ObjectiveTo explore the clinical effect of the whole-course integrated care and traditional nursing in perioperative period of percutaneous needle biopsy. MethodsA total of 198 patients treated between May 2012 and March 2013 were randomly divided into the traditional care group (control group) and the whole-process integrated care group (experimental group). Then, we compared between the two groups in terms of pain and anxiety levels, qualified rate of specimen and incidence of postoperative complications. ResultsQualified rate of specimen in the experimental group (97.94%) was significantly higher than that in the control group (85.15%) (χ2=10.312, P=0.001). After surgery, the rates of pneumothorax and bleeding were 3.09% and 4.12% in the experimental group, and 11.88% and 14.85% in the control group; the pain score of the experimental group was 4.25±1.38, and 6.12±1.87 in the control group. One hour before and 8 hours after surgery, the anxiety scores were 11.16±3.29, 8.47±2.52 in the experimental group, respectively, and were 16.26±3.17, 12.12±3.26 in the control group, respectively. There were significant differences between the two groups in all the above indexes (P<0.05). ConclusionWhole-course integrated care can significantly reduce pain and anxiety levels and the incidence of postoperative complications and improve the success rate of percutaneous needle biopsy.