Objective To explore the clinical value of early enteral nutrition in severe acute pancreatitis （SAP） by percutaneous endoscopic gastrostomy/jejunostomy （PEG/J）.Methods Treatment condition of nighty patients with SAP were retrospectively analysed.The 90 patients were collected peripheral venous blood respectively on 1， 12， and 18 d after admission to hospital.Forty-five of them were in PEG/J group， the others were in control group. Serum IL-6，TNF-α and endotoxin were detected by enzyme-linked immunosorbent assay （ELISA），CD4 /CD8 was determinated by indirect immunofluorescence staining method （FITC-labeled）.Results On 12 d and 18 d，the levels of serum IL-6， TNF-α， and endotoxin in PEG/J group were lower than those in control group （P＜0.01）.The CD4 /CD8 was significantly higher than that in control group （P＜0.01）.In control group， 2 cases complicated upper gastrointestinal haemorrhage，4 cases complicated pancreatic pseudocysts， and 2 cases complicated double infection， the temperature became normal after about 13.5 d.In PEG/J group， there were not upper gastrointestinal haemorrhage and double infection，but 2 cases also complicated pancreatic pseudocysts， the temperature became normal after about 10.5 d.Conclusion The clinical effectiveness of early enteral nutrition in SAP by PEG/J is satisfactory.
ObjectiveTo systematically review studies investigating the rate of falls among Chinese elderly. MethodsThe CNKI, VIP, CBM, WanFang Data, EMbase, The Cochrane Library and PubMed databases were electronically searched to identify cross-sectional studies on the rate of falls in Chinese elderly published from January 1st, 2000 to December 31st, 2021. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies. Meta-analysis was then performed using Stata 16.0 software. Results A total of 54 cross-sectional studies, involving 111 098 cases were included. The results of meta-analysis showed that the rate of falls among Chinese elderly was 19.3% (95%CI 16.9% to 21.6%). Subgroup analyses showed that the fall rates were 16.1% and 21.9% for males and females, respectively. The rates for 60-69, 70-79, and >80 years age groups were 16.3%, 21.7%, and 27.3%, respectively. The rates for the North, South, East, Southwest, and Central parts of China were 16.6%, 17.9%, 18.7%, 22.0%, and 25.8%, respectively. For the urban and rural elderly, the rates were 16.4% and 23.1%, respectively. The rates for those with or without spouses were 24.2% and 26.8%, respectively, while for the solitary and non-solitary elderly were 21.1% and 17.8%, respectively. The rates for elderly with or without exercise habits were 22.1% and 27.1%, respectively. ConclusionThe rate of falls is high among Chinese elderly, especially among females, older individuals, those in Southwest China, rural individuals, those without spouse, solitary individuals and those without exercise habits.