From January, 1983 through December, 1993, 20 different types of operations were carried out to treat a total of 54 cases from trauma or deformities around the occipitocervical region, in which 4 patients died. The causes of the deaths were analyzed, and the main factors responsible for the mortality were improper selection of the wires for internal fixation, inadequate decompression from operation, incorrect operative technique and errors in the selection of anesthesia.
In the early stage of acute necrotizing pancreatitis (ANP) of experimental monkeys, the concentration of tumor necrosis factor (TNF) in blood was significantly increased. Stilamin could significantly reduce the level of TNF, decrease the mortality, and prolong the survival time of monkeys. The authors draw the conclusion that TNF is an important inflammatory media in the early stage of ANP. Stilamin can significantly inhibit the inflammatory process and has good effect in the treatment of ANP in experimental monkeys.
目的:研究早期连续性静脉-静脉血液滤过和反复间断静脉一静脉血滤治疗重症急性胰腺炎的临床价值。 方法:45例SAP患者随机分为CVVH组(25例)和RIVVH组(20例)。比较2组患者的生命体征、生化指标、治疗前后的APACHE Ⅱ评分、死亡率、好转率。 结果:CVVH 组中3例死于MODS,死亡率为12％,RIVVH组死亡3例 (15％),其差异有统计学意义(Plt;0.05);CVVH 组好转率为80％ (20/25),与RIVVH组的80％(16/20)一致。在治疗的早期阶段,对于改善生命体征,降低APACHEⅡ评分CVVH效果更显注,但随着治疗时间的延长,这种差异逐渐变小,在后期两组间不再存在疗效差异,最终疗效上没有明显的差异,而RIVVH组,在治疗费用和人员成本上具有优势。结论:早期RIVVH 治疗SAP可以作为SAP重要的辅助治疗措施。
目的 探讨胃肠道间质瘤（GIST）的临床表现及诊治方法。方法 回顾性分析2003～2008年期间我院收治的35例GIST患者的临床表现和随访资料。结果 GIST发生部位：胃22例（62.8%），小肠8例（22.9%），结直肠2例（5.7%），腹膜后或肠系膜3例（8.6%）。免疫组织化学检测显示，CD117 （＋） 32例（91.4%），CD34 （＋） 18例（51.4%），SMA （＋） 4例（11.4%），S100 （＋） 2例（5.7%）。35例患者均接受了手术治疗，其中根治性手术30例，非根治性手术5例，联合脏器切除10例。随访中位时间34个月，随访率为100%（35/35）。全组患者1、3、5年累积生存率分别为95.4%、87.2%和77.9%。本组患者中有3例术后复发转移患者服用甲磺酸伊马替尼的患者至今仍带瘤生存。患者的5年累积生存率与肿瘤大小、有无肿瘤坏死、核分裂数、肿瘤细胞核异型性、肿瘤部位及手术方式有关（P＜0.05 ）。结论 GIST主要通过术后病理和免疫组织化学检测明确诊断，完整的局部手术切除是最有效的治疗手段，复发转移病例需要手术与药物治疗的结合。
Objective To observe the treatment efficacy and safety of glucosamine hydrochloride tablets on uremia patients with knee osteoarthritis (OA). Methods A total of 118 uremia patients with knee OA were selected and randomly divided into the glucosamine hydrochloride tablets treatment group (treatment group) and the coated aldehyde oxystarch capsules group (control group) with 59 cases in each group. The course was 8 weeks. The Lequesne Index was assessed for curative effect evaluation, and the change of blood indexes was observed to evaluate drug safety. Results The total effective rate of Lequesne Index in the treatment group was 72.9%, while that in the control group was 13.6%; the difference was statistically significant (χ2=42.303, P<0.001). There was no significant change in the two groups before and after treatment in terms of the patients’ dialysis adequacy, routine blood, blood electrolytes, liver and kidney function (P>0.05). Conclusion Glucosamine hydrochloride tablets is curative and safe in the treatment of uremia patients with OA.