west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "视野" 78 results
  • Clinical features and visual function of recurrent neuromyelitis optica

    Objective To observe the clinical features and visual function of recurrent neuromyelitis optica (NMO). Methods Thirty-four patients with NMO were enrolled in this retrospective case series study. The patients included two males and 32 females. The average first onset age was (35.03plusmn;14.56) years old and the average recurrent rate were (4.24plusmn;2.45) times. The recurrent rate of optic neuritis (ON) ranged from two to 12 times. The recurrent rate of ON was two times in 15 eyes of 10 patients, ge;three times in 37 eyes of 24 patients. Vision acuity, direct ophthalmoscope, fundus pre-set lens examination, visual field and visual evoked potential (VEP) were evaluated. Clinical features were observed. The abnormal rate of optic nerve including optic edema and atrophy; abnormal rate of visual field including decreasing retinal sensitivity, central and paracentral scotoma, ring scotoma, half field defects, tunnel visual field, visual field centrality constriction; abnormal rate of VEP including Prolonged latent phase and/or decreasing amplitude of P100 wave from patients of first episode or recurrence was analyzed. Serum NMO-IgG was detected from 28 patients by indirect immunofluorescence technique to observe its positive rate. Results All patients were characterized by repeated episodes of ON and myelitis. The main clinical feature of ON was visual loss, and the main clinical features of myelitis included sensory disability, dyskinesia and vesicorectal disorder. Blindness rate was 41.67% after the first attack of ON, 33.33% after two relapses, and 64.86% after ge; three relapses. The difference of blindness rate between first attack and two episodes was not significant (chi;2=0.270,P=0.603). However, the blindness rate in patients having ge; three episodes was significantly higher than those having two episodes (chi;2=4.300,P=0.038). With recurrence rate increasing, the abnormal rate of the optic nerve (chi;2=6.750,P=0.034)and VEP(chi;2=6.990,P=0.030)increased. But the abnormal rate of visual field did not increase along with recurrent rate (chi;2=0.660,P=0.718). Seropositive rate of NMO-IgG did not differ significantly between patients with first attack ON and that with recurrent ON (chi;2=1.510,P=0.470). But the seropositive patients had significantly higher bilateral blindness rate than seronegative patients (chi;2=5.063,P=0.027). Conclusions NMO are characterized by recurrent ON and myelitis. Visual loss, sensory disability, dyskinesia and vesicorectal disorder are the main clinical features. With recurrence rate increasing, the blindness rate, abnormalities the optic nerve and the abnormity rate of VEP increase. Seropositive recurrent NMO patients have higher bilateral blindness rate than seronegative patients.

    Release date:2016-09-02 05:22 Export PDF Favorites Scan
  • 关于向本刊投稿的方式及注意事项说明

    本刊网站于2006年底改版开通时即使用北京玛格泰克科技发展有限公司开发的稿件远程处理系统实现了全部稿件处理流程的远程在线管理。为了保持稿件处理及信息管理的连续性,在中华医学会杂志社网站稿件远程管理系统完善并正式上线之后本刊未行更换,仍然使用其原有的稿件处理系统进行稿件管理。所以,向本刊投稿均请通过本刊网站“眼底病论坛”(www.coretina.com)实行网上投稿。投稿时请登陆本刊网站,至《中华眼底病杂志》窗口,在左侧点击“作者区”,进入注册后完成投稿流程。由于以电子邮件方式投稿后仍然要通过上述方式上传文档后才能通过稿件远程处理系统进入外审流程,所以请勿以电子邮件方式投稿。谢绝以邮寄纸质文本的方式投稿。需要提请作者投稿时注意的问题是:(1)本刊不收稿件处理费。通过同行评议并决定刊用的文稿,再按有关规定,另行通知收取适当的版面费。(2)论文推荐信及授权书必须具备。论文推荐信和授权书统一使用中华医学会系列杂志论文投送介绍信及授权书,此介绍信及授权书可在本刊网站杂志首页下载,所有作者亲笔签名,负责人签字并加盖单位公章。如涉及保密问题,需附有关部门审查同意发表的证明。(3)稿件中涉及医学伦理问题及知情同意者,还应提供人体试验的委员会(单位性的、地区性的或国家性的)的标准文件及受试对象或其亲属的知情同意书。(4)属于各种基金资助的研究项目,应提供基金资助批复证明的复印件。论文投送介绍信及授权书、知情同意书、基金资助证明复印件在完成网上投稿后另寄至编辑部。我刊接受作者查询稿件的Email地址为coretina@163.com。

    Release date:2016-09-02 05:22 Export PDF Favorites Scan
  • Characteristics of fundus autofluorescence in primary retinitis pigmentosa and its relationship with visual fields

    Objective To observe the characteristics of fundus autofluorescence (AF) in short wavelength AF (SW-AF) and Near Infrared AF (NIR-AF), and their relationship with visual fields. Methods Twelve patients (24 eyes) with primary RP were enrolled in this study. The patients included nine males (18 eyes) and three females (six eyes). The patients aged from 15 to 69 years, with a mean age of (35.33plusmn;15.03) years. All the patients were examined for color photography, SW-AF, NIR-AF, visual fields and optical coherence tomography examination. Results There were hyper-AF ring of varying sizes in posterior pole by SW-AF and NIR-AF examinations. The area of hypo-AF which located in SW-AF hyper-AF ring had a positive correlation with the area of hyper-AF in the NIR-AF (r=0.662,P<0.05). OCT showed that outside the hyper-AF ring, there were disconnected inner segment/outer segment (IS/OS) junction and external limiting membrane, and thinned outer nuclear layer and retinal pigment epithelium. Peripheral retinal osteocytes-like pigmentation showed non fluorescence in SW-AF and NIR-AF. The plaque-like area showed mottled and low fluorescence examined by SW-AF. SW-AF hyper-AF ring had a positive correlation with visual fields (r=0.492,P<0.05). Conclusions The area of hypo-AF inside of the SW-AF hyper-AF ring is related to visual fields in RP patients. The retinal structures in the hypo-AF area inside of the SW-AF hyper-AF ring, and in the NIR-AF hyper-AF region are normal.

    Release date:2016-09-02 05:22 Export PDF Favorites Scan
  • 特发性黄斑裂孔手术前后视功能的MP-1微视野检查

    Release date:2016-09-02 05:26 Export PDF Favorites Scan
  • 黄斑区脉络膜新生血管患眼光动力疗法治疗前后黄斑结构和功能的光相干断层扫描联合微视野检查

    Release date:2016-09-02 05:26 Export PDF Favorites Scan
  • 重视视力性质分析,增强视功能评价相关临床研究的科学性:与“甲钴胺联合糖皮质激素治疗视神经炎74例临床疗效观察”一文作者商榷

    编者按 视力性质的认识、判断、分析涉及眼科基础和临床研究的层面较多,本期刊发夏德昭教授针对这一问题提出的商榷一文,就是希望读者、作者在临床和研究工作中就此问题引起更多关注和重视,以进一步增强与视功能评价相关研究工作的科学性。

    Release date:2016-09-02 05:26 Export PDF Favorites Scan
  • Analysis of visual field in nonarteritic anterior ischemic optic neuropathy

      Objective To study the visual field defects and its correlation factors in nonarteritic anterior ischemic optic neuropathy (NAION). Methods One hundred and thirty-nine patients of NAION with complete visual field examination results were included in this study. There were 65 males (46.7%)and 74 females (53.3%),with an average age of (56.2plusmn;10.8) years. All the patients had undergone the examinations of visual acuity,refraction,refractive media, slit lamp ophthalmoscope, color fundus photography, visual field, blood pressure, blood routine test and blood biochemistry test. Fundus fluorescein angiography (FFA) was carried out in 125 patients. The visual field characteristics and its correlation factors were statistically analyzed, and the FFA and visual field results of 77 eyes were comparatively analyzed. Results The visual field examination showed typical inferior defect in 48 eyes (34.5%), arcuate scotoma in 24 eyes (17.3%), atypical arcuate scotoma in 24 eyes (17.3%), defuse defect in 20 eyes (14.4%), superior defect in 10 eyes (7.2%), superior defect with inferior arcuate scotoma in five eyes (3.6%), inferior defect with superior arcuate scotoma in eight eyes (5.8%). The mean defect (MD)value ranged from -3.0 to -32.0,with an average of -17.9plusmn;7.9. Among 77 eyes with FFA data, the FFA and visual field defect area were highly consistent seven eyes (9.1%), consistent in 26 eyes (33.8%), some kind of consistent in 39 eyes (50.6%), completely inconsistent in five eyes (6.5%). Multiple lineal regression analysis showed that mean red cell volume (MCV) (beta;=0.203,t=2.005) and cholesterol level (CHOL) (beta;=0230,t=2.244) were correlation factors of MD (P<0.05). Conclusion The visual field defect of NAION shows a variety of patterns which may be mainly influenced by MCV and CHOL.

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • Fixation features of foveoschisis in pathological myopia

      Objective To observe the fixation features of foveoschisis in pathological myopia patients. Methods 36 patients (42 eyes) with gt;6.00 D myopic degree and foveoschisis who diagnosed by optical coherence tomography were included. The patients were divided into foveoschisis with retinal detachment group (11 eyes), foveoschisis with macular hole group (12 eyes) and only foveoschisis group (19 eyes). Micro-perimeter MP-1 was used to identify the fixation location and fixation stability. Results The eccentric fixation were formed above the fovea in the foveoschisis with retinal detachment and foveoschisis with macular hole group, the fixation location was formed on fovea in the only foveoschisis group. The fixation stability of the foveoschisis with retinal detachment, foveoschisis with macular hole and only foveoschisis group were (23plusmn;4)%,(59plusmn;6)%,(91plusmn;11)% respectively, the difference was statistically significant (F=243.47,P<0.01). Conclusions The fixation location is formed on fovea in the patients with foveoschisis in pathological myopia. The eccentric fixation is formed above the fovea in the patients who has foveoschisis with retinal detachment and macular hole in pathological myopia.

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • Macular function of pathologic myopic retina evaluated by microperimetry

      Objective To observe the microperimetry performance of macular function in pathologic myopia patients. Methods The clinical data of 90 patients (142 eyes) with pathologic myopia were retrospectively analyzed. All patients were asked in details about history, and take examinations of best corrected visual acuity (BCVA), refractive dioptre, eye axis, fluorescent fundus angiography (FFA), indirect ophthalmoscopy and optical coherence tomography (OCT). According to the test results, patients were divided into non-pathological macular group (20 patients, 24 eyes) and pathological macular group (70 patients, 118 eyes). Retinal imaging and macular microperimetry were measure by MP-1 Microperimeter.The mean retinal sensitivities (MS) and fixation stability in the central 10deg;, fixation rate and fixation position in the central 2deg; and 4deg;were determined.Results The MS of pathological and non-pathological macular group were(16.39plusmn;2.12), (10.80plusmn;4.53) dB respectively, the difference was statistically significant(F=15.044,t=-9.314;P=0.000). Among 24 eyes of non-pathological macular group, fixation was stable in 19 eyes (79.17%), relative unstable in five eyes (20.83%); among 118 eyes of pathological macular group, fixation was stable in 45 eyes (38.14%), relative unstable in 52 eyes (44.07%), unstable in 21 eyes (17.79%), the difference was statistically significant(chi;2=13.56, P=0.000). The differences of 2 deg;and 4 deg;fixation rate between those two groups are statistically significant (F=5.773, 13.230; t=-4.110,-5.465;P=0.000) . Among 24 eyes of non-pathological macular group, center fixation occurred in 23 eyes (95.83%), weak center fixation occurred in one eye (4.17%); among 118 eyes of pathological macular group, fixation center occurred in 81 eyes (68.64%), weak center fixation occurred in 16 eyes (13.56%),eccentric fixation occurred in 21 eyes (17.80%), the difference was statistically significant (F=9.618,t=-5.773;P=0.000).Conclusion Pathological myopia patients with pathological macular changes have decreased retinal sensitivity, decreased fixation stability and eccentric fixation points.

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • Ophthalmoscopic image characteristics and relation with vision and course of disease in nonarteritic anterior ischemic optic neuropathy

      Objective To observe the characteristics of fundus fluorescein angiography(FFA)and optical coherence tomography(OCT)in nonarteritic anterior ischemic optic neuropathy (NAION),and investigate its relation with visual acuity and course of disease.Methods The clinical data of 47 patients (47 eyes) with NAION were retrospectively analyzed. All the patiens had undergone visual acuity,fundus and visual field examination,meanwhile FFA and OCT were carried out at first visit. FFA and visual field were carried out by routine. OCT was carried out by line and circle shape scanning in macula and optic disc. Thirtyfive NAION patients were checked with OCT at half, one, two, three and six month after onset in respectively. Take the healthy fellow eyes of 36 NAION patiens as control group.The FFA,visual field,OCT characteristics and relation with visual acuity and course disease were comparatively analyzed.ResultsFFA showed that all the eyes appear as delayed filling of the optic disc in early stage and hyperfluorescence leakage of the optic disc in late stage,besides hyperfluorescence presented to macular area in 24 eyes. OCT showed that optic papilla swelling and physiological depression narrow or nearly disappearance, neuroepithelial layer thickening or neuroepithelial layer eminence and subretinal fluidity area opaca between optic disc and macula. There were 14 eyes with normal physiological depression and 22 eyes with small physiological depression or non physiological depression in control group. Half month after onset,the neuroepithelial layer thickness of macula fovea, the maximum thickness of neuroepithelial layer between optic disc and macula,and the average retinal nerve fiber layer(RNFL)thickness in NAION group were higher than those in the control group,the difference were statistically significant (F=6.51,26.12,75.49;P<0.05).Two months after onset,the maximum thickness of neuroepithelial layer between optic disc and macula, the average RNFL thickness, and the RNFL thickness of temporal optic disc in NAION group were significant thinner, but the elevated height of the optic disc in NAION group were near those of the control group. Three months after onset,the average RNFL thickness and the RNFL thickness of temporal optic disc in NAION group decreased continually, they were lower than those of the control group, the difference were statistically significan(F=75.49,37.92;P<0.05).Visual field showed that inferior defect were found in 21 eyes (45%). With progress, the superior RNFL thickness obviously decreased, coincidence with appearance of visual field. It indicate that the superior optic atrophy serious. Visual acuity had significant negative correlation with the neuroepithelial layer thickness of macula fovea, the neuroepithelial layer maximum thickness between optic disc and macula, the average RNFL thickness, the RNFL thickness of temporal optic disc(r=-0.394,-0.424,-0.412,-0.464;P<0.05).Conclusions FFA showes that hyperfluorescence leakage appearanced in part macula. OCT showes that RNFL becomes thinner as the disease duration increases. The results of OCT and visual field examinaion in the configuration of optic disc and changes of RNFL are accordant.

    Release date:2016-09-02 05:41 Export PDF Favorites Scan
8 pages Previous 1 2 3 ... 8 Next

Format

Content