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find Keyword "预防与控制" 23 results
  • 糖尿病视网膜病变的药物防治研究现状

    长期高血糖可产生多途径代谢异常。以往糖尿病视网膜病变的药物治疗的研究多集中于抑制和拮抗血管内皮生长因子表达增加、蛋白激酶C的活化、蛋白质非酶糖基化产物的堆积、多元醇代谢通路的异常、生长激素、血管紧张素转换酶系统的作用等方面。近年来,色素上皮衍生因子、抗氧化应激和抑制炎症反应的药物及药物作用的多环节影响被引起关注。尽管某些药物实验和临床研究已取得了令人鼓舞的结果,但要开发出真正有效的防治药物还任重道远。

    Release date:2016-09-02 05:51 Export PDF Favorites Scan
  • 一氧化氮和氧自由基对培养的视网膜 神经节细胞的损伤

    Release date:2016-09-02 06:03 Export PDF Favorites Scan
  • OBSERVATION OF EFFECT OF LASER PHOTOCOAGULATION BEFORE INTRAOCULAR SILICONE OIL REMOVAL ON GUARDING AGAINST RECURRENCE OF RETINAL DETACHMENT

    PURPOSE:To observe the effect of laser/photocoagulation on prevention of recurrence of retinal datachment following removal of intraocular silicone oil. METHODS:Laser photocoagulation was performed in a series of 24 cases (24 eyes)which had been formerly operated on with vitreoretinal surgery and intraocular silicone oil tamponade for retinal datachment,2 weeks to 3 months before intraocular silicone oil removal. Argon green or krypton red laser photocoagulation were done in whole or half cycle scattered laser burns behind the sclera! ridge. RESULT:Among the 24 eyes ,after the intraocular silicone oil had been removed, 22 (91.7%)eyes had their retinas retained in normal position. CONCLUSION :Laser photocoagulation before removal of intraocular silicone oil might be helpful in avoiding the recurrence of retinal detachment. (Chin J Ocul Fundus Dis,1997,13: 197-198)

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  • Distribution of Multidrug Resistant Organism in Neonates Admitted to Hospital through Various Ways and Prevention and Control of Nosocomial Infection

    ObjectiveTo explore the distribution of multidrug resistant organism in neonates admitted to the hospital through various ways, and analyze the risk factors in order to avoid cross infection of multidrug resistant organism in neonatology department. MethodsA total of 2 124 neonates were monitored from January 2012 to July 2013, among which 1 119 were admitted from outpatient department (outpatient group), 782 were transferred from other departments (other department group), and 223 were from other hospitals (other hospital group). We analyzed their hospital stays, weight, average length of stay, and drug-resistant strains, and their relationship with nosocomial infection. ResultsAmong the 105 drug-resistant strains, there were 57 from the outpatient group, 27 from the other department group, and 21 from the other hospital group. The positive rate in the patients transferred from other hospitals was the highest (9.42%). Neonates with the hospital stay of more than 14 days and weighing 1 500 g or less were the high-risk groups of drug-resistant strains in nosocomial infection. Drug-resistant strains of nosocomial infection detected in the patients admitted through different ways were basically identical. ConclusionWe should strengthen screening, isolation, prevention and control work in the outpatient neonate. At the same time, we can't ignore the prevention and control of the infection in neonates from other departments or hospitals, especially the prevention and control work in neonates with the hospital stay of more than 14 days and weighing 1 500 g or less to reduce the occurrence of multiple drug-resistant strains cross infection.

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  • 开展科学研究,提升国内感染控制核心价值

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  • Investigation of Hospital Infection with Bacteria Producing Extended-spectrum β-lactamases in the Department of Neonatology

    ObjectiveTo investigate the situation of hospital infection with bacteria producing extended-spectrum β-lactamases (ESBLs), find the source of infection and analyze its transmission route, and take effective prevention and control measures to reduce the incidence of nosocomial infection. MethodsA hospital neonatal ward had six cases of ESBL-producing bacteria infections on February 16 to 26, 2012. According to the processing procedure for hospital infection outbreak, we carried out epidemiological investigation on the patient with suspected hospital infection, including checking the medical records, asking the doctor in charge about the patients'clinical symptoms, collecting sputum samples of the patients and environmental microbiology examination, etc. ResultsFour cases of infection were community-acquired, and two were nosocomial infection. Infection onsets were concentrated (between February 16 and February 26, 2012). Patients had similar clinical symptoms, including fever, cough, cough sputum, and lung wet rales, which showed a lower respiratory infection. Six strains of ESBL-producing Escherichia coli were isolated from the infected children, and their susceptibility reports were not entirely consistent, indicating that they did not belong to the same species and were not homologous pathogens. Through bedside survey, we also isolated from the environmental samples 6 ESBL-producing bacteria, and these bacteria were acquired from the milk countertops, kettle, ventilator tube, two doctors'nasal cavity, and the cleaners'nasal cavity in corresponding wards of those infected children. ConclusionThe infection does not belong to an outbreak of nosocomial infection, and it is only an aggregation event of ESBL-producing Escherichia coli. The symptoms of infection were mainly because of lower immunity of children themselves, plus not so good aseptic technique and management in the department of neonatology. Therefore, strengthening hand hygiene management of medical staffs, and regular environmental sanitation and disinfection can reduce the incidence of neonatal hospital infection.

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  • Targeted Supervision and Analysis of Surgical Site Infection

    ObjectiveTo analyze the relevant factors for surgical site infection. MethodsA total of 677 cases of surgery in one hospital from July 1 to December 31 in 2012 were surveyed (not including implant and cardiac intervention surgeries), which were divided into different groups according to the preoperative incision contamination level, and the postoperative healing of incisions were observed closely. After the patients were discharged, we investigated the situation of incisions by phone or periodic review, and forms were filled in on schedule. ResultsBy follow-up evaluation of the 677 cases, the incisions in 12 cases were infected and the infection rate was 1.77%. Polluted and infected (14.28%, 30.76%) incisions caused more infection than the clean and clean-polluted incisions (0.00%, 0.59%). The patients who stayed in hospital for 4 or more than 4 days before surgeries (infection rate was 4.55%) took more risk of infection than the patients whose preoperative time in hospital were 2-3 days (infection rate was 0.60%) and 1 or shorter than 1 day (0.68%). Perioperative use of antibiotics for longer than 72 hours will increase the risk of incision infection than those within 48 hours (7.69%, 0.00%; P=0.002). ConclusionSurgical site infection is related to the incision type. Shortening the preoperative in-hospital time will reduce the risk of infection. Long time use of antibiotics in perioperative period cannot prevent the postoperative infection effectively, but may increase the risk of infection.

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  • 医护一体医院感染预防与控制模式在医院感染管理中的效果评价

    目的探讨医护一体医院感染预防与控制(院感防控)模式在医院感染(院感)管理中的效果,以提高科室感染管理质量的作用,不断促进科室感染管理工作的持续改进。 方法2013 年9 月开始实施医护一体院感防控,采用自身前后对照研究的方法对传统院感防控模式(2013 年9 月前)和医护一体院感防控模式(实施后第3、6 个月评价)进行效果比较,从手卫生、医疗废物、消毒隔离、多重耐药菌、职业暴露和传染病监测上报6 个方面内容进行指标评价。 结果医护一体院感防控模式的实施在院感的医疗废物处理正确率、消毒隔离知识掌握正确率、职业暴露知识掌握正确率、传染病监测正确率5 个方面均高于传统院感防控模式,差异有统计学意义(P < 0.05);在手卫生执行和多重耐药菌感染的正确率方面虽有波动,但仍显示医护一体院感防控模式优于传统模式,差异有统计学意义(P < 0.05);医护一体院感防控模式实施后,科室院感防控综合水平从全院第34 名上升至第3 名。 结论医护一体院感防控模式对科室的院感监控有促进作用,对提高院感管理质量有重要意义。

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  • Introduction of guidelines for the prevention and control of surgical site infections

    Surgical site infections are the common healthcare-associated infections. This article introduced the guidelines on the prevention and control of surgical site infection in using from background, making progress, and recommendations, to give directions for clinicians and infection prevention and control professionals choosing appropriately for decreasing surgical site infection risks.

    Release date:2018-03-26 03:32 Export PDF Favorites Scan
  • New technique and progress of prevention and control of healthcare-associated infection

    The article summarized the national and international history and current situation of healthcare-associated infection control, and analyzed the tendency of new technique and progress in healthcare-associated infection control according to the experience in research and practice.

    Release date:2018-03-26 03:32 Export PDF Favorites Scan
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