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find Author "陈泉" 6 results
  • 恶性颈动脉体瘤肺转移一例并文献复习

    目的 探讨恶性颈动脉体瘤(malignant carotid body tumor,MCBT)的发病机制、临床表现、影像学特点及治疗。方法 回顾 1 例确诊 MCBT 的患者资料并结合相关文献进行复习,以“颈动脉体瘤”、“肺转移”以及“carotid body tumor”、“lung metastasis”和“pulmonary metastasis”为检索词检索中国知网、万方、Pubmed 等数据库,对相关文献进行分析。结果 患者女,20 岁,以“头晕、伴咳嗽”为首发症状,胸部 CT 示两肺多发粟粒结节,在外院诊断“肺结核”,抗结核治疗 10 d 因出现胃肠道反应停用。入院查体发现左侧下颌角无痛性肿块,结合颈动脉 CT 血管成像(CT angiography,CTA)和正电子发射计算机体层显像联合计算机体层摄影检查结果,考虑 MCBT。文献复习共纳入 36 篇文献,合计 42 例患者。患者临床表现不典型。颈动脉CTA 病变征象呈“破杯征”,典型“抱球征”消失。手术是主要治疗方法,放射治疗、化学治疗作为辅助手段,基因检测和分子靶向治疗是近年来的研究方向。结论 MCBT 临床上缺乏特征性表现,当 CT 表现为粟粒结节样肺转移瘤时,易误诊为肺结核。应对入院患者进行细致查体,可疑患者行颈动脉 CTA 等检查,诊断后尽早彻底切除肿瘤以改善患者预后。

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  • Curative Effect Observation on Treatment of Lower Limb Thrombophlebitis ofSuperficial Phlebitis with Trivex Cutting System

    目的 探讨Trivex旋切术治疗下肢血栓性浅表静脉炎的临床疗效。方法 回顾性分析67例下肢血栓性浅表静脉炎病例的临床资料。患者术前给予丹参治疗、下肢静脉造影等术前准备; 然后行大隐静脉主干内膜剥脱、用Trivex旋切系统剖吸曲张静脉和静脉丛内的血栓; 术后给予低分子肝素抗凝、早期下床活动等处理。结果 全部患者的手术均顺利,术中及术后无肺栓塞发生。术后2例切口Ⅱ期愈合, 65例切口Ⅰ期愈合。所有病例术后3d均出院,住院时间(5±1) d。15例术后患肢有瘀斑者随访2周均消失; 7例出现内踝部麻木感,随访6个月消失; 本组患者均获随访6个月,未见复发者。结论 下肢血栓性静脉炎早期行以Trivex旋切术为主的综合治疗,其临床疗效好、住院时间短、创伤小及美容效果好,并可有效防止病情反复、深静脉血栓及肺栓塞的发生,是治疗下肢血栓性静脉炎的有效手段。

    Release date:2016-09-08 10:35 Export PDF Favorites Scan
  • 低分子肝素钙对急性深静脉血栓大鼠血清IL-6和TNF-α水平的影响

    目的探讨低分子肝素钙(LMWH)对急性下肢深静脉血栓(DVT)大鼠血清白介素6(IL-6)和肿瘤坏死因子α(TNF-α)水平的影响。 方法将57只SD大鼠随机分为空白对照组20只和DVT组37只,DVT组予以结扎近心端股静脉,空白对照组大鼠不予结扎。再将DVT组大鼠随机分为实验对照组18只和LMWH组19只。空白对照组和实验对照组大鼠均给予2 mL生理盐水皮下注射,LMWH组大鼠给予2 mL LMWH皮下注射,每12小时注射1次,60 h后停止注射。分别于术前、术后36 h和术后72 h测量3组大鼠左下肢膝关节上6 mm处的左下肢周径及血清IL-6和TNF-α水平,并进行组间比较。 结果术前空白对照组、实验对照组及LMWH组的左下肢周径、血清IL-6水平和血清TNF-α水平比较差异均无统计学意义(P>0.050),但术后36 h和术后72 h 3组的左下肢周径、血清IL-6水平和血清TNF-α水平比较差异均有统计学意义(P<0.050),均是实验对照组>LMWH组>空白对照组。 结论急性下肢DVT SD大鼠行LMWH治疗后其血清IL-6和TNF-α水平均明显降低,提示LMWH对急性下肢DVT具有抗炎作用。

    Release date:2016-10-21 08:55 Export PDF Favorites Scan
  • Clinical efficacy of AngioJet mechanical thrombectomy for the treatment of acute lower extremity arterial embolism and thrombosis

    ObjectiveThis study was aimed to evaluate the clinical efficacy of mechanical thrombectomy using the AngioJet System for the treatment of lower extremity acute arterial embolism and thrombosis.MethodsThe clinical data of 20 patients with acute lower extremity arterial embolism and thrombosis admitted to the Department of Vascular Surgery in the People’s Hospital in Gansu Province where the author worked from September 2016 to March 2017, were retrospectively analyzed. All patients were treated with the AngioJet mechanical thrombectomy system. Clinical data of the patients were retrospectively collected. The clinical efficacy of AngioJet mechanical thrombectomy wasanalyzed.ResultsEighteen (90.0%) of the 20 patients successfully completed the mechanical thrombectomy by using the AngioJet System. The mean time for hospital stay and operation was (4.2±1.4) d and (1.3±0.4) h, respectively. The average doses of urokinase and heparin during operation were (35.80±12.30) ×104 U and (45.10±8.30) mg, respectively. Two patients received a complementary treatment of incision for removing the thrombus. Two patients received catheter-directed thrombolysis after the mechanical thrombectomy, 5 patients received bare-metal stent implantation after balloon expansion. Clinical success was in 16 cases. According to the Cooley standard, 10 patients were in excellent condition,6 in good condition, 2 in fair condition, and 2 in poor condition. There were 2 cases of distal arterial embolization,2 cases of antecardial discomfort of bradycardia, and 4 cases of bleeding at the puncture point, but no serious bleeding complications such as gastrointestinal and intracranial hemorrhage occurred. A total of 16 patients presented myoglobinuria during and after operation. All patients were followed up for 6–12 months. The results of ultrasound examination showed that the artery was patency in 15 cases. One patient died of myocardial infarction in 9 months after surgery,2 patients developed lower extremity ischemia symptoms again after surgery, and 2 patients had lower extremity ulcer caused by lower extremity ischemia symptoms. During the follow-up period, no lower limb necrosis, amputation, and death occurred in the remaining patients.ConclusionsThe AngioJet mechanical thrombectomy system is safe and effective. Combined with the use of catheter-directed thrombolysis and stent implantation, the AngioJet mechanical thrombectomy could lead to quick recovery of the perfusion of the lower extremity and improve the limb salvage rates, exhibiting excellent clinical value.

    Release date:2019-08-12 04:33 Export PDF Favorites Scan
  • Endovascular intervention for iliac vein compression syndrome with acute lower extremity deep vein thrombosis

    ObjectiveTo evaluate the efficacy and safety of intracavitary treatment for iliac vein compression syndrome(IVCS)with acute lower extremity deep venous thrombosis (DVT).MethodsThe clinical data of 57 patients with IVCS and lower extremity DVT, who undergoing with stent implantation, balloon expansion and Angiojet rheolytic thrombectomy from June 2015 to June 2018, were retrospectively analyzed. The effect of treatment was evaluated by the changes of thigh circumference difference between the affected side and the healthy side, and the thrombosis clearance rate in the operating. In addition, the incidence of post-thrombotic syndrome (PTS) and stent patency rate were analyzed after long-term follow-up based on the change of Villaita scale score and ultrasound examination of lower extremity veins.ResultsThe success rate of surgical technique was 100%, and there was no pulmonary embolism during operating and postoperative. Lower extremity deep vein thrombosis clearance levels Ⅲ 48 cases (84.2%), Ⅱ 9 cases (15.8%), the changes of thigh circumference difference between the affected side and the healthy side from preoperative (5.8±1.7) cm to (3.7±1.0) cm. One year follow-up after operation, the primary patency rate of stent was 86.0% and PTS occurred in 8 patients (14.0%).ConclusionStent implantation, balloon expansion and Angiojet rheolytic thrombectomy for IVCS with acute lower extremity DVT is a safe, effective with low incidence of complications and efficient thrombus clearance.

    Release date:2020-04-28 02:46 Export PDF Favorites Scan
  • Chinese expert consensus on the prevention and treatment of venous thromboembolism in the elderly

    The incidence of venous thromboembolism (VTE) is relatively high in the elderly population, and the disability, mortality, and medical expenses caused by VTE are also high. However, in a large number of randomized controlled and non-randomized controlled studies related to VTE, sufficient attention has not been paid to the elderly population with multiple underlying diseases. Therefore, the vast majority of research results recommended by VTE guidelines come from younger patients and healthy elderly people, at the same time, most relevant VTE prevention and treatment guidelines or consensus are formulated for hospitalized patients, and for non-hospital elderly populations such as home and elderly care institutions that truly need attention and risk of VTE, their recommended opinions are uncertain. In this context, the Peripheral Vascular Disease Management Branch of the Chinese Geriatrics Society has developed a consensus among Chinese experts on the prevention and treatment of VET in the elderly, based on evidence-based evidence such as domestic and foreign guidelines and relevant research.

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