west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "覃宇周" 2 results
  • INVESTIGATION OF PREOPERATIVE AND POSTOPERATIVE SERUM SOLUBLE INTERLEUKIN-2 RECEPTOR IN PATIENTS WITH BREAST CANCER

    To investigate the relationship between the serum soluble interleukin-2 receptor (sIL-2R) and the stage and prognosis of breast cancer. Using the method of sandwich ELISA, the preoperative and postoperative sIL-2R in 37 cases of breast cancer was measured, 13 patients with benign disease of breast and 40 normals were also measured. The serum sIL-2R levels in patients with breast cancer were significantly higher than that of the benign disease of breast and the normal controls. The serum sIL-2R about twenty days after operation was significantly lower than that before operation. The sIL-2R in patients with breast cancer was correlative to the clinical stage. The serum sIL-2R in stage Ⅲ patients was remarkly higher than both stage Ⅰ and Ⅱ, its sIL-2R about twenty days after operation remained in a high level. This results showed that expression of the serum sIL2R is correlative to the clinical stage and prognosis of the patients with breast cancer, it can be used as a marker of differentiating the benign from malignant disease of breast.

    Release date:2016-08-29 09:20 Export PDF Favorites Scan
  • 乳腺癌患者手术前后血浆可溶性P选择素的检测及意义△

    可溶性P选择素可抑制多形核中性粒细胞通过整合素CD11b与血管内皮细胞粘附,有明显的控制炎症的作用[1],也可介导某些肿瘤细胞与内皮细胞的粘附[2],与肿瘤的发展和转移有关。为探讨血浆可溶性P选择素水平在乳腺癌患者手术前后的变化及意义,我们检测了42例乳腺癌患者手术前后血浆可溶性P选择素水平,现报道如下。1资料与方法正常对照组36例,男女各18例,年龄23~55岁,平均37.6岁,系健康体检者,于早晨取空腹静脉血。乳腺癌组42例,年龄27~68岁,平均47.6岁,均为临床Ⅱ期患者,并行根治性手术,其中行乳腺癌根治术15例,乳腺癌改良根治术27例。组织学类型: 单纯癌29例,浸润性导管癌5例,髓样癌3例,硬癌3例,粘液腺癌2例。分别于术前1 d、术后第1 d、15 d和30 d早晨取空腹静脉血,应用可溶性P选择素ELISA试剂盒(苏州医学院血栓病研究所提供)检测血浆可溶性P选择素。所得数据用±s表示,用t检验和方差分析进行组间比较。

    Release date:2016-08-28 05:10 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content