OBJECTIVE: To compare the clinical results of repairing bone defect of limbs with tissue engineering technique and with autogeneic iliac bone graft. METHODS: From July 1999 to September 2001, 52 cases of bone fracture were randomly divided into two groups (group A and B). Open reduction and internal fixation were performed in all cases as routine operation technique. Autogeneic iliac bone was implanted in group A, while tissue engineered bone was implanted in group B. Routine postoperative treatment in orthopedic surgery was taken. The operation time, bleeding volume, wound healing and drainage volume were compared. The bone union was observed by the X-ray 1, 2, 3, and 5 months after operation. RESULTS: The sex, age and disease type had no obvious difference between groups A and B. all the wounds healed with first intention. The swelling degree of wound and drainage volume had no obvious difference. The operation time in group A was longer than that in group B (25 minutes on average) and bleeding volume in group A was larger than that in group B (150 ml on average). Bone union completed within 3 to 7 months in both groups. But there were 2 cases of delayed union in group A and 1 case in group B. CONCLUSION: Repair of bone defect with tissue engineered bone has as good clinical results as that with autogeneic iliac bone graft. In aspect of operation time and bleeding volume, tissue engineered bone graft is superior to autogeneic iliac bone.
Objective To explore the interventions for traumatic floating knee. Method We retrospectively analyzed the data of 32 patients with traumatic floating knee. The following-up time is 6 to 22 months with average time of 11 months. Result All the followed-up patients got bone union. One patient was with plate revealed, 2 patientss were infectious, 2 patients were with lock pin broken. According to Floating Knee Damage Limb Function Evaluation Scale produced by Karlstrom, 21 patients were excellent, 6 were good, 4 were fair and one was poor, and the excellent and good rate was 84.3%. Conclusion Operation for traumatic floating can recover the alignment and stability of lower limber, recover knee function and reduce complication.