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find Author "邓太兵" 2 results
  • Analysis of the frontier and hotspot of screening technology for early lung cancer based on bibliometrics

    ObjectiveTo reveal and demonstrate the hotspots and further research directions in screening technology for early lung cancer, and provide references for the future studies. MethodsResearches related to lung cancer screening from 2011 to 2021 in the Web of Science database were included. Biblioshiny, a bibliometrics program based on R language, was used to perform content analysis and visualization of the included literature information. ResultsResearches related to lung cancer screening were increasing year by year. Six major cooperation groups were formed between countries. The current research hotspots in the field of early lung cancer screening technology mainly focused on the multi-directional fusion of radiographic imaging, liquid biopsy and artificial intelligence. ConclusionLow-dose spiral CT screening is still the most important and mainstream method for the screening of early lung cancer at present. The combination and integration of artificial intelligence with various screening methods and the innovation of novel testing and diagnostic equipment are the current research hotspots and the future research trend in this field.

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  • 自膨式金属支架对恶性气道疾病的疗效及影响术后生存的因素分析

    目的 探讨自膨式金属支架(self-expandable metallic stent,SEMS)治疗恶性气道疾病的疗效及影响支架置入术后生存的因素。方法 2020年2月—2022年6月在广安市人民医院住院治疗的恶性气道疾病患者,根据CSCO指南对患者进行抗肿瘤治疗的基础上,行SEMS置入治疗,收集患者的临床资料。数据用SPSS 23.0进行分析。P<0.05具有统计学意义。结果 共纳入54例患者,其中恶性中央气道狭窄(malignant central airway obstruction,MCAO)40例和恶性气管食管瘘(malignant tracheoesophageal fistula,MTEF)14例;咳嗽和呼吸困难为主要的临床表现;最常见的原发疾病为食管鳞状细胞癌、其次为肺鳞状细胞癌;合并肺炎的患者占87%,痰培养中最常见的病原菌为革兰阴性杆菌,其次为真菌。共置入支架58枚,其中直筒支架42枚、Y型支架16枚;支架置入后,气道狭窄程度较支架置入前明显改善,气促分级明显低于支架置入前,第一秒用力呼气容积明显高于支架置入前(P<0.05);SEMS置入后症状改善率为94.4%;3个月后总生存率为70.4%。多因素分析显示C反应蛋白浓度[OR=1.011,95%CI(1.001~1.020),P=0.016]为SEMS置入3个月后恶性气道疾病死亡的独立危险因素,白蛋白水平[OR=0.883,95%CI(0.781~0.997),P=0.045]为保护性因素。结论 SEMS在恶性气道疾病姑息性治疗中起着重要作用;支架置入前感染的有效控制、营养状况的改善对术后生存有利。

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