【摘要】 目的 探讨选择性乳腺导管造影对溢液性乳腺肿瘤的鉴别诊断价值。 方法 回顾性分析2005年1月-2009年7月50例溢液性乳腺肿瘤资料，所有患者均行钼靶X线平片摄影、选择性乳腺导管造影检查及手术病理确诊。 结果 17例乳腺癌主要表现为分支导管内不规则的充盈缺损伴导管壁破坏，导管阻塞中断、断续征、潭湖状充盈等征象；33例乳腺导管内乳头状瘤主要表现为大导管内光整的充盈缺损，导管壁多无破坏，并伴有导管扩张以及扭曲。 结论 选择性乳腺导管造影对溢液性乳腺肿瘤诊断和鉴别诊断具有重要价值。【Abstract】 Objective To evaluate the value of selective mammary ductography in the diagnosis of breast tumours with nipple discharge. Methods The clinical data of 50 patients with breast tumours with nipple discharge diagnosed in our department form January 2005 to July 2009 were analyzed retrospectively. All patients were proved by molybdenum target mammography, selective mammary ductography and pathology. Results Seventeen patients with breast cancer’s galactographic features were mostly irregular intraductal defect with ductal wall breakage and ductal obstruction in the peripheral ducts; 33 patients with intraductal papilloma’s galactographic features were smooth intraductal filling defect with ductal wall integrity and ductal dilatation and torsion in the main ducts. Conclusions Selective mammary ductography is useful in diagnosis and differentiation of the breast tumours with nipple discharge.