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find Author "魏蔚" 16 results
  • 纵隔巨大肿瘤手术的麻醉处理二例

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
  • Echocardiography in Evaluation of Right Ventricular Function

    Abstract: Right ventricular dysfunction or right heart failure is a complex clinical syndrome and often leads to a poor prognosis and high mortality. In order to detect right ventricular dysfunction at an early stage, provide a therapy guidance and evaluate treatment outcomes, right ventricular function evaluation has aroused more and more concern in clinical physicians. With the advantages of being non-invasive, accuracy and repetitiveness, echocardiography is used extensively in the assessment of heart function. In this review, we focus on how to use echocardiography to evaluate right ventricular function easily, efficiently, accurately and sensitively, and provide a good foundation for its further clinical application.

    Release date:2016-08-30 05:51 Export PDF Favorites Scan
  • 主动脉夹层患者于全身麻醉诱导时出现癫痫样发作一例

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  • Feasibility of Measuring Descending Aortic Blood Flow Using Transesophageal Ultra-sound Doppler Technique under Cardiopulmonary Bypass

    ObjectTo evaluate the feasibility of measuring the descending aortic blood flow using transesophageal ultrasound Doppler under cardiopulmonary bypass (CPB). MethodWe retrospectively analyzed the clinical data of 10 adult patients accepted elective cardiac surgery under CPB in March 2014 year. There were 4 males and 6 females with a mean age of 44.5±12.3 years ranging from 24.5-64.0 years. The descending aorta diameter and velocity time integral (VTI) of blood flow of middle esophageal and lower esophageal of these patients were detected by transesophageal echocardiography (TEE) under CPB. We took the formula of classic ultrasound texting the blood flow to calculate the descending aorta blood flow (DABF). At the same time, we recorded the data of CPB and index of hemodynamics. Compared with the flow of CPB pump, we analyzed the correlation between pump flow and the raliability of DABF texting value under CPB. ResultsTwo patients quit the trail for blurred imaging. The quality of blood flow spectrum images aquirded from the middle esophageal were inferior to those from the lower esophageal (P < 0.01) in the 10 patients. Among the patients 90% of DABF from the middle esophageal and 50% of DABF from the lower esophageal were more than pump flow. however, the texting value had an excellence correlation to PF (r=0.795, r=0.825). ConclusionThe classical TEE technique can not obtain accurate blood flow during CPB.

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  • The application of cerebral oxygen saturation monitoring in cardiac and thoracic surgery

    Regional cerebral oxygen saturation cerebral oxygen saturation(rScO2) monitoring by using near-infrared spectroscopy(NIRS) is a simple, sensitive, continuous and noninvasive method, which can detect the change in oxygen supply and demand. It has already draw attentions and applications during perioperative in recent years. The technique was firstly used in cardiac surgery, thereafter some studies found thoracic surgery which mostly used one-lung ventilation also was necessary to monitor rScO2. A series of studies confirmed there were correlations among perioperative adverse events and rScO2. In this paper, we reviewed the basic principle of rScO2, summarized the applications of rScO2 in cardiac and thoracic surgery, discussed the existing problems.

    Release date:2017-12-04 10:31 Export PDF Favorites Scan
  • Effects of low-dose epinephrine on cerebral oxygen saturation and awakening time during one-lung ventilation: A randomized controlled trial

    Objective To evaluate the effects of low-dose epinephrine on cerebral oxygen saturation (rScO2) and awakening time during one-lung ventilation (OLV) for thoracic surgery. Methods Thirty consecutive patients undergoing lobectomy from March to July 2016 in our hospital were randomly divided into an epinephrine group (n=15, 8 males and 7 females at an average age of 58.70±11.40 years) or a saline group (n=15, 7 males and 8 females at an average age of 57.00±11.40 years). They were continuously infused with 0.01 μg/(kg·min) epinephrine or saline after general induction. Hemodynamics was maintained ±20% of the baseline value. All patients were ventilated by a pressure control mode during OLV with tidal volume of 5-8 ml/kg and end-tidal carbon dioxide tension (EtCO2) of 35-45 mm Hg. Regional cerebral oxygen saturation (rScO2) was monitored using near-infrared spectroscopy (NIRS) continuously. Results Compared with the saline group, the epinephrine group had a high rScO2 during OLV, with a statisitical significance at OLV 40 min and 50 min (67.76%±4.64% vs. 64.08%±3.07%, P=0.016; 67.25%±4.34% vs. 64.20%±3.37%, P=0.040). In addition, the awakening time of patients in the epinephrine group was shorter than that of the saline group (P=0.004), and the awakening time was associated with the duration of low-dose rScO2 (r=0.374). Conclusion Continuous infusion of 0.01 μg/(kg·min) could improve the rScO2 during OLV and shorten awakening time in thoracic surgery.

    Release date:2018-03-05 03:32 Export PDF Favorites Scan
  • Progress in application of preoperative cardiopulmonary reserve assessment in patients with lung resection surgery

    Surgical operation is the first choice for most patients who suffer from early non-small cell lung cancer. The risk of ordinary thoracic surgery is between intermediate and high risk. Due to the high incidence of postoperative pulmonary complications after thoracic surgery, preoperative cardiopulmonary reserve assessment is extremely necessary and important. In recent years, lots of assessment tools are clinically used, including pulmonary function tests, arterial blood gas analysis, breath-holding test and 6-minute walk test. In addition, cardiopulmonary exercise test is used extensively. This article reviews the current status of preoperative cardiopulmonary reserve assessment in thoracic surgery to guide clinical decisions, reduce postoperative complications and improve outcomes.

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  • Tissue Doppler Strain Rate Imaging to Evaluate the Impact of Dopamine and Milrinone on Left Ventricular Function of Patients Undergoing Heart Valve Replacement

    Abstract: Objective To use tissue Doppler strain rate imaging to evaluate the impact of low dose dopamine and milrinone on systolic and diastolic function of the left ventricle of patients undergoing heart valve replacement. Methods  Forty patients undergoing selective heart valve replacement in West China Hospital of Sichuan University between March and May 2011 were included in this study. All the patients were randomized into 2 groups with 20 patients in each group: milrione group and dopamine group. After anesthesia induction and before cardiopulmonary bypass setup, left ventricular ejection fraction (LVEF) was measured by echocardiography. Tissue Doppler strain rate imaging was used to measure the left ventricular lateral wall and midventricular segment from the four-chamber view, which was compared with Doppler parameters. Results LVEF, ratio of early-diastolic to end-diastolic velocity (E/A) of transmitral flow, ratio of mitral  inflow velocity to early diastolic velocity in the annulus (E/Et) of both 2 groups were significantly different between before and after dopamine and milrinone administration (P<0. 05). In the milrinone group, 4 segments systolic peak velocity (Vs), 1 segment early diastolic peak velocity (Ve), 4 segments late diastolic peak velocity (Va), 3 segments Ve/Va ratio, 2 segments systolic peak strain rate (SRs), 2 segments late diastolic peak strain rate (SRa), and 3 segments early diastolic peak strain rate SRe/SRa ratio after dopamine and milrinone administration were significantly higher than those before dopamine  and milrinone administration (P<0. 05). In the dopamine group, 4 segments systolic peak velocity (Vs), 1 segment Ve, 4 segments Va, 1 segment Ve/Va ratio, 2 segments SRs, 1 segment SRe, 1 segment SRa, and 1 segment SRe/SRa ratio after dopamine and milrinone administration were significantly higher than those before dopamine and milrinone administration (P<0.05). To compare the milrione group and dopamine group after medication administration, 2 segments Vs, 4 segments Va, 1 segment SRe, 1 segment SRa, 2 segments Ve/Va ratio, and 2 segments SRe/SRa ratio of the milrione group were significantly higher than those of the dopamine group (P<0.05), and 1 segment Vs, two segments SRs of the milrione group were significantly lower than those of the dopamine group (P<0.05). Conclusion Both milrinone and dopamine can improve left ventricular systolic function of perioperative patients undergoing heart valve replacement assessed by tissue Doppler strain rate imaging, while milrinone can improve the diastolic function of the left ventricle on the long axis more significantly.

    Release date:2016-08-30 05:28 Export PDF Favorites Scan
  • Ultrasonic Pre-locating Internal Jugular Venous Cannulation in Infants: A Prospective Comparison with the Anatomic Landmarks Method

    ObjectiveTo evaluate the ultrasonic pre locating internal jugular venous cannulation in infants, comparison with the external landmark technique.MethodsSixty two infants scheduled for cardiac surgery were randomized prospectively into two groups. In the anatomic landmarks group( n =30), the patient’s internal jugular vein(IJV) were cannulated by using the traditional method of palpation of carotid pulsation and identification of other anatomic landmarks. In the ultrasonic pre locating group ( n =32), an two dimensional ultrasound scanner image made for locating the puncture site of vessels was used with an operative probe of HP SONOS 4500 system. The number of attempts, success rate, and incidence of complications were compared for two groups.ResultsThe success rate was 100% vs 80% in the ultrasonic pre locating group vs anatomic landmarks group, with a 3.1% vs 26 7% incidence of carotid artery punctures and the number of attempts 1.57±1.04 vs 2.55±1.76. All differences were statistically significant ( P lt;0.05,0.05,0.01). Conclusion Ultrasonographic pre-localization of the IJV is superior to the anatomic landmarks technique in terms of overall success , and decreases incidence of carotid artery puncture.

    Release date:2016-08-30 06:24 Export PDF Favorites Scan
  • 参附注射液对体外循环中炎性反应的影响

    摘 要 目的 观察参附注射液对体外循环(CPB)中肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)的影响。方法 将20例人工心脏瓣膜置换术患者随机分成参附组和对照组(每组10例)。参附组分别于麻醉诱导前、CPB前及主动脉开放10分钟内分别静脉滴注参附注射液20ml、40ml和40ml,于CPB前、主动脉阻断前、主动脉阻断30分钟,主动脉开放15分钟和60分钟时采用放射免疫法测定两组血心中TNF-α和IL-6的含量。结果 主动脉阻断前、主动脉阻断30分钟、主动脉开放后15分钟和60分钟,对照组TNF-α值均明显高于参附组(P<0.05),各时点IL-6组间比较差别无显著性意义(P>0.05)。结论 参附注射液可降低主动脉开放后血浆TNF-α的含量,具有对抗CPB所致的炎性反应的作用,而对CPB中IL-6作用不明显。

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
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