疫耐受中的作用机制目前尚不明确。深入研究IDO在CNS肿瘤中的免疫耐受作用机制具有重要意义,因此IDO抑制剂有望成为生物治疗脑肿瘤的重要手段之一。

    Release date:2016-09-07 02:38 Export PDF Favorites Scan
  • MRI Findings in Brain Radiation Necrosis Following Radiotherapy for Brain Neoplasm by γknife

    摘要:目的:探讨伽玛刀治疗颅内肿瘤并发放射性脑损伤的MRI影像表现及其组织病理学基础。方法:回顾性分析8例经手术及病理证实的放射性脑损伤的MRI表现;其中,星形胶质细胞瘤4例,转移性腺癌2例,血管母细胞瘤1例,鼻咽癌1例。结果:病变位于小脑半球、额叶、颞叶及顶叶,8例9个病灶共有2种MRI表现:5例6个病灶平扫T1WI呈低、等信号,T2WI呈稍高、高信号,增强扫描呈“结节状”、“花环状”强化;3个病灶平扫为类圆形,T1WI呈均匀低信号,T2WI呈高信号,边界清楚,增强扫描囊腔无强化,囊壁轻度均匀强化。所有病例均有占位效应。结论:伽玛刀所致放射性脑损伤具有一定的特征性,特别是囊状坏死。

    Release date:2016-09-08 09:56 Export PDF Favorites Scan
  • The benefits and risks of prophylactic use of antiepileptic drug therapy in patients with brain tumor-related epilepsy

    ObjectiveAnalysis prophylactic anti-epileptic drugs (AEDs) therapy in patients with brain tumor-related epilepsy (BTE) to observe whether seizures occurance, frequency will decrease, and the adverse reactions risk assessment of the patient's after using AEDs in 3 months and 12 month. MethodsRetrospective analysis of the cases and follow-up data of patients with the diagnosis of brain tumors in the Second Affiliated Hospital of Chongqing Medical University in June 2011 to February 2015. Through the strict inclusion criteria and exclusion criteria review, the sixty-eight standard patients were divided into two groups:treatment group (44 cases) and control group (24 cases), and compared in the incidence of epilepsy and seizure frequency two groups of patients, and observe the adverse reactions after using AEDs. And analyzed the outcome of patients with brain tumors at 3 months and 2 months. ResultsThrough at least 1 year follow up, compared the data of patients in the two groups with seizure incidence at 3 months and with seizures frequency≥3 times at 12 months, the difference was statistically significant (P < 0.05).In the treatment group, however, 7 patients experienced mild adverse reactions, such as dizziness, fatigue, nausea and vomiting, mild white blood cell reduction, mild liver damage, menstrual cycle changes, mental and behavioral abnormalities, etc.A patient discontinued due to mental disorder, and a patient change AEDs due to menstrual cycle change. All patients had no serious adverse reactions. Conclusions①prophylactic use of AEDs can significantly reduce the incidence of seizures at 3 months; ②Although prophylactic use of AEDs did not reduce the incidence of seizures at 12 months, but can reduce the frequency of seizures; ③The risk of adverse reactions of prophylactic use of AEDs in patients with BTE is relatively low.

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  • 儿童巨大桥小脑肿瘤手术的围手术期护理

    目的总结儿童巨大桥小脑肿瘤手术的护理质量控制,保证术中护理质量。 方法回顾性总结2012年1月-2013年3月18例儿童巨大桥小脑肿瘤手术,了解术前家长担心的问题,术前麻醉、皮肤的准备,术中皮肤护理、体温护理等手术室护理质量管理的相关环节,根据围手术期患儿的应激特点及患儿自身特征,以及手术要求,实施有针对性的术前、术中、术后护理。 结果18例儿童巨大桥小脑肿瘤手术体位安全,暴露充分,术者满意,手术时间8.33~11.66 h,平均10.42 h,出血量100~300 mL,未因手术体位的摆放和护理因素而发生并发症。术后1 d恢复良好,格拉斯哥昏迷评分9~12分。 结论在行儿童巨大桥小脑肿瘤手术时,根据围手术期患儿的应激特点及患儿自身特征,以及手术要求,实施有针对性的术前、术中和术后护理,可使手术野暴露充分,保证术中护理质量,减少手术并发症。

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  • 癫痫相关脑肿瘤的临床研究进展

    原发性脑肿瘤是局灶性癫痫的常见病因,理论上说,所有脑肿瘤(包括原发和继发)都可有癫痫发作。但其中有一部分特殊类型的脑肿瘤,生长缓慢,临床病史较长,以癫痫为主要甚至唯一临床表现,药物大多难以控制,影像学见病灶多位于皮质或者近皮质区,常无明显占位效应,多可伴有囊变及钙化,手术切除后多可治愈,目前称之为癫痫相关脑肿瘤。现就其临床研究进展作一系统综述,旨在提高相关医生的认识和重视,避免误诊或漏诊。

    Release date:2018-01-20 10:51 Export PDF Favorites Scan
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