Cardiovascular disease is the leading cause of death in the world. The influence of diet on atherosclerotic cardiovascular disease (ASCVD) should not be underestimated. In 2022, the American College for Preventive Cardiology (ASPC) issued guidelines, which emphasized the importance of changing dietary patterns for the prevention of ASCVD and its risk factors, recommended the best diet for ASCVD prevention, and discussed dietary recommendations for ASCVD prevention in special populations. This paper interprets this guideline, aiming to provide help for clinical practice.
In June 2022, the American Lipid Society released "NLA scientific statement on statin intolerance: a new definition and key considerations for ASCVD risk reduction in the statin intolerant patient", which provides the latest definition, modifiable factors, and treatment strategies of statin intolerance. According to the guidelines, for statin intolerance, the statin medication regimen should be adjusted first (reducing the dose, switching to another statin, reducing the frequency of medication), and if the patient is still intolerant, non-statin drugs should be considered to reduce the risk of ASCVD in the patient. The interpretation of this guideline will help clinicians and researchers identify, manage and intervene in the statin intolerance syndrome.