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find Author "赵冬雨" 7 results
  • Clinical Study of Laparoscope Combined with Choledochoscope in Treatment of Patients with Cholecystolithiasis and Choledocholithiasis

    Objective To study the clinical effects of laparoscope combined with choledochoscope in patients with cholecystolithiasis and choledocholithiasis. Methods Clinical data of 74 patients with cholecystolithiasis and choledocholithiasis between Mar. 2009 and Feb. 2011 in our hospital were retrospectively analyzed. Among them, 37 cases underwent the laparoscope combined with choledochoscope operation (referred to as the double mirror operation group) and 37 cases underwent the conventional open operation (open operation group). The intraoperative conditions, therapeutic effect, and complications of patients in 2 groups were compared. Results The stone clearance rates of the two groups were 100%. The recurrence rate of 2 groups in the follow-up process was no significantly difference (P>0.05). In the double mirror operation group, the operative time was significantly longer than that open operation group (P<0.01);the intraoperative bleeding was significantly less than that open operation group (P<0.01);the anal exhaust time after operation, get out of bed time after operation, and total duration of hospitalization were significantly shorter than that open operation group (P<0.01);and the incidence of postoperative complications was significantly lower than that open oper-ation group(P<0.01). Conclusion Laparoscope combined with choledochoscope in treatment of cholecystolithiasis and choledocholithiasis patients has exact effects, with minor trauma, quicker recovery, and fewer complications, and it’s worthy of promotion.

    Release date:2016-09-08 10:35 Export PDF Favorites Scan
  • Short-Term Clinical Effect of Composite Digestive Enzyme Capsule in Treatment of Digestive Hypofunction after Cholecystectomy

    目的 探讨复合消化酶胶囊治疗胆囊切除术后消化功能减退症的临床疗效。方法 将84例胆囊切除术后出现消化功能减退的患者按住院日单双号原则分为对照组(n=41),给予抑酸药奥美拉唑肠溶胶囊与促胃肠道动力药多潘立酮片;观察组(n=43)加用复合消化酶胶囊。比较2组患者的临床疗效。结果 观察组显效14例,有效21例,好转7例,无效1例,总有效率为97.7%(42/43);对照组显效10例,有效15例,好转10例,无效6例,总有效率为85.4%(35/41)。观察组的临床疗效较优(P<0.05)。用药过程中均未发生不良反应。结论 复合消化酶胶囊对胆囊切除术后因胆汁分泌障碍而引起的消化功能减退症具有确切疗效。

    Release date:2016-09-08 10:34 Export PDF Favorites Scan
  • Influence on Liver Function and Immune Function of Laparoscopic and Open Cholecystectomy

    目的探讨腹腔镜与开腹胆囊切除术对患者肝功能及免疫功能的影响。 方法根据手术方式将84例胆囊良性病变患者分为腹腔镜胆囊切除术组(LC组,50例)及开腹胆囊切除术组(OC组,34例),比较2组患者手术前后肝功能及免疫功能指标的变化。 结果2组患者肝功能在手术前后不同时间点的差异均无统计学意义(P>0.05);LC组患者术后免疫功能各指标与术前比较无明显变化(P>0.05),OC组CD3+、CD4+及CD4+/CD8+在术后1 d及3 d均较术前明显降低(P<0.05),术后7 d恢复至术前水平(P>0.05)。 结论LC术可引起患者术后肝功能短暂异常,但对免疫功能无明显影响,可作为胆囊切除的首选术式。

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  • Clinical Effect of Gastric Bypass Surgery in Treatment for Patients with Type 2 Diabetes and Its Related Effect Factors

    目的探讨胃转流术治疗2型糖尿病的疗效及分析影响疗效的相关因素。 方法回顾性分析2009年1月至2012年7月期间我院收治的33例行胃转流术治疗的2型糖尿病患者的临床资料及随访情况。 结果33例患者治愈率为54.55%(18/33),总有效率为90.91%(30/33),无效3例。分析治愈及未治愈患者术前的临床资料发现,与未治愈患者比较,治愈患者的年龄更小、病程更短、2 h BG更低、BMI更大及空腹C肽更高(P<0.05)。 结论从本组有限资料的初步结果看,胃转流术治疗2型糖尿病临床效果确切,而对于低龄、病程短、BMI及空腹C肽较高和2 h BG较低的2型糖尿病患者可获得更好的治疗效果。

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  • Clinical Features and Surgical Treatment Experience of Gastric Stump Cancer in 60 Cases

    目的总结残胃癌的临床特点、治疗及预后情况。 方法回顾性分析笔者所在医院科室2003年1月至2008年1月期间收治的60例残胃癌患者的临床资料。 结果60例残胃癌发生于远端胃大部分切除+BillrothⅡ式重建后48例(80.0%),发生于远端胃大部分切除+BillrothⅠ式重建后9例(15.0%),发生于近端胃大部分切除术后3例(5.0%)。42例患者行根治性切除,其术后1、3及5年生存率分别为90.5%、57.1%及13.3%;18例行姑息性手术治疗,其术后1、3及5年生存率分别为16.7%、0及0。根治组患者的中位生存时间为36.7个月,姑息组为7.2个月,根治组的生存情况较好(χ2=76.98,P<0.001)。 结论残胃癌不易早期诊断,对于高发人群需定期复查胃镜,积极的外科治疗可以提高患者的生存率及生活质量。

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  • Analysis of Association Between The Polymorphisms of DNA Repair Gene XRCC1 and Susceptibility to Colorectal Cancer

    目的探讨DNA损伤修复基因XRCC1 Arg194Trp位点多态性与结直肠癌易感性的关系。 方法选取120例结直肠癌患者与120例正常对照者进行对比研究。取外周血提取DNA,采用限制性片段长度多态性聚合酶链反应(PCR-RFLP)技术对XRCC1 Arg194Trp基因多态性进行检测分析,比较不同基因型与结直肠癌易感性的关系。 结果2组观察对象在年龄、性别、吸烟、饮酒、饮食特点等常见暴露因素方面的差异均无统计学意义(P>0.05),变异基因型Arg/Trp+Trp/Trp出现频率在2组观察对象中分别为30.00%和24.17%,差异无统计学意义(P>0.05)。 结论XRCC1 Arg194Trp位点多态性与结直肠癌的易感性并无显著相关性。

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  • nalysis on Clinical Effects of Different Operations for Treating Gallbladder and Bile Duct Stones

    目的探讨腹腔镜联合胆道镜治疗胆囊及胆总管结石的临床疗效。 方法回顾性分析2010年1月至2013年1月期间收治于笔者所在科室的96例胆囊及胆总管结石患者的临床资料,根据手术方式分为开腹组、腹腔镜联合胆道镜+T管引流术组和腹腔镜联合胆道镜+放置鼻胆管一期缝合组3组。对3组患者的手术时间、术中出血量、肛门排气时间、住院时间、残石率、复发率、并发症发生率、手术有效率及术后淀粉酶和肝功能指标水平进行对比分析。 结果微创手术组与开腹组比较,患者的出血量、肛门排气时间、住院时间、残石率、复发率及并发症发生率均减少、缩短或降低,同时手术的有效率提高(P<0.05);腹腔镜联合胆道镜+放置鼻胆管一期缝合组术后淀粉酶和肝功能指标的水平较其他2组明显降低(P<0.05)。 结论微创手术创伤小,残石率及复发率低,并发症少,患者术后恢复快,是一种安全有效的治疗方式,值得临床推广应用。

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