目的比较腹腔镜阑尾切除术(LA)与开腹阑尾切除术(OA)治疗急性阑尾炎的疗效和手术安全性。方法回顾性分析2010年7~12月期间的50例LA患者的临床资料，与同期55例施行OA的患者进行比较。结果LA组与OA组在手术时间及术中出血量方面差异均无统计学意义(Pgt;0.05); LA组术后肠功能恢复时间、下床活动时间及住院时间均明显短于OA组(Plt;0.05)，LA组镇痛药使用率及术后并发症发生率明显少于OA组(Plt;0.05); 但住院费用LA 组高于OA组(Plt;0.05)。结论LA在治疗阑尾炎方面有明显优势，值得推广。
Objective To evaluate the clinical effectiveness of laparoscopic and open appendectomy. Methods Literatures relating to randomized controlled trials in English and Chinese on the comparison of clinical effectiveness after laparoscopic and open appendectomy in appendicitis from PubMed，Wiley Online Library，Medline，Embase，Cochrane，CNKI，VIP，CBM databases were extracted，and methodological quality was evaluated by two reviewers independently with designed extraction form. The Cochrane Collaboration’s RevMan 4.2.2 software was used for data analysis. The wound infection，hospitalization time，operation time，hospitalization expenses，and peritoneal abscess were compared between laparoscopic and open appendectomy. Results Eight published reports of eligible studies were extracted. Compared with the open appendectomy， laparoscopic appendectomy had significant differences in lower wound infection rate 〔OR=0.19，95%CI （0.09，0.38），P＜0.000 01〕， longer operation time 〔WMD=3.66，95%CI （0.50，6.82），P=0.02〕，and more hospitalization expenses〔WMD=503.96，95%CI （337.23，670.70），P＜0.000 01〕.But there were no significant differences in hospitalization time〔WMD=-0.11，95%CI （-3.64，3.43），P=0.95〕 and incidence rate of peritoneal abscess 〔OR=1.40，95%CI （0.23，8.64），P=0.71〕 between laparoscopic and open appendectomy. Conclusions The wound infection rate is lower，but the operation time is longer，the hospitalization expenses is more in laparoscopic appendectomy as compared with open appendectomy. There are no statistically significant differences of hospitalization time and incidence rate of abdominal abscess between laparoscopic and open appendectomy.
目的总结腹腔镜阑尾切除术(laparoscopic appendectomy，LA)的应用经验。方法回顾性分析我院2009年5月至2010年8月期间153例行LA手术患者的临床资料。结果153例中男74例，女79例; 年龄8～76岁，平均32.5岁。其中慢性阑尾炎7例，急性单纯性阑尾炎41例，急性化脓性阑尾炎81例，急性坏疽穿孔性阑尾炎24例。149例在腹腔镜下顺利完成手术，4例因阑尾周围组织水肿及粘连明显、镜下解剖不清而中转开腹。手术时间30～90 min，平均51 min。住院时间3～8 d，平均5 d。发生脐部戳孔感染5例。随访1～12个月（平均5个月），无术后出血、腹腔脓肿及粘连性肠梗阻发生。结论LA创伤小，疤痕小，恢复快，住院时间短，并发症少，安全性高。
目的 探讨隐蔽三孔法腹腔镜阑尾切除术的应用。方法 患者取头低左侧卧位。在脐缘切口插入10 mm的套管，放入腹腔镜。在腹腔镜监视下分别于耻骨结节左、右侧阴毛生长区作10 mm、5 mm切口，两切口相距8~10 cm。术者通过耻骨上途径完成阑尾切除操作。结果 192例痊愈出院，无一例手术中转，平均手术时间（25±4.32） min，平均住院时间（5±0.79） d。切口甲级愈合，基本不留疤痕。无手术并发症发生。结论 隐蔽三孔法腹腔镜阑尾切除术具有美容效果好、创伤小、并发症少等优点。
ObjectiveTo compare the outcomes of laparoscopic appendectomy (LA) and open appendectomy (OA) for the acute appendicitis patients based on our extensive experiences. MethodsThe data of all the acute appendicitis patients who underwent appendectomy from January 2013 to December 2014 in our department were retrospectively reviewed. A total of 201 patients were enrolled and divided into LA group (n=102) and OA group (n=99). The relevant clinical indexes during and after operation of two groups were compared. ResultsThere were no significant difference in age, gender, and underlying disease between LA and OA patients (P > 0.05). And the abdominal cavity infection rate, abdominal drainage rate and 30-day readmission rate were also similar (P > 0.05). But LA group had less operative time, lower infection operative wound rate, less intestinal function recovery time, shorter inhospital days and higher hospital expenses than OA group (P < 0. 05). In addition, perforated appendix and LA could increase the rate of abdominal drainage[OR=2.710, 95% CI(1.129, 6.507), P=0.026]. ConclusionsBoth LA and OA are safe and effective methods for the treatment of acute appendicitis. But LA has several advantages over OA on less operative time and postoperative complications, earlier recovery, and shorter inhospital days. While LA have higher hospital cost than OA, it still should be considered as a prefer way to cure acute appendicitis. LA is a independent risk factor of abdominal drainage.