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find Author "袁宝强" 2 results
  • 癫痫患儿停药后复发影响因素的研究进展

    癫痫是一种脑部疾患,其特点是持续存在能导致癫痫发作的脑电改变,并出现相应的神经生物学、认知、心理学以及社会等方面的后果。经合理治疗后,大多数患儿的发作是可以控制的。癫痫缓解后可以考虑减停药物,但在减停药物的患儿中仍有 12%~67% 的复发风险。国内外就影响癫痫患儿复发的因素尚未达成共识。文章从可能影响癫痫患儿复发的因素方面进行综述,以期对儿童神经科医生指导患儿减停药物有所帮助,从而将复发率降至最低。

    Release date:2020-05-19 01:07 Export PDF Favorites Scan
  • Analysis of risk factors for relapse of 133 epileptic children after withdrawal of drugs

    ObjectiveThe risk factors of relapse in 133 epileptic children after withdrawal were analyzed retrospectively and provide reference for clinical withdrawal.MethodsFrom January 2017 to March 2019, 133 children with withdrawal epilepsy were selected as the study object. According to whether there was recurrence during the follow-up period, the children with epilepsy were divided into recurrence group (42 cases) and non recurrence group (91 cases). The gender, age of onset, history of trauma, frequency of seizure before treatment, EEG before drug reduction, imaging, type of medication, family history, time of reaching control, course of disease before treatment, comorbidity, multiple attack types, withdrawal speed and EEG before treatment were observed and compared between the two groups. ResultsThere were significant differences in EEG (χ2 =7.621), medication type (χ2=8.760), time to control (χ2=6.618), course before treatment (χ2=6.435), multiple seizure types (χ2=5.443) and epilepsy comorbidity (χ2=42.795) between the two groups (P < 0.05). The results of Logistic multiple regression analysis showed that the recurrence of epileptic children after drug reduction / withdrawal was correlated with abnormal EEG before drug reduction [OR=9.268, 95%CI (2.255, 38.092)], combined drug treatment [OR=3.205, 95%CI (1.159, 8.866)] and course of disease > 1 year before treatment [OR=5.363, 95%CI (1.781, 16.150)] (P < 0.05).ConclusionsIn order to reduce the possibility of recurrence of epileptic children, the treatment time of epileptic children with abnormal EEG, combined medication and long course before treatment should be prolonged properly.

    Release date:2020-07-20 08:13 Export PDF Favorites Scan
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