west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "蔡逊" 7 results
  • 上皮钙粘附蛋白和CD44v6在肝外胆管癌和胆总管囊肿组织中的表达及临床意义

    Release date:2016-08-28 04:43 Export PDF Favorites Scan
  • 内环填塞式腹股沟疝不缝合修补手术

    Release date:2016-08-29 09:18 Export PDF Favorites Scan
  • 胆囊十二指肠瘘18 例临床诊治分析

    Release date:2016-09-08 10:37 Export PDF Favorites Scan
  • Establishment and Evaluation of Type 2 Diabetes SD Rat Model

    ObjectiveTo evaluate the influencing factors and explore a better method of making rat model of type 2 diabetes by high fat and sugar diet and streptozotocin(STZ) injection. MethodsSixty SPF grade of 6 weeks male SD rats were fed with high fat and glucose diet by 4 weeks and then randomly divided into 3 groups, the control group rats(n=20) were injected citric acid by 50 mg/kg and fed with normal diet, and the diabetes mellitus group rats were further divided into 2 subgroups by the different doses of STZ:the rats of diabetes mellitus model group 1(n=20) were injected by 50 mg/kg, while the rats of diabetes mellitus model group 2(n=20) were injected by 35 mg/kg. The diabetes mellitus model group rats were fed with high fat and glucose diet continually. The fasting blood glucose(FBG) were measured on day 3, 7, 10, and 14, respectively. The success model rate(blood glucose > 16.7 mmol/L after 14 days) and the mortality rate were calculated. Meanwhile fasting serum insulin level(FSI), total serum cholesterol(TC), and triglyceride(TG) were measured. ResultsCompared with the control group, the levels of FBG, FSI, TC, and TG were increased significantly in the diabetes mellitus model group 1 and 2(P < 0.05). And insulin sensitivity was worsen markedly(P < 0.05). But the diabetes mellitus model group 2 had higher success rate of making model(85% vs. 75%) and lower mortality(0 vs. 25%), P < 0.05. ConclusionRat model of type 2 diabetes induced by 4 weeks of high fat and sugar feeding and 35 mg/kg STZ injection has high morbidity, strongly security, and stable features.

    Release date: Export PDF Favorites Scan
  • Comparative Study of Short-Term Outcomes Between Total Laparoscopic Gastrectomy and Laparoscopy-Assisted Gastrectomy for Gastric Cancer

    ObjectiveTo compare clinical efficacy of totally laparoscopic gastrectomy (TLG) and conventional laparoscopy-assisted gastrectomy (LAG) and to explore safety and feasibility of total laparoscopic anastomosis in laparoscopic gastrectomy. MethodThe clinical data of 64 patients who received TLG and another 70 patients who received conventional LAG in our department from January 2013 to March 2014 were retrospectively analyzed. ResultsAll procedures were completed successfully. There were no significant differences in the time of anastomosis〔(73.8±10.3) min versus (72.7±8.9) min, t=0.693, P=0.489〕 and the number of dissected lymph nodes (32.4±9.7 versus 33.6±9.6, t=-0.700, P=0.485) between the patients underwent TLG and the patients underwent LAG. However there were obvious differences in the blood loss〔(275.0±66.3) mL versus (364.3±75.7) mL, t=-7.419, P=0.000〕, the incision length〔(3.0±0.8) cm versus (7.3±1.7) cm, t=-19.354, P=0.000〕, the time to fluid diet〔(4.9±0.8) d versus (6.0±0.7) d, t=-8.750, P=0.000〕 and the time to flatus 〔(2.8±0.8) d versus (3.9±0.8) d, t=-8.388, P=0.000〕, the off-bed time〔(1.3±0.5) d versus (3.4±1.2) d, t=-14.118, P=0.000〕, and the hospital stay〔(9.8±1.2) d versus (13.0±1.5) d, t=-17.471, P=0.000〕 between the patients underwent TLG and the patients underwent LAG. Meanwhile it was found that the postoperative pain score〔On day 1 postoperatively: (3.4±0.8) points versus (6.2±1.3) points, t=-15.509, P=0.000; on day 3 postoperatively: (1.7±0.6) points versus (4.0±0.8) points, t=-18.799, P=0.000〕 and the dosage of pain killers (1.7±0.7 versus 4.0±2.1, t=-8.912, P=0.000) in the patients underwent TLG were significantly lower than those in the patients underwent LAG. One patient developed anastomotic leakage and 3 patients developed anastomotic stenosis in the patients underwent LAG, the complication rate related to the anastomosis was 5.7% (4/70). While there were no complications related to the anastomosis in including anastomotic leakage, stenosis, and bleeding in the patients underwent TLG. ConclusionsTotal laparoscopic anastomosis is safe and feasible in laparoscopic gastrectomy for gastric cancer. Compared with small incision-assisted anastomosis, totally laparoscopic anastomosis is associated with minimal trauma, less blood, quicker postoperative recovery, shorter time, slighter pain and satisfactory short-term efficacy.

    Release date: Export PDF Favorites Scan
  • Laparoscopy Combined with Choledochoscopy in Treatment of Schistosomiasis Liver Cirrhosis with Common Bile Duct Stone

    ObjectiveTo summarize experience of laparoscopy combined with choledochoscopy common bile duct exploration for patients with schistosomiasis liver cirrhosis with common bile duct stones. MethodThe clinical data of 45 patients with schistosomiasis liver cirrhosis combined with common bile duct stones (liver function Child-Pugh grade A and B) admitted in this hospital from September 2012 to September 2015 were analyzed retrospectively. ResultsTwenty cases were successfully treated by laparoscopy combined with choledochoscopy (laparoscope group), 25 cases were treated by conventional open common bile duct exploration (laparotomy group). Two cases were converted to laparotomy due to bleeding during laparoscopic operation. The mean operation time, intraoperative bleeding, postopera-tive hospitalization time, and postoperative total complications rate had no significant differences between these two groups (P>0.05). There were 2 cases of pulmonary infection and 1 case of incision infection in the laparoscope group, and 1 case of grade A bile leakage and 1 case of pulmonary infection in the laparotomy group, there was no common bile duct stone residual in these two groups. ConclusionAlthough laparoscopic surgery is more difficult for schistosomiasis liver cirrhosis combined with common bile duct stones patients, it is safe and feasible. Appropriate perioperative management and precise laparoscopic and choledochoscopic operation are key to success of operation.

    Release date:2016-11-22 10:23 Export PDF Favorites Scan
  • 急性非结石性胆囊炎的综合诊治分析

    目的 探讨急性非结石性胆囊炎(AAC)的临床特点、诊断及治疗方法。 方法 对 2010 年 10 月至 2016 年 8 月期间笔者所在医院收治的 56 例急性非结石性胆囊炎患者的相关临床资料进行回顾性分析。 结果 56 例患者均施以外科治疗。44 例患者行手术治疗,其中行开腹胆囊切除手术 10 例;腹腔镜胆囊切除手术(LC)34 例,其中有 6 例中转开腹手术,全部手术患者均病情恢复良好,无重大并发症发生。另 12 例患者行经皮经肝胆囊穿刺置管引流术(PTGD)治疗,其中 8 例患者 4 周后行 LC;4 例患者症状缓解 4 周后拔除胆囊穿刺管,拒绝手术治疗,其中 3 例患者于拔管后 4~6 周复发 AAC,急诊行 LC,另 1 例患者 AAC 未复发。 结论 彩超、CT、血生化检验及临床表现是早期诊断急性非结石性胆囊炎的主要方法。外科手术是防止胆囊穿孔、降低并发症和死亡率的重要措施。早期(尤其是发病后 72 h 内)行腹腔镜胆囊切除术是安全、可行的。PTGD 可作为 AAC 高危患者的一种安全、有效的急诊处置手段,可为危重患者病情恢复创造条件,为择期手术赢得机会。

    Release date:2017-07-12 02:01 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content