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find Author "赵海涛" 3 results
  • 创伤患者大量输血后凝血指标变化情况分析

    目的了解创伤患者大量输血后凝血指标变化情况。 方法选择2012年1月-2014年6月输血量≥1 500 mL的65例创伤患者为观察组,选取同期输血量<1 500 mL的65例创伤输血患者为对照组。对两组患者输血前与输血后第1、3、7天凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)及血小板计数(PLT)等指标进行检测。 结果输血前,观察组与对照组的PT、APTT、TT、FIB及PLT比较,差异均无统计学意义(P>0.05);输血前、输血后第1、3、7天对照组各项指标间比较,差异均无统计学意义(P>0.05)。输血后第1天,观察组与输血前和对照组比较,PT、APTT、TT明显升高,FIB及PLT明显下降(P<0.05);输血后第3天,观察组与输血前、输血后第1天及对照组比较,PT、APTT、TT明显降低,FIB、PLT明显升高(P<0.05);输血后第7天,观察组与输血前及对照组PT、APTT、TT、FIB及PLT比较,差异无统计学意义(P>0.05),与输血后第1天、第3天比较,差异均有统计学意义(P<0.05)。 结论大量输血虽是救治创伤患者的重要手段,但同时可能会使患者凝血功能发生紊乱。因此需严密监测凝血功能指标的变化情况,以便及时补充血液成分,提高输血疗效。

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  • Clinicopathological Features, Postoperative Survival and Prognostic Influencing Factors of Male Patients with Hepatocellular Carcinoma

    Objective To investigate the clinicopathological features, postoperative survival and prognostic influencing factors of male patients with hepatocellular carcinoma (HCC). Methods The clinicopathological features and the follow-up data of 155 male HCC patients who received hepatectomy from Jan. 1995 to Dec. 2002 were retrospectively analyzed and the prognostic influencing factors were defined by uni- and multi-variate analysis. Results Compared with 24 female patients at the same period, males were about six-year older and both of their hepatitis B surface antigen (HBsAg) and liver cirrhosis positive rates were higher (P<0.05), but there were no significant differences of the other clinicopathological parameters between the male group and the female group. Multivariate analysis showed that Edmondson-Steiner grade and portal vein tumor thrombosis (PVTT) were two independent prognostic influencing factors of both the overall survival and the tumor-free postoperative survival of male patients with HCC, while satellite nodule and tumor size only influenced the overall survival. Conclusion The main clinicopathological features and the postoperative survival of male HCC patients were similar than those of female’s. Tumor differentiation and biological behaviors were major factors affecting postoperative survival of male patients with HCC.

    Release date:2016-08-28 04:08 Export PDF Favorites Scan
  • AN ANTERIOR NEUROVASCULAR INTERVAL APPROACH FOR FIXATION OF ULNA CORONOID PROCESS FRACTURE

    ObjectiveTo investigate the advantages and effectiveness of anterior neurovascular interval approach for fixation of ulna coronoid process fracture. MethodsBetween February 2011 and April 2015, 8 patients with ulna coronoid process fracture were treated with open reduction and internal fixation by anterior neurovascular interval approach. There were 5 males and 3 females, aged from 14 to 62 years (mean, 34 years). Fractures were caused by falling in 5 cases, traffic accident in 2 cases, and crashing in 1 case. The time between injury and operation was 1-6 days (mean, 3.5 days). According to Adams classification, there were 4 cases of type II, 1 case of type III, 2 cases of type IV, and 1 case of type V. In 1 patient with joint instability, lateral collateral ligament repair was given through another incision after fixation of coroniod fracture and the hinged external fixator, and plast splin was used to fix in the other patients; function exercise was done after removal of external fixtion. ResultsAll incisions healed by first intention, and no complications of neurovascular injury and deep infection occurred. All patients were followed up 6-48 months (mean, 22 months). The healing time of fracture was 8-15 weeks (mean, 12.6 weeks). Mild myositis ossificans occurred in 1 case. The flexionextension arc of the elbow was (125.00±7.07)° and the forearm rotation was (135.00±7.07)°, showing no significant difference when compared with those of normal side[(126.88±7.53)° and (139.38±8.21)°] (t=0.469, P=0.654; t=2.198, P=0.054). According to Morrey's scale, the results were excellent in 6 cases, good in 2 cases; the excellent and good rate was 100%. ConclusionAnterior neurovascular interval approach for reduction and internal fixation of ulna coroniod fractures has the advantages of simple operation, less trauma, and larger operative field. It can be used alone or combined with other surgical approaches.

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