目的:回顾性研究人工肱骨头置换治疗复杂肱骨近端骨折患者的肩关节的情况,以进一步提高疗效。方法:对我院2004年至2007年27例肱骨近端骨折患者采用肱骨头置换术治疗,术中修复关节囊和肩袖,术后随访5~38月,评价其肩关节功能。结果:采用半关节成形改良评分系统SSMH综合评分,优:5例,良:17例,可:5例,优良率:815%。肩关节活动:平均前屈上举:96°,外旋:36°,内旋至L2水平。X片示假体无松动断裂,位置良好。结论:对于复杂的肱骨近端骨折,人工肱骨头置换是有效治疗手段,能够最大限度恢复期肩关节活动功能。
To summarize the medium-term cl inical result of bio-derived bone transplantation in orthopedics with tissue engineering technique. Methods From December 2000 to June 2001, 10 cases of various types of bone defect were treated with tissue engineered bone, which was constructed in vitro by allogenous osteoblasts from periosteum (1 × 106/ mL) with bio-derived bone scaffold following 3 to 7 days co-culture. Six men and 4 women were involved in this study, aged from 14 to 70 years with a median of 42 years. Among them, there were 2 cases of bone cyst, 1 case of non-union of old fracture, 6 cases of fresh comminuted fracture with bone defect, and 1 case of chronic suppurative ostemyel itis. The total weight of tissue engineered bone was 3-15 g in all the cases, averaged 7.3 g in each case. Results The wound in all the case healed by first intention. For 7 year follow up, bone union was completed within 3.0 to 4.5 months in 9 cases, but loosening occurred and the graft was taken out 1 year after operation in 1 case. The X-ray films showed that 9 cases achieved union except one who received resection of the head of humerus. No obvious abnormities were observed, and the function of affected l imbs met daily l ife and work. Conclusion Bio-derived tissue engineered bone has good osteogenesis. No obvious rejection and other compl ications are observed in the cl inical appl ication.