Our team proposed and constructed an Expert-knowledge and Data-driven Comprehensive Evaluation Model of Chinese Patent Medicine (EDCEM-CPM) using the machine learning algorithm. This model could improve the system of the comprehensive evaluation of the Chinese patent medicine in technology and provide measurement tools for Chinese patent medicine according to its characteristics. The model evaluates the multi-dimensional value of Chinese patent medicine by data pre-treatment, clustering algorithms, and data training steps, such as automatic learning weighting. This evaluation model is already in practice. In this paper, we introduced the establishment of the model with the calculation process for reference.
Objective To summarize and analyze the characteristics, advantages and disadvantages of the current governance framework for public health emergencies in China. Methods The CNKI, VIP, WanFang Data, CBM and PubMed databases were electronically searched to collect studies on the management of major infectious disease outbreaks in China from inception to April 15, 2023. The basic information and governance elements included in the study were extracted and analyzed. Results A total of 30 studies were included, and the time of issuance was from 2020 to 2022. Most of the studies were on COVID-19, focusing on the governance framework of big data governance, holistic governance, and multi-agent collaborative governance. The governance elements were mainly concentrated in three aspects: governance subject, governance cycle and institutional guarantee. The governance entities were concentrated on multi-agent collaborative governance, with the governance cycle mainly focused on in process governance, and the basic guarantee is a multiple guarantee with information technology big data as the main body. Conclusion The governance body of China's major infectious disease epidemic management framework has transitioned from a single entity to a multi entity collaborative governance. While increasing prewarning governance, attention should also be paid to governance during the post recovery period. In terms of system, comprehensive guarantees such as epidemic public opinion control system guarantees, privacy security guarantees, and psychological counseling guarantees should be added.
Objective To analyze the current research status, characteristics and development trend of traditional medicine-related clinical trials registration, and to provide ideas and directions for further development of traditional medicine clinical trials. Methods The International Traditional Medicine Clinical Trial Registry (ITMCTR) database was searched by computer from inception to June 30, 2024, with unlimited trial registration status, to collect all the clinical trials on traditional medicine, and analyzed in terms of the basic information of the trials, the diseases studied and the interventions. Results A total of 4 349 clinical trials related to traditional medicine were included, with the number of registrations peaking in the second half of 2020, and showing a steady upward trend after 2023. The studies conducted covered a total of 47 countries/regions, led by Beijing, Shanghai, Guangdong, Sichuan, and Zhejiang provinces, accounting for 69.72% of the total, and included 13 overseas regions. The financial support for the studies was dominated by local government funds in various provinces and cities, accounting for 29.66%. Disease types studied were mainly circulatory system diseases, musculoskeletal system or connective tissue diseases, and tumor diseases, accounting for 29.91% of the total. 3 751 (86.3%) clinical trials were interventional studies, of which randomized parallel control was predominant, and there were 213 large-sample studies with a sample size of more than 1 000 cases. A total of 20 types of interventions were involved, of which 1 114 (29.86%) clinical trials utilized oral herbal soup/granule interventions. Conclusion Clinical trial enrollment in traditional medicine has increased overall, but with significant geographic unevenness. Oral herbal soup/granule interventional studies are the mainstream hotspots. It is recommended to strengthen international cooperation, enrich the types of interventions, refine the trial design, and raise the awareness of researchers about the registration of high-quality traditional medicine clinical trials.