west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "郑艾" 9 results
  • 非手术分期法对预测宫颈癌淋巴结转移的价值

    宫颈癌为女性常见妇科肿瘤之一,具有年轻化趋势。由于淋巴结转移与否与患者预后相关,探讨无创术前检查对宫颈癌淋巴结累及情况的有效性,以淋巴结转移信息来指导治疗显得尤为重要。现对彩色多普勒超声、CT、正电子发射断层扫描、磁共振间接淋巴结造影等非手术分期法应用于宫颈癌淋巴结转移的判定作一综述,以期为临床实践作出一定的指导。

    Release date: Export PDF Favorites Scan
  • Clinical Analysis of 13 Patients with Cervical Cancer Associated with Pregnancy

    目的:探讨妊娠相关性宫颈癌的早期诊断、治疗和预后。方法:结合文献回顾分析我院2000年至2007年收治的13例妊娠相关性宫颈癌的诊治经过和预后。结果:妊娠相关性宫颈癌分化程度低,癌灶体积大,早期盆腔淋巴结转移率高,产褥期宫颈癌预后差。结论:宫颈细胞学检查应列为首次产检常规项目;妊娠期宫颈原位癌在密切随诊前提下可暂不予处理,待分娩后6~8周活检确认病变性质后,再采取相应治疗措施;新辅助化疗同样可为晚期别的妊娠相关性宫颈癌争取手术时机。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • 乙醛脱氢酶1与肿瘤干细胞相关性研究

    【摘要】 乙醛脱氢酶(acetaldehyde dehydrogenase,ALDH)广泛存在于不同组织中,是一类具有高度氧化活性的胞浆酶类。随着肿瘤干细胞理论的提出,ALHD1被发现为多种肿瘤干细胞的表面标志,在肿瘤的诊断、治疗、判断预后等方面发挥一定作用。现就ALDH1在不同肿瘤的具体作用及在放化疗耐药方面的机制作一综述。

    Release date:2016-09-08 09:24 Export PDF Favorites Scan
  • 瞬时感受器电位C亚族蛋白6通道与肿瘤发生的研究进展

    细胞内游离钙离子(Ca2+)与肿瘤关系密切, 直接参与调控肿瘤的生长、侵袭、转移和分化。瞬时感受器电位(TRP)是细胞膜上的一种非选择性阳离子通道,且被认为是最可能的钙库操纵性钙通道和受体操纵性钙通道的分子基础。TRP通道C亚族蛋白(TRPC)在多种细胞中表达。近年研究多发现调控Ca2+进入细胞的TRPC6通道与多种癌症的发生和浸润转移有关。如果能阻遏此过程,可能对肿瘤的治疗提供一个新的思路。现对近年来TRPC6通道与肿瘤的关系的相关研究作一综述。

    Release date: Export PDF Favorites Scan
  • 干细胞治疗卵巢功能低下性不孕的研究进展和挑战

    不孕不育发病率在世界范围内逐年增加,其中女性不孕患者50%~60%,其可能与生活环境及生活方式的改变有关。由于妇科恶性肿瘤发生率有逐年增加及年轻化趋势,卵巢功能缺陷或卵巢结构缺如导致生殖细胞缺陷的患者可能终身不孕,但干细胞移植治疗为这类患者带来了新的希望。干细胞是具有自我更新及多向分化潜能的未分化细胞,存在于胚胎、胎儿或成年各阶段,这些特点使其成为细胞治疗及再生医学领域的研究热点。理论上,在适宜条件下,干细胞能分化为包括雌性生殖细胞在内的三胚层不同类型细胞,进而形成机体不同组织及器官。现今,多能干细胞诱导分化为雌性生殖细胞的实验研究取得了一定的成果,因此,干细胞转分化为雌性生殖细胞从而进行细胞移植治疗及卵巢组织再生可能作为未来治疗不孕不育的新方法。此综述旨在总结干细胞向雌性生殖细胞转分化的研究进展及其应用于生殖医学所面临的挑战。

    Release date:2016-11-23 05:46 Export PDF Favorites Scan
  • 宫颈卵巢原发性双癌和宫颈癌卵巢转移的临床分析

    女性生殖系统多部位原发恶性肿瘤(multiple primary malignant carcinomas,MPMC)是指在同一女性生殖系统器官中,同时或先后原发于同一器官不同部位、或 2 个甚至多个器官的恶性肿瘤,其中以卵巢内膜原发性双癌发病率最高,宫颈卵巢原发性双癌较为罕见。然而与转移性癌相比较,MPMC 通常期别较早,预后较好,目前尚无国际公认的标准治疗模式。因此在临床诊疗过程中,要注意鉴别多个肿瘤发生关系的原发性和转移性,做到及时诊断、及时治疗,尽量减少误诊、漏诊。该文就宫颈卵巢原发性双癌及宫颈癌卵巢转移方面的临床特点进行了综述。

    Release date:2017-07-21 03:43 Export PDF Favorites Scan
  • 子宫动脉化疗栓塞在子宫切口妊娠中的研究进展

    【摘要】 剖宫产术后子宫切口妊娠(cesarean scar pregnancy,CSP)是指孕卵或胚囊着床于剖宫产术后子宫切口瘢痕处的一种少见而危险的异位妊娠,是剖宫产的远期并发症之一。若诊治不当,有引起子宫破裂和无法控制阴道大出血的风险,危及患者生命。近年来,随着微创介入治疗技术的发展,子宫动脉栓塞术被广泛用于CSP的治疗,并且可联合甲氨蝶呤动脉灌注,迅速有效止血,保留患者子宫和生育功能,为以后清宫治疗提供了必要条件,安全有效。现就子宫动脉化疗栓塞在CSP中的研究进展阐述如下。

    Release date:2016-08-26 02:18 Export PDF Favorites Scan
  • 卵巢上皮性癌脑转移

    卵巢上皮性癌(EOC)是妇科三大恶性肿瘤之一,其死亡率高。卵巢上皮性癌脑转移的发生率较低,但是其预后差,近年EOC的脑转移发生率有增高趋势。脑转移可通过患者的症状、体征、头颅CT、MRI等方法较易诊断。目前缺乏对卵巢上皮性癌脑转移的标准治疗方案。其治疗方法可选择手术、全脑放射治疗(WBRT)、立体定位放射治疗(SRS)、化学疗法,综合多种治疗方法效果优于单一治疗方式。

    Release date: Export PDF Favorites Scan
  • The prospective clinical controlled study of high intensity focused ultrasound and uterine artery embolization in the treatment of cesarean scar pregnancy

    Objective To investigate the clinical effect of high intensity focused ultrasound (HIFU) and uterine artery embolization (UAE) in the treatment of cesarean scar pregnancy (CSP). Methods A total of 152 patients with CSP diagnosed by B-type ultrasonography were enrolled prospectively in this study from June 2014 to May 2016 in Chengdu Women and Children’s Central Hospital and Suining Central Hospital. Six patients from Chengdu Women and Children’s Central Hospital and 84 from Suining Central Hospital for Volunteered HIFU treatment were regarded as observation group. The other 62 patients from Chengdu Women and Children’s Central Hospital were selected to accept UAE treatment voluntarily were designated as control group. The clinical efficacy and therapeutic safety of the two groups were compared after the treatment. Results Eighty-two patients (91.1%) in the observation group and 32 (51.6%) in the control group had a bleeding volume equal to 100 mL or lower during complete curettage of uterine cavity (P<0.05). The hospitalization expenses of the above two groups were respectively (25 126.51±1 473.49) and (32 928.42 ±1 579.35) yuan (P<0.05). The hospitalization time was (11.03±1.52) and (10.65±1.87) days respectively, and the difference was not statistically significant (P>0.05). There was no significant difference in the normal rate of human chorionic gonadotropin recovery between the observation group and the control group at 14 days after treatment (P>0.05). Eighty-seven patients (96.7%) in the observation group and 51 (82.3%) in the control group had their menstrual recovery to normal level at 2 months after treatment, and the difference was statistically significant (P<0.05). The incidence of postoperative complications was 1.1% and 6.4% in the observation group and the control group, respectively, and the difference was not statistically significant (P>0.05). Conclusions HIFU in the treatment of CSP is safe and effective. Compared with UAE, HIFU requires less cost with fewer complications, which is worth promoting.

    Release date:2017-05-18 01:09 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content