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  • 中介素在心血管系统的研究进展

    【摘要】 中介素(intermedin,IMD)又称肾上腺髓质素2,是降钙素基因相关肽超家族的一员。IMD能够无选择性作用于降钙素受体样受体/受体活化修饰蛋白复合物,通过受体复合物上G蛋白的变构,激活下游的效应酶及离子通道,再进一步发挥生物学效应。IMD的作用广泛,其对血管的作用主要包括血管生成作用、外周血管扩张作用、中枢升压作用及抗血管钙化作用;其对心脏的作用主要包括正性肌力作用、正性频率作用、抗心肌肥厚的作用等。

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • Survey of Occupational Exposures and Protective Condition in Operating Room for Interventional Therapy

    ObjectiveTo evaluate the occupational exposures and protective condition of medical staff in operating room for interventional therapy. MethodsFrom September to November in 2014, 46 medical staff in the operating room for interventional therapy were adopted to complete the occupational exposures and protection situation survey. After that, we analyzed and scored all the questionnaires. ResultsThe awareness of the medical staff about occupational exposures and occupational protection in the operating room was low; the awareness rates of doctors, nurses, and radiology technicians were 74.2%, 63.0% and 66.7%, respectively. The general condition of implement of occupational protection measures of the medical staff was bad, and the average rate of the doctors, nurses and radiology technicians was 51.3%, 43.9%, and 15.2%. ConclusionThe implement rates of occupational protection measures of the medical staff in Operating Room for interventional therapy differ much from the awareness rates. The rates in doctors and nurses are higher than that in radiology technicians. We should strengthen the education of radiation damage and protection measures in doctors, and enhance the training of iatrogenic injuries related knowledge in clinical radiology technicians to reduce occupational hazards.

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  • An Analysis of the Relationship between Pulse Pressure, Pulse Pressure Index and Hyperuricemia in Middle-aged and Aged Residents in Chengdu

    【摘要】 目的 分析成都地区中老年居民脉压(pulse pressure, PP)及脉压指数(pulse presure index,PPI)与高尿酸血症(hyperuricemia,HUA)的关系。 方法 利用2007年5月代谢综合征研究调查资料(共1 061人),依据PP[≤60 mm Hg(1 mm Hg=0.133 kPa)、gt;60 mm Hg]和PPI(≤0.450、gt;0.450)将人群分为正常组及增高组,分析两组人群尿酸水平及HUA患病率,采用单因素回归及logistic回归分析PP及PPI与HUA关系。 结果 ①PP/PPI增高组血浆尿酸水平明显高于PP/PPI正常组,差异有统计学意义(P=0.000)。②PP/PPI增高组HUA患病率明显高于PP/PPI正常组,差异有统计学意义(P=0.026、0.027)。③单因素回归和logistic回归分析皆提示PP及PPI与HUA呈正相关。 结论 成都地区PP及PPI与血浆尿酸水平关系密切,PP/PPI增高可能是HUA的危险因素。【Abstract】 Objective To evaluate the relationship between pulse pressure (PP), pulse pressure index (PPI) and hyperuricemia (HUA) among middle-aged and aged residents in Chengdu. Methods Based on the level of PP [≤60 mm Hg (1 mm Hg=0.133 kPa),gt;60 mm Hg] and PPI (≤0.450,gt;0.450), We divided the 1 061 middle-aged or aged people into normal PP/PPI group and augmented PP/PPI group. All patients came from the survey for metabolic syndrome study in May 2007. We analyzed the distribution of serum uric acid (UA) and HUA, and analyzed the relationship between PP, PPI and HUA by using single-factor and logistic regression analysis. Results The index of UA in the augmented PP/PPI groups was higher than that in the normal groups with a significant difference (P=0.000). The prevalence of HUA in the augmented PP/PPI groups was statistically higher than that in the normal groups (P=0.026, 0.027). Single-factor and logistic regression analysis showed that PP and PPI were both positively correlated to HUA. Conclusion The abnormalities of PP and PPI are closely related to metabolism disorder in Chengdu, and high level of PP or PPI is probably risk factors for HUA.

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
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