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find Author "陈诚" 7 results
  • Clinical status of advanced pancreatic cancer treated with high intensity focused ultrasound

    ObjectiveTo explore the application value of high intensity focused ultrasound (HIFU) in the treatment of advanced pancreatic cancer.MethodThe domestic and foreign literatures about studies of HIFU treating advanced pancreatic cancer in recent years were retrieved and summarized.ResultsHIFU could prolong the survival time, control pain, and enhance the body’s immune function in patients with advanced pancreatic cancer. There were no obvious serious complications during the treatment process. The combined treatment with radiotherapy, chemotherapy, and traditional Chinese medicine could obviously prolong the survival time and improve the quality of life for the patients with advanced pancreatic cancer.ConclusionsHIFU is an important component in the comprehensive treatment of advanced pancreatic cancer. However, because there is no uniform standard for the dosage of HIFU treatment, the sample size of many related studies is small, so the research results have certain limitations, so more studies are needed to improve their understanding of advanced pancreatic cancer in order to better serve clinical workin future.

    Release date:2021-02-08 07:10 Export PDF Favorites Scan
  • Research progress of Maze procedure treating atrial fibrillation

    Atrial fibrillation is the most common arrhythmia and is known to be in connection with stroke, dementia, heart failure and increased risk of death. For drug-refractory atrial fibrillation, surgical or catheter ablation is recommended. Early attempts to design procedures to ablate atrial fibrillation and restore sinus rhythm culminated in the Cox-Maze Ⅲ procedure, which was the first truly successful procedure. However, Cox-Maze Ⅲ procedure is complex and technically demanding, so it has been extensively modified with new techniques to create new types of surgical ablation procedures: Cox-Maze Ⅳ procedure, minimally invasive Cox-Maze Ⅳ procedure, and the latest “hybrid approach”. This review mainly discusses these surgical treatment strategies and the latest research progress.

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  • Current situation of corporate governance in China’s medical insurance agencies: challenges and countermeasures

    The study investigates the current status of corporate governance structures in medical insurance agencies in typical cities and provinces in China, highlighting the challenges faced by corporate governance in these institutions. It advocates for the continued comprehensive promotion of the nationwide establishment of a unified corporate governance framework for medical insurance agencies. Furthermore, it recommends enhancing the legislative support system for corporate governance in medical insurance agencies to ensure the effective implementation of decision-making powers within these organizations. Additionally, the study proposes actively establishing social evaluation and supervision mechanisms for corporate governance to further enhance the corporate governance structure of medical insurance agencies in China.

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  • 二尖瓣成形术治疗二尖瓣反流89例临床分析

    目的 总结二尖瓣成形术治疗二尖瓣反流患者的临床经验,分析其疗效。 方法 回顾性分析2007 年1 月至 2011 年 7月中国医科大学附属第一医院采用二尖瓣成形术治疗89 例二尖瓣中重度反流患者的临床资料,其中男 51例,女 38 例;年龄21~64 (48.6±13.6)岁;病程1周~21 年。术前经食管超声心动图及术中探查发现二尖瓣中度反流(Ⅲ级) 40 例,重度反流 (Ⅳ级) 49 例。56例二尖瓣脱垂,脱垂病变累及A2区4例、A3区5例、P2区25例、P3区14例,累及多处8例;其中二尖瓣腱索断裂37例,腱索冗长脱垂19例;瓣环扩大42例。手术方式:前叶腱索转移4 例 , 前叶人工腱索 6 例 ,前叶裂缝合2例,交界部缝合 6 例 ,后叶矩形切除加 Sliding (滑行) 技术43 例,后叶折叠缝合成形14例,后叶人工腱索12例,缘对缘成形 10 例和心包补片修补瓣叶穿孔 1 例,其中2种以上修复方式9例。全部患者均使用成形环加固瓣环。手术中应用注水试验和食管超声心动图检查评价成形效果。 结果 无围术期死亡。术后心脏超声心动图提示:二尖瓣无反流 (0 级)15 例,微量反流 (Ⅰ级)41 例,轻度反流 (Ⅱ级) 23 例,轻至中度反流 (Ⅲ级)10 例。所有患者均无二尖瓣狭窄。术后随访77例(86.52%),随访时间3~58 (12.3±18.7) 个月。随访期间1例死于脑血管意外;1例行二尖瓣置换术。 结论 综合运用多种二尖瓣成形技术治疗二尖瓣中重度反流,可获得良好的临床疗效。

    Release date:2016-08-30 05:51 Export PDF Favorites Scan
  • Research Progress of Implantable Biosensors for Continuous Glucose Monitoring

    Continuous glucose monitoring plays an important role in severe diabetic patients. However, there is no available commercial implanted glucose biosensor for long-term clinic application. This paper firstly introduces the classification of biosensors for continuous glucose monitoring, and then discusses the failure mechanism for implanted biosensors. After that, it points out the routes and tips to improve the life time of the biosensor, and finally looks forward to the future development of implanted glucose biosensors.

    Release date:2016-10-24 01:24 Export PDF Favorites Scan
  • The effects of post mastectomy radiation therapy to breast reconstruction: a systematic review and meta-analysis

    ObjectiveTo evaluate the effect of post mastectomy radiation therapy (PMRT) on breast reconstruction after mastectomy in breast cancer patients, in order to provide evidence support for clinical treatment decision.MethodsFive databases searched in the current study include the Cochrane Library, PubMed, CNKI, VIP and WanFang database. A systematic search for control trials was performed in each database from the starting date of each database to March 1, 2021. After the two evaluators independently selected literatures, extracted data and conducted quality evaluation according to the inclusion and exclusion criteria, the meta analysis was carried out by Revman 5.3 software.ResultsA total of 9 cohort studies (3 447 cases) were included, including 699 cases in PMRT group and2 748 cases in non-radiotherapy group. The results of meta-analysis showed that: PMRT was associated with significant increase in capsular contracture. The incidence of capsular contracture increased from 4.34% in the non-radiotherapy group to 34.10% in patients receiving PMRT [OR=9.25, 95%CI (3.76, 22.78), P<0.000 01]. In addition, PMRT was associated with a significant increase in incidences of reconstructive failure [OR=2.55, 95%CI (1.74, 3.74), P<0.000 01] and revisional surgery [OR=2.24, 95%CI (1.58, 3.18), P<0.000 01]. Moreover it was associated with a significant reduction in patient satisfaction [OR=0.29, 95%CI (0.15, 0.57), P=0.000 30] and cosmetic outcome [OR=0.26, 95%CI (0.15, 0.43), P<0.000 01].ConclusionThis meta-analysis demonstrates that breast cancer patients who received PMRT after breast reconstruction, the rate of adverse events is increased and patients’ satisfaction and cosmetic outcome are decreased.

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  • A method for photoplethysmography signal quality assessment fusing multi-class features with multi-scale series information

    Photoplethysmography (PPG) is often affected by interference, which could lead to incorrect judgment of physiological information. Therefore, performing a quality assessment before extracting physiological information is crucial. This paper proposed a new PPG signal quality assessment by fusing multi-class features with multi-scale series information to address the problems of traditional machine learning methods with low accuracy and deep learning methods requiring a large number of samples for training. The multi-class features were extracted to reduce the dependence on the number of samples, and the multi-scale series information was extracted by a multi-scale convolutional neural network and bidirectional long short-term memory to improve the accuracy. The proposed method obtained the highest accuracy of 94.21%. It showed the best performance in all sensitivity, specificity, precision, and F1-score metrics, compared with 6 quality assessment methods on 14 700 samples from 7 experiments. This paper provides a new method for quality assessment in small samples of PPG signals and quality information mining, which is expected to be used for accurate extraction and monitoring of clinical and daily PPG physiological information.

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