west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "苏晨" 2 results
  • Off-label Use of Aspirin in Outpatients of Sun Yat-sen Memorial Hospital in 2013: A Retrospective Survey

    ObjectiveTo understand the situation of off-label use of aspirin among outpatients in Sun Yatsen Memorial Hospital, so as to provide baseline data for developing off-label drug use policy. MethodsA stratified random sampling method was used to collected prescription data of aspirin among outpatients in 2013. The incidence rates between different types of off-label use of aspirin were determined by chi-square test, and the influence factors of off-label drug use were analyzed by logistic regression model. ResultsA total of 5 023 prescriptions with aspirin were collected and analyzed, with incidence rate of off-label use up to 17.7%. The major category of off-label use was no indication (94.38%). The top 3 no indications were recurrent abortion, infertility and systemic lupus erythematosus. Drug specification, gender, age and prescribed department were the risk factors of off-label use. ConclusionAspirin off-label use is common among outpatients in Sun Yat-sen Memorial Hospital in 2013, especially in obstetrics and gynecology department and assisted reproductive center. The results suggest that more clinical studies about aspirin for reproduction are needed to provide more evidence of drug use, so as to ensure the safety of drug use in special populations and avoid potential medical risk.

    Release date: Export PDF Favorites Scan
  • 纳米炭染色结直肠癌淋巴结分站对比研究

    目的探究纳米炭染色对结直肠癌淋巴结示踪的规律以及对转移淋巴结检出的影响。方法回顾性收集2022年4月至2023年9月期间于重庆医科大学附属第一医院胃肠外科接受腹腔镜结直肠癌根治性手术及术前行肿瘤纳米炭标记的92例患者的标本。新鲜标本淋巴结按第一站、第二站及第三站分检,各站又分为染色组和未染色组。比较各组间及组内不同站不同染色程度淋巴结的差异。结果共纳入92例患者,共分检出淋巴结2 859枚,其中转移淋巴结66枚(2.3%),未转移2 793枚(97.7%);黑染淋巴结2 167枚(75.8%),未染色692枚(24.2%)。淋巴结染色率从第一到第三站逐渐递增(P<0.017);第一站和第二站转移淋巴结的染色率比同站所有淋巴结染色率低(χ2=23.959,P<0.001;χ2=7.187,P=0.007),但在第三站中差异无统计学意义(χ2=1.155,P=0.283);第一站和第二站染色淋巴结转移率小于未染色淋巴结(χ2=26.224,P<0.001;χ2=7.520,P=0.006),但第三站中差异无统计学意义(χ2=1.232,P=0.267)。结论纳米炭淋巴结示踪效果随着淋巴回流逐渐增强。在第一站和第二站,其对于转移淋巴结的显示缺乏特异性,手术及分检过程中应更关注未染色淋巴结。在第三站淋巴结中,能够更有效地示踪转移淋巴结,可按染色淋巴结进行针对性地淋巴结清扫。

    Release date: Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content