Objective To compare the oncologic results between laparoscopic and open approach for the treatment of rectal cancer. Methods Five hundred and twenty patients with rectal cancer from Jan. 2003 to Dec. 2008 were non-randomly divided into laparoscopic (LS) and open surgery (OS) group. Local recurrence, distant metastasis and survival rate were compared between two groups. Results One hundred and eighty-six cases received laparoscopic resection and 334 cases received open operation. There were no statistically significant differences (SSD) of demographic data between two groups (Pgt;0.05). Mean follow-up was 30.3 months. No SSD was observed in 3-year cumulative survival rate (83% in LS and 80% in OS, P=0.549), distant metastasis rate (12.5% in LS and 15.6% in OS, P=0.368), incidence of incision seeding (0.6% in LS and 0 in OS, P=0.189), or cumulative survival (P=0.142). The differences of local recurrences rate (4.8% in LS and 10.7% in OS, P=0.028), 3-year cumulative disease-free survival rate (81% in LS and 68% in OS, P=0.009), and cumulative disease-free survival (P=0.010) between two groups were statistical significant. The differences of cumulative survival, cumulative disease-free survival, local recurrences， and distant metastasis according to the TNM stageⅠ or Ⅱ between two groups were not statistical significant. The differences of cumulative disease-free survival and local recurrences according to the TNM stage Ⅲ reached statistical significance (P=0.045 and P=0.047, respectively). Conclusion Oncologic results of laparoscopic resection are similar to those of open resection for rectal carcinoma．
ObjectiveTo systematically review the diagnostic value of automatic breast volume scanner (ABVS) and handheld ultrasound (HHUS) for benign and malignant breast lesions.MethodsPubMed, EMbase, Web of Science, Biosis Preview, The Cochrane Library, WanFang Data, CNKI, VIP and SinoMed databases were electronically searched to collect studies on HHUS versus ABVS for benign and malignant breast lesions from inception to May 31st, 2019. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies, and then, meta-analysis was performed by using Meta-Disc software.ResultsA total of 24 studies were included. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio for HHUS were 0.83 (95%CI 0.82 to 0.85), 0.81 (95%CI 0.79 to 0.82), 19.71 (95%CI 14.93 to 26.01), 4.05 (95%CI 3.49 to 4.69), 0.22 (95%CI 0.18 to 0.26), and for ABVS were 0.90 (95%CI 0.89 to 0.92), 0.88 (95%CI 0.87 to 0.89), 76.86(95%CI 55.13 to 107.17), 7.40 (95%CI 6.07 to 9.04), 0.11 (95%CI 0.09 to 0.14), respectively. The areas under the summary receiver operating characteristic curves in the differentiation of benign and malignant breast lesions were 0.88 and 0.96 for ABVS and HHUS, respectively.ConclusionThe current evidence shows that ABVS has higher value than HHUS in the diagnosis of benign and malignant breast tumor. Due to limited quality and quantity of the included studies, more high quality studies are needed to verify above conclusion.