Objective To observe the retinal function of infa nts with retinopat hy of prematurity (ROP). Methods A total of 78 infants (156 ey es) aged from 4-5 months underwent full-field flash electroretinogram (ERG) examination. The am p litude and implicit time of a-and b-wave of ERG were detected to evaluate the i nfants' retinal function. Seventy-eight infants (156 eyes) included 33 healthy a nd full-term infants (66 eyes), 25 healthy premature children (50 eyes), and 20 infants (40 eyes) with ROP. Results Obvious ERG waveforms were recorded in all the fullterm and healthy premature children. Amplitude of combined b-wave wa s 388.7 mu;V in full-term infants and 336.7 mu;V in healthy premature children, whi c h was 64.4% and 55.6% of that of the healthy adults respectively. In infants wit h ROP, ERG was nonrecordable in 20 eyes (50％); amplitude of combined b-wave was 183.8 mu;V in the other 20, whose implicit time delayed obviously compared with that of fullterm infants. The amplitude of ERG of healthy premature infants de c reased significantly compared with that of the full-term infants. Conclusions Retina keeps growing after birth. ERG of healthy full-term chi ldren is not as developed as those of adults. The progress of retinal maturation in infants with ROP is slower than that in the full-term infants. ERG examination is an effecti ve method in evaluating retinal function of infants with ROP.
Objective To explore the changes of multifocal electroret inogram (mERG) before and after retinal detachment surgery and its clinical significance. Methods Eighteen patients suffered from rhegmatogen ous retinal detachment underwent mERG before and after surgery using VERIS ScienceTM 4.0. The mERG at different area was compared between preoperative and postope rative surgery. Results Preoperatively, the latencies of a wave and b wave in detached area were statistically longer than in attached area (t=4.541 and 6.784, Plt;0.01). The amplitude densities of a wave and b wave were statistically smaller in detached area than in attached area (t=3.680 and 4.257, Plt;0.01). Postoperatively, the amplitude densities of a wave and b wave at fovea, macula, perimacular area and whole tested area significantly improved. Statistical difference was found before and after surgery, but no statistical difference was found in the latencies of a wave and b wave. The amplitude densities of a wave and b wave in the preoperative detached area were statistically larger after surgery than before surgery (Plt;0.05). Conclusions After retinal detachment surgery, the responses of mERG improve to some degree. mERG was a promising tool to evaluate the recovery of retinal function after surgery . The amplitude densities are more sensitive than the latencies to evaluation of retinal function. (Chin J Ocul Fundus Dis, 2001,17:264-267)