目的 对比A型超声角膜测厚仪、OrbscanⅡ眼前节分析仪和Pentacam眼前节分析仪测量准分子激光原位角膜磨镶术（LASIK）前后中央角膜厚度的差异。 方法 2010年10月－2011年3月，分别使用A型超声角膜测厚仪、OrbscanⅡ和Pentacam眼前节分析仪测量137例（274只眼）近视患者LASIK前后中央角膜厚度，并对测量结果进行配对t检验和Pearson相关性分析。 结果 LASIK术前A型超声、OrbscanⅡ和Pentacam测量值分别为（526.6 ± 34.1）、（516.6 ± 34.2）、（539.8 ± 31.5） μm，Pentacam测量值较A型超声和OrbscanⅡ测量值高，差异有统计学意义（P＜0.05），而A型超声和OrbscanⅡ测量值之间差异无统计学意义（P＞0.05）；LASIK术后6个月A型超声、OrbscanⅡ和Pentacam测量值分别为（448.2 ± 48.5）、（391.9 ± 58.5）、（451.5 ± 46.4） μm，LASIK术后A型超声和Pentacam测量值无差异（P＞0.05），而OrbscanⅡ测量值较A型超声和Pentacam低；Pearson相关分析显示，LASIK术后Pentacam和A型超声CCT测量值呈高度相关（P＜0.05）。 结论 3种仪器的中央角膜厚度测量值不可互换，LASIK术后A型超声和Pentacam量值较为准确。Objective To compare the difference in measurements of central corneal thickness (CCT) using A-scan, OrbscanⅡand Pentacam before and after laser in situ keratomileusis (LASIK). Methods Between October 2010 and March 2011, the CCT of 137 patients (274 eyes) were measured by A-scan, OrbscanⅡ and Pentacam, and the results were analyzed by paired t-tests and Pearson correlation. Results Before LASIK, the values of CCT measured by A-scan, OrbscanⅡ and Pentacam were (526.6 ± 34.1), (516.6 ± 34.2), and (539.8 ± 31.5) μm respectively; paired t-tests showed the CCT values obtained with Pentacam were significantly higher than those with other methods (P＜0.05), but there were no statistical significant differences between OrbscanⅡand Pentacam measurements (P＞0.05). Six months after LASIK, the values of CCT measured by A-scan, OrbscanⅡand Pentacam was (448.2 ± 48.5), (391.9 ± 58.5), and (451.5 ± 46.4) μm respectively; the CCT values obtained with A-scan and Pentacam didn’t differ much from each other (P＞0.05), and the CCT values obtained with OrbscanⅡwere lower than those obtained with A-scan and Pentacam. There was a high correlation between A-scan and Pentacam measurements. Conclusion The these methods measuring CCT could not be used interchangeably, and A-scan and Pentacam after LASIK were more precise than OrbscanⅡ.
目的:探讨高龄白内障患者术前角膜内皮功能状态。方法:对从2007年11月到2008年10月的66例年龄在80岁或以上的左眼白内障患者术前角膜内皮细胞形态及中央角膜厚度进行回顾性分析。分析参数包括角膜内皮细胞密度,内皮细胞平均面积,最大细胞面积和最小细胞面积,内皮细胞变异系数,面积标准差,六角形细胞比例及角膜中央厚度。结果:患者的角膜内皮细胞平均密度为(2720.3±324.6)个/mm2,平均细胞面积为(375.4±70.3)μm2,最大细胞面积(922.1±243.5)μm2,最小细胞面积(131.2±40.2)μm2,面积标准差(143.5±34.8)μm2,细胞变异系数(38.0±7.3)%,六角形细胞比例(52.8±10.1)%。中央角膜厚度与角膜内皮细胞密度之间无相关性。结论:高龄人白内障患者的角膜内皮细胞密度高,角膜功能基本正常，是保持角膜透明的基础,为眼内手术或治疗提供安全保障。